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How to get fromSantander to SienaBy plane, bus, train, or car

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There are 7 ways to get from Santander to Siena by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, bus

    best
    1. Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane plane SDR - FLR
    2. Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus bus
    6h 44m
    €94–261
  2. Fly to Pisa International Airport, train

    cheapest
    1. Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane plane SDR - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    7h 26m
    €86–305
  3. Bus, train via Antony

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the train from Bordeaux St Jean to Massy Tgvtrain train Tgv
    3. Take the train from Massy Tgv to Lyon Part Dieutrain train Tgv
    4. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Sienatrain train Re
    22h 54m
    €301–579
  4. Bus via Bordeaux

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    25h 56m
    €119–208
  5. Drive 1,539 km

    1. Drive from Santander to Sienacar car 1,539 km
    15h 32m
    €243–350
  6. Bus, train

    1. Take the bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastiánbus bus
    2. Take the train from Hendaye to Lourdestrain train Ter
    3. Take the train from Lourdes to Pisa Centraletrain train
    4. Take the train from Pisa Centrale to Empolitrain train Re
    5. Take the train from Empoli to Sienatrain train Re
    28h 10m
    €200–364
  7. Bus

    1. Take the bus from Santander to Padovabus bus
    2. Take the bus from Padova to Florencebus bus
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    31h 5m
    €90–106

Santander to Siena by bus, foot, and train

Calendar7Weekly Services
Duration22h 54mAverage Duration
Ticket€301Cheapest Price
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Questions & Answers

What companies run services between Santander, Spain and Siena, Italy?

You can take a bus from Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 25h 56m.

Airlines
Train operators
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