There are 7 ways to get from Santander to Siena by plane, train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, train
best- Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane SDR - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 23m€107–232Bus
cheapest- Take the bus from Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
25h 52m€83–234Drive 1,539 km
- Drive from Santander to Sienacar 1,539 km
15h 32m€241–348Fly to Bologna Guglielmo Marconi Airport, train
- Fly from Santander Airport (SDR) to Bologna Guglielmo Marconi Airport (BLQ)plane SDR - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
5h 28m€92–320Fly to Pisa International Airport, train
- Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane SDR - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
8h 35m€156–236Bus, train via Donostia / San Sebastián
- Take the bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastiánbus
- Take the bus from San Sebastian Central Bus Station to Verona Viale Girolamo Cardinalebus
- Take the train from Verona Porta Nuova to Florence Santa Maria Novellatrain
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
26h 59mBus, train
- Take the bus from Santander to Padovabus
- Take the train from Padova to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
29h 36m
Santander to Siena by bus
Questions & Answers
The cheapest way to get from Santander to Siena is to bus which costs €80 - €240 and takes 25h 52m.
The fastest way to get from Santander to Siena is to fly and train which takes 5h 28m and costs €90 - €320.
No, there is no direct bus from Santander to Siena. However, there are services departing from Santander and arriving at Siena via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 25h 52m.
The distance between Santander and Siena is 1307 km. The road distance is 1539 km.
The best way to get from Santander to Siena without a car is to bus which takes 25h 52m and costs €80 - €240.
It takes approximately 7h 23m to get from Santander to Siena, including transfers.
Santander to Siena bus services, operated by FlixBus, depart from Santander station.
Santander to Siena bus services, operated by FlixBus, arrive at Bordeaux station.
Yes, the driving distance between Santander to Siena is 1539 km. It takes approximately 15h 32m to drive from Santander to Siena.
Book your Santander to Siena bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Siena, Italy?
You can take a bus from Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 25h 52m.
- Website
- ryanair.com
Flights from Santander Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 2h 5m
- When
- Sunday
- Estimated price
- €65–230
Flights from Santander Airport to Pisa International Airport via Valencia
- Ave. Duration
- 11h 25m
- When
- Sunday
- Estimated price
- €70–290
Flights from Santander Airport to Pisa International Airport via London Stansted
- Ave. Duration
- 11h 45m
- When
- Monday
- Estimated price
- €80–300
Flights from Santander Airport to Pisa International Airport via Madrid
- Ave. Duration
- 6h 5m
- When
- Monday and Friday
- Estimated price
- €70–290
Flights from Santander Airport to Pisa International Airport via Palma Mallorca
- Ave. Duration
- 7h
- When
- Monday
- Estimated price
- €70–280
- Website
- vueling.com
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €90–220
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 8h
- When
- Monday to Saturday
- Estimated price
- €90–350
Flights from Santander Airport to Florence Peretola Airport via Paris Orly
- Ave. Duration
- 7h 50m
- When
- Tuesday
- Estimated price
- €90–220
Flights from Santander Airport to Bologna Guglielmo Marconi Airport via Madrid
- Ave. Duration
- 5h
- When
- Monday to Friday
- Estimated price
- €75–290
- Website
- iberia.com
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 4h 40m
- When
- Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €90–220
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 7h 6m
- When
- Monday to Saturday
- Estimated price
- €90–350
Flights from Santander Airport to Bologna Guglielmo Marconi Airport via Madrid
- Ave. Duration
- 5h
- When
- Monday to Friday
- Estimated price
- €75–290
- Website
- britishairways.com
Flights from Santander Airport to Florence Peretola Airport via Edinburgh
- Ave. Duration
- 7h 40m
- When
- Saturday
- Estimated price
- €120–700
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €10
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €8
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €27–55
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
Train from Verona Porta Nuova to Florence Santa Maria Novella
- Ave. Duration
- 1h 31m
- Frequency
- 4 times a day
- Estimated price
- €17–50
- Website
- https://www.italotreno.it/en
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- Once a week
- Estimated price
- €24–50
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Santander to Bordeaux
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- €22–65
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €55–150
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–16
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- €6–23
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–13
- Website
- https://marinobus.it/en/
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastián
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- €16–23
- Website
- https://www.alsa.com/en/
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from San Sebastian Central Bus Station to Verona Viale Girolamo Cardinale
- Ave. Duration
- 19h
- Frequency
- 3 times a week
- Estimated price
- €55–80
- Website
- https://union-ivkoni.com/en
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €60–75
- Schedules at
- tabitatour.ro
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