There are 8 ways to get from Prague to Siena by plane, train, bus, train (Trenitalia), night train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Václav Havel Airport Prague (PRG) to Florence Peretola Airport (FLR)plane PRG - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 45m€75–227Bus
cheapest- Take the bus from Praha, ÚAN Florenc to Florence Villa Constanza Bus Stationbus N538 / ...
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
16h 22m€46–132Train
- Take the train from Praha Hlavni Nadrazi to Muenchen Hbftrain Ec
- Take the train from München Hbf to Verona Porta Nuovatrain 89
- Take the train from Verona Porta Nuova to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
17h 4m€175–303Train, night train, bus
- Take the train from Praha Hlavni Nadrazi to Linz Hbftrain Ec
- Take the night train from Linz Hbf to Venezia Mestrenighttrain Nj
- Take the train from Venezia Mestre to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
18h 25mFly to Bologna Guglielmo Marconi Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Bologna Guglielmo Marconi Airport (BLQ)plane PRG - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
7h 32m€89–249Fly to Pisa International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Pisa International Airport (PSA)plane PRG - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
6h 43m€72–234Bus, train
- Take the bus from Praha, ÚAN Florenc to Padua Bus Stationbus
- Take the train from Padova to Florence Santa Maria Novellatrain
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
17h 23mDrive 1,020.7 km
- Drive from Prague to Sienacar 1,020.7 km
11h€159–230
Prague to Siena by bus
Questions & Answers
The cheapest way to get from Prague to Siena is to bus which costs €45 - €140 and takes 16h 22m.
The fastest way to get from Prague to Siena is to fly and train which takes 6h 43m and costs €70 - €240.
No, there is no direct bus from Prague to Siena. However, there are services departing from Praha, ÚAN Florenc and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 16h 22m.
No, there is no direct train from Prague to Siena. However, there are services departing from Praha Hlavni Nadrazi and arriving at Siena via München Hbf, Verona Porta Nuova and Firenze S.M.N.. The journey, including transfers, takes approximately 17h 4m.
The distance between Prague and Siena is 851 km. The road distance is 1020.7 km.
The best way to get from Prague to Siena without a car is to bus which takes 16h 22m and costs €45 - €140.
It takes approximately 6h 45m to get from Prague to Siena, including transfers.
Prague to Siena bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Siena train services, operated by ÖBB EuroCity, depart from Praha Hlavni Nadrazi station.
The best way to get from Prague to Siena is to bus which takes 16h 22m and costs €45 - €140. Alternatively, you can train, which costs €170 - €310 and takes 17h 4m.
What companies run services between Prague, Czechia and Siena, Italy?
You can take a bus from Praha, ÚAN Florenc to Siena via Florence Villa Constanza Bus Station in around 16h 22m. Alternatively, you can take a train from Praha Hlavni Nadrazi to Siena via Muenchen Hbf, München Hbf, Verona Porta Nuova, and Firenze S.M.N. in around 17h 4m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 50m
- When
- Monday to Thursday
- Estimated price
- €110–370
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- €100–330
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 42m
- When
- Every day
- Estimated price
- €85–200
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Sunday
- Estimated price
- €55–180
Flights from Václav Havel Airport Prague to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Monday and Friday
- Estimated price
- €45–200
- Website
- volotea.com
Flights from Václav Havel Airport Prague to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Friday
- Estimated price
- €45–180
- Website
- austrian.com
Flights from Václav Havel Airport Prague to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 15m
- When
- Friday and Sunday
- Estimated price
- €80–340
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Tuesday to Sunday
- Estimated price
- €100–330
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Muenchen Hbf
- Ave. Duration
- 5h 43m
- Frequency
- Every 4 hours
- Estimated price
- €75–100
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
Train from Praha Hlavni Nadrazi to Linz Hbf
- Ave. Duration
- 3h 45m
- Frequency
- 4 times a day
- Estimated price
- €19–45
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from München Hbf to Verona Porta Nuova
- Ave. Duration
- 5h 29m
- Frequency
- Every 4 hours
- Estimated price
- €65–120
- Website
- https://int.bahn.de/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Verona Porta Nuova to Firenze S.M.N.
- Ave. Duration
- 1h 32m
- Frequency
- Every 4 hours
- Estimated price
- €23–75
- Schedules at
- trenitalia.com
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- €30–60
- Schedules at
- trenitalia.com
- Phone
- +420 221 111 122
- info@cd.cz
- Website
- cd.cz
Train from Praha Hlavni Nadrazi to Linz Hbf
- Ave. Duration
- 5h 53m
- Frequency
- Once daily
- Estimated price
- €17–35
- Website
- https://www.cd.cz/en/default.htm
- 2nd Class
- €17–25
- 1st Class
- €27–35
- Business
- €29–32
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Linz Hbf to Venezia Mestre
- Ave. Duration
- 9h 13m
- Frequency
- Once daily
- Estimated price
- €50–264
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €259–264
- Couchette Carriage
- €140–160
- Seating Carriage
- €50–65
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Venezia Mestre to Firenze S.M.N.
- Ave. Duration
- 2h 11m
- Frequency
- Once a week
- Estimated price
- €26–60
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €14–35
- Website
- https://www.italotreno.it/en
Train from Padova to Florence Santa Maria Novella
- Ave. Duration
- 1h 45m
- Frequency
- Every 2 hours
- Estimated price
- €24–50
- Website
- https://www.italotreno.it/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Praha, ÚAN Florenc to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 50m
- Frequency
- Twice daily
- Estimated price
- €50–120
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–16
- Website
- https://www.flixbus.co.uk
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Praha, ÚAN Florenc to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 30m
- Frequency
- Once a week
- Estimated price
- €40–80
- Website
- https://regiojet.com/
Bus from Praha, ÚAN Florenc to Padua Bus Station
- Ave. Duration
- 13h
- Frequency
- Once a week
- Estimated price
- €60–80
- Website
- https://regiojet.com/
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- €6–16
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–13
- Website
- https://marinobus.it/en/
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Prague to Siena bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Prague to Siena train services, operated by ÖBB EuroCity, arrive at Muenchen Hbf station.
Yes, the driving distance between Prague to Siena is 1021 km. It takes approximately 11h to drive from Prague to Siena.
Book your Prague to Siena train tickets online with Omio.
Book your Prague to Siena bus tickets online with Omio and FlixBus.
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