There are 7 ways to get from Santander to Siena by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Florence Peretola Airport, bus
best- Fly from Santander Airport (SDR) to Florence Peretola Airport (FLR)plane SDR - FLR
- Take the bus from Firenze Autostazione to Siena-V Le V.Veneto N.5bus
6h 44m€94–261Fly to Pisa International Airport, train
cheapest- Fly from Santander Airport (SDR) to Pisa International Airport (PSA)plane SDR - PSA
- Take the train from Pisa Centrale to Empolitrain
- Take the train from Empoli to Sienatrain
7h 26m€86–305Bus, train via Antony
- Take the bus from Santander to Bordeauxbus
- Take the train from Bordeaux St Jean to Massy Tgvtrain Tgv
- Take the train from Massy Tgv to Lyon Part Dieutrain Tgv
- Take the train from Lyon Part Dieu to Milano Centraletrain Fr
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
22h 54m€301–579Bus via Bordeaux
- Take the bus from Santander to Bordeauxbus
- Take the bus from Bordeaux to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Sienabus 443 / ...
25h 56m€119–208Drive 1,539 km
- Drive from Santander to Sienacar 1,539 km
15h 32m€243–350Bus, train
- Take the bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastiánbus
- Take the train from Hendaye to Lourdestrain Ter
- Take the train from Lourdes to Pisa Centraletrain
- Take the train from Pisa Centrale to Empolitrain Re
- Take the train from Empoli to Sienatrain Re
28h 10m€200–364Bus
- Take the bus from Santander to Padovabus
- Take the bus from Padova to Florencebus
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
31h 5m€90–106
Santander to Siena by bus, foot, and train
Questions & Answers
The cheapest way to get from Santander to Siena is to bus which costs €85 - €110 and takes 31h 5m.
The fastest way to get from Santander to Siena is to fly and bus which takes 6h 44m and costs €90 - €270.
No, there is no direct bus from Santander to Siena. However, there are services departing from Santander and arriving at Siena via Bordeaux and Florence Villa Constanza Bus Station. The journey, including transfers, takes approximately 25h 56m.
The distance between Santander and Siena is 1284 km. The road distance is 1539 km.
The best way to get from Santander to Siena without a car is to bus and train via Antony which takes 22h 54m and costs €300 - €600.
It takes approximately 6h 44m to get from Santander to Siena, including transfers.
Santander to Siena bus services, operated by FlixBus, depart from Santander station.
Santander to Siena bus services, operated by FlixBus, arrive at Bordeaux station.
Yes, the driving distance between Santander to Siena is 1539 km. It takes approximately 15h 32m to drive from Santander to Siena.
Book your Santander to Siena bus tickets online with Omio and FlixBus.
What companies run services between Santander, Spain and Siena, Italy?
You can take a bus from Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 25h 56m.
- Website
- vueling.com
Flights from Santander Airport to Florence Peretola Airport via Paris Orly
- Ave. Duration
- 4h 45m
- When
- Saturday
- Estimated price
- €85–260
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- €85–450
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 7h 35m
- When
- Every day
- Estimated price
- €85–260
- Website
- iberia.com
Flights from Santander Airport to Florence Peretola Airport via Paris Orly
- Ave. Duration
- 4h 45m
- When
- Saturday
- Estimated price
- €85–260
Flights from Santander Airport to Florence Peretola Airport via Madrid
- Ave. Duration
- 7h 21m
- When
- Every day
- Estimated price
- €85–450
Flights from Santander Airport to Florence Peretola Airport via Barcelona
- Ave. Duration
- 7h 35m
- When
- Every day
- Estimated price
- €85–260
- Website
- ryanair.com
Flights from Santander Airport to Pisa International Airport via London Stansted
- Ave. Duration
- 8h 31m
- When
- Monday, Thursday, and Friday
- Estimated price
- €80–300
Flights from Santander Airport to Pisa International Airport via Charleroi
- Ave. Duration
- 10h 20m
- When
- Tuesday to Thursday
- Estimated price
- €75–290
Flights from Santander Airport to Pisa International Airport via Madrid
- Ave. Duration
- 4h 50m
- When
- Monday and Friday
- Estimated price
- €65–280
- Website
- transavia.com
Flights from Santander Airport to Pisa International Airport via Paris Orly
- Ave. Duration
- 9h
- When
- Thursday
- Estimated price
- €95–490
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 6m
- Frequency
- Every 4 hours
- Estimated price
- €100–170
- Website
- https://www.sncf-connect.com/en-en
Train from Massy Tgv to Lyon Part Dieu
- Ave. Duration
- 2h 4m
- Frequency
- Every 4 hours
- Estimated price
- €90–140
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Bordeaux St Jean to Massy Tgv
- Ave. Duration
- 2h 59m
- Frequency
- Once daily
- Estimated price
- €85–190
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
Train from Hendaye to Lourdes
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- €30–65
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Milano Centrale
- Ave. Duration
- 4h 44m
- Frequency
- Twice daily
- Estimated price
- €55–90
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 33m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €5–10
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €7–13
- Website
- https://www.trenitalia.com/en.html
Train from Lourdes to Pisa Centrale
- Ave. Duration
- 17h 32m
- Frequency
- Once a week
- Estimated price
- €140–240
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €45–90
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 2h 3m
- Frequency
- Twice daily
- Estimated price
- €40–80
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-V Le V.Veneto N.5
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Santander to Bordeaux
- Ave. Duration
- 6h
- Frequency
- Once daily
- Estimated price
- €30–50
- Website
- https://www.flixbus.co.uk
Bus from Bordeaux to Florence Villa Constanza Bus Station
- Ave. Duration
- 17h 15m
- Frequency
- Once daily
- Estimated price
- €85–150
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Siena
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €4–8
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- Website
- alsa.com
Bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastián
- Ave. Duration
- 2h 50m
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- https://www.alsa.com/en/
- Phone
- +4-0263-21.55.00
- Website
- tabitatour.ro
Bus from Santander to Padova
- Ave. Duration
- 25h 27m
- Frequency
- Twice a week
- Estimated price
- €55–75
- Schedules at
- tabitatour.ro
- Phone
- +39 098 3520 315
- info@fsbusitaliafast.it
- Website
- simetbus.it
Bus from Padova to Florence
- Ave. Duration
- 2h 56m
- Frequency
- 3 times a week
- Estimated price
- €25–29
- Schedules at
- simetbus.it
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