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How to get fromSantander to Sienaby plane, train, bus, train (Renfe) or car

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There are 9 ways to get from Santander to Siena by plane, train, bus, train (Renfe), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Santander Airport to Florence Peretola Airport, train

    best
    1. Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)planeSDR - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain
    9h 38m
    €86–303
  2. Bus

    1. Take the bus from Santander to Bordeauxbus
    2. Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
    3. Take the bus from Florence Villa Constanza Bus Station to Sienabus443 / ...
    25h 45m
    €99–217
  3. Train

    1. Take the train from Santander to Madrid ChamartíntrainAlv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
    3. Take the train from Marseille St Charles to Roma Terminitrain
    4. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    5. Take the train from Firenze S.M.N. to SienatrainRe
    35h 3m
    €203–465
  4. Drive 1,538.7 km

    1. Drive from Santander to Sienacar1,538.7 km
    15h 25m
    €244–352
  5. Bus to Bilbao Airport, fly to Florence Peretola Airport, train

    1. Take the bus from Santander E.A. to Bilbao Intermodalbus
    2. Fly from Bilbao Airport (BIO) to Florence Peretola Airport (FLR)planeBIO - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain
    9h
    €87–274
  6. Fly Santander Airport to Pisa International Airport, train

    1. Fly from Santander Airport (SDR) to Pisa International Airport (PSA)planeSDR - PSA
    2. Take the train from Pisa Centrale to Empolitrain
    3. Take the train from Empoli to Sienatrain
    9h 15m
    €127–249
  7. Fly Santander Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Santander Airport (SDR) to Bologna Guglielmo Marconi Airport (BLQ)planeSDR - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train
    3. Take the train from Firenze S.M.N. to Sienatrain
    7h 42m
    €97–260
  8. Bus, train

    1. Take the bus from Santander to Padovabus
    2. Take the train from Padova to Firenze S.M.N.trainFr
    3. Take the bus from Firenze Autostazione to Siena-Via Tozzibus131
    29h 32m
  9. Bus via Geneva

    1. Take the bus from Santander E.A. to Bilbao Intermodalbus
    2. Take the bus from Bilbao Intermodal to Geneva - Bus Stationbus
    3. Take the bus from Geneve, Gare Routiere to La Speziabus
    4. Take the bus from La Spezia Chiosco Palme Viale Italia to Siena Central Train Stationbus
    31h 55m
    €119–233

Santander to Siena by bus

Calendar5Weekly Buses
Duration25h 45mAverage Duration
Ticket€99Cheapest Price
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Questions & Answers

What companies run services between Santander, Spain and Siena, Italy?

You can take a bus from Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 25h 45m. Alternatively, you can take a train from Santander to Siena via Madrid Chamartín, Madrid-Atocha Cercanías, Madrid-Puerta de Atocha-Almudena Grandes, Marseille St Charles, Roma Termini, and Firenze S.M.N. in around 35h 3m.

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