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How to get fromSantander to Sienaby plane, train, bus, or car

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There are 7 ways to get from Santander to Siena by plane, train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Florence Peretola Airport, train

    best
    1. Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane plane SDR - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 38m
    €81–292
  2. Fly to Pisa International Airport, train

    cheapest
    1. Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane plane SDR - PSA
    2. Take the train from Pisa Centrale to Empolitrain train
    3. Take the train from Empoli to Sienatrain train
    6h 45m
    €77–330
  3. Bus, train via Lagny-sur-Marne

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the train from Bordeaux St Jean to Marne La Vallee Chessytrain train Tgv
    3. Take the train from Marne La Vallee Chessy to Lyon Part Dieutrain train Tgv
    4. Take the train from Lyon Part Dieu to Milano Centraletrain train Fr
    5. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    6. Take the train from Firenze S.M.N. to Sienatrain train Re
    22h 16m
    €322–530
  4. Bus

    1. Take the bus from Santander to Bordeauxbus bus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus bus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 443 / ...
    25h 30m
    €167–248
  5. Drive  1,538.7 km

    1. Drive from Santander to Sienacar car 1,538.7 km
    15h 37m
    €277–400
  6. Bus, train

    1. Take the bus from Estación de autobuses de Santander to Padovabus bus
    2. Take the train from Padova to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    29h 30m
    €156–211
  7. Bus via Turin

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Bordeaux - Belcier Bus Stopbus bus
    3. Take the bus from Bordeaux - Belcier Bus Stop to Turin - Vittorio Emanuele Bus Stationbus bus
    4. Take the bus from Turin Stura Bus Station to Siena Central Train Stationbus bus
    31h 20m
    €127–228

Santander to Siena by bus, foot, and train

Calendar2Weekly Services
Duration22h 16mAverage Duration
Ticket€322Cheapest Price
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Comparing Your Travel Options

What companies run services between Santander, Spain and Siena, Italy?

You can take a bus from Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 25h 30m.

Airlines
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