Rome2Rio

How to get fromSantander to Sienaby plane, train, bus or car

Find Transport to Siena

See all options

There are 9 ways to get from Santander to Siena by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane plane SDR - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 23m
    €115–252

  2. Fly to Pisa International Airport, train

    cheapest
    1. Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane plane SDR - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    8h 36m
    €63–243

  3. Bus, train via Lyon

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the train from Bordeaux St Jean to Massy Tgvtrain train Tgv
    3. Take the train from Massy - Palaiseau to Lyon Part Dieutrain train Tgv
    4. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Sienatrain train Re
    22h 58m
    €259–597

  4. Bus

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    26h 10m
    €112–195

  5. Drive 1,539 km

    1. Drive from Santander to Sienacar car 1,539 km
    15h 32m
    €243–351

  6. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Santander Airport (SDR) to Bologna Guglielmo Marconi Airport (BLQ)plane plane SDR - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Sienatrain train
    5h 32m
    €85–298

  7. Bus, train

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the train from Bordeaux St Jean to Marne La Vallee Chessytrain train Tgv
    3. Take the train from Marne La Vallee Chessy to Torino Porta Susatrain train Tgv
    4. Take the train from Torino Porta Susa to Firenze S.M.N.train train Fr
    5. Take the train from Firenze S.M.N. to Sienatrain train Re
    23h 29m
    €269–637

  8. Bus via Barcelona

    1. Take the bus from Santander E.A. to Barcelona, Estació d'Autobusos Nordbus bus
    2. Take the bus from Barcelona - North Bus Station to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    28h 28m
    €133–250

  9. Bus, train #2

    1. Take the bus from Santander to Padovabus bus
    2. Take the train from Padova to Firenze S.M.N.train train Fr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    29h 39m
    €93–139

Santander to Siena by bus, foot, and train

Calendar7Weekly Services
Duration22h 58mAverage Duration
Ticket€259Cheapest Price
See schedules

Questions & Answers

What companies run services between Santander, Spain and Siena, Italy?

You can take a bus from Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 26h 10m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

More Questions & Answers

Where to next?

Trips from Santander

Trips to Siena

Popular routes