There are 7 ways to get from Prague to Siena by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Václav Havel Airport Prague (PRG) to Florence Peretola Airport (FLR)plane PRG - FLR
- Take the train from Firenze S.M.N. to Sienatrain
6h 45m€85–236Bus
cheapest- Take the bus from Praha, ÚAN Florenc to Florence Villa Constanza Bus Stationbus N538 / ...
- Take the bus from Florence Villa Constanza Bus Station to Sienabus N528 / ...
16h 40m€70–129Train, bus
- Take the train from Praha Hlavni Nadrazi to Muenchen Hbftrain Ec
- Take the train from München Hbf to Bologna Centraletrain 89
- Take the train from Bologna Centrale to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
15h 58m€209–474Drive 1,020.8 km
- Drive from Prague to Sienacar 1,020.8 km
11h€158–229Fly to Pisa International Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Pisa International Airport (PSA)plane PRG - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
6h 43m€71–214Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Václav Havel Airport Prague (PRG) to Bologna Guglielmo Marconi Airport (BLQ)plane PRG - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
7h 24m€72–294Bus via Padova
- Take the bus from Praha, ÚAN Florenc to Padua Bus Stationbus
- Take the bus from Padova to Florencebus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
18h 40m€89–123
Prague to Siena by train and bus
Questions & Answers
The cheapest way to get from Prague to Siena is to bus which costs €70 - €130 and takes 16h 40m.
The fastest way to get from Prague to Siena is to fly and train which takes 6h 43m and costs €70 - €220.
No, there is no direct bus from Prague to Siena. However, there are services departing from Praha, ÚAN Florenc and arriving at Siena via Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 16h 40m.
The distance between Prague and Siena is 851 km. The road distance is 1020.8 km.
The best way to get from Prague to Siena without a car is to train and bus which takes 15h 58m and costs €200 - €480.
It takes approximately 6h 45m to get from Prague to Siena, including transfers.
Prague to Siena bus services, operated by FlixBus, depart from Praha, ÚAN Florenc station.
Prague to Siena bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Yes, the driving distance between Prague to Siena is 1021 km. It takes approximately 11h to drive from Prague to Siena.
Book your Prague to Siena bus tickets online with Omio and FlixBus.
What companies run services between Prague, Czechia and Siena, Italy?
You can take a bus from Praha, ÚAN Florenc to Siena via Florence Villa Constanza Bus Station in around 16h 40m.
- Website
- lufthansa.com
Flights from Václav Havel Airport Prague to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €130–600
Flights from Václav Havel Airport Prague to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- €80–800
Flights from Václav Havel Airport Prague to Pisa International Airport via Frankfurt
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- €140–700
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport via Munich
- Ave. Duration
- 3h 6m
- When
- Every day
- Estimated price
- €100–460
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- €80–650
- Website
- swiss.com
Flights from Václav Havel Airport Prague to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- €95–270
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport via Zurich
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €70–290
- Website
- ryanair.com
Flights from Václav Havel Airport Prague to Pisa International Airport
- Ave. Duration
- 1h 40m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €50–180
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €50–180
- Website
- volotea.com
Flights from Václav Havel Airport Prague to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Monday and Friday
- Estimated price
- €50–170
- Website
- airdolomiti.it
Flights from Václav Havel Airport Prague to Bologna Guglielmo Marconi Airport via Frankfurt
- Ave. Duration
- 3h 35m
- When
- Wednesday to Sunday
- Estimated price
- €120–650
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–20
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
- Phone
- +43 5 1717
- Website
- oebb.at
Train from Praha Hlavni Nadrazi to Muenchen Hbf
- Ave. Duration
- 5h 43m
- Frequency
- Every 4 hours
- Estimated price
- €95–160
- Website
- https://www.oebb.at/en/reiseplanung-services/im-zug/unsere-zuege/eurocity-intercity
- Website
- https://shop.oebbtickets.at/en/ticket
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from München Hbf to Bologna Centrale
- Ave. Duration
- 6h 44m
- Frequency
- 3 times a day
- Estimated price
- €100–240
- Website
- https://int.bahn.de/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €12–24
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Praha, ÚAN Florenc to Florence Villa Constanza Bus Station
- Ave. Duration
- 14h 50m
- Frequency
- Twice daily
- Estimated price
- €70–130
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €4–8
- Website
- https://www.flixbus.co.uk
- Phone
- +420 222 222 221
- info@regiojet.cz
- Website
- regiojet.com
Bus from Praha, ÚAN Florenc to Florence Villa Constanza Bus Station
- Ave. Duration
- 16h 30m
- Frequency
- Once a week
- Estimated price
- €65–100
- Website
- https://regiojet.com/
Bus from Praha, ÚAN Florenc to Padua Bus Station
- Ave. Duration
- 13h
- Frequency
- Once a week
- Estimated price
- €60–90
- Website
- https://regiojet.com/
- Phone
- +39 098 3520 315
- info@fsbusitaliafast.it
- Website
- simetbus.it
Bus from Padova to Florence
- Ave. Duration
- 2h 56m
- Frequency
- 3 times a week
- Estimated price
- €25–29
- Schedules at
- simetbus.it
Want to know more about travelling around Italy
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