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How to get fromInterlaken to Sienaby train, bus, car or plane

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There are 6 ways to get from Interlaken to Siena by train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus via Florence

    best
    1. Take the train from Spiez to Domodossolatrain train Ec / ...
    2. Take the train from Domodossola to Milano Centraletrain train
    3. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    4. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131
    8h 58m

  2. Bus

    cheapest
    1. Take the bus from Interlaken Sonnenhof to Zürich HB Schweizerhofbus bus Shuttler L1 online shuttle
    2. Take the bus from Zurich Ausstellungsstrasse to Siena Central Train Stationbus bus Itabus
    14h 32m
    €54–113

  3. Train, bus

    1. Take the train from Spiez to Domodossolatrain train Ec / ...
    2. Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus bus 3
    3. Take the bus from Milan Malpensa Airport 1 P13 to Siena Central Train Stationbus bus
    12h 15m
    €57–141

  4. Drive 621.9 km

    1. Drive from Interlaken to Sienacar car 621.9 km
    6h 45m
    €107–154

  5. Train, fly to Florence Peretola Airport

    1. Take the train from Interlaken West to Zürich Flughafentrain train
    2. Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane plane ZRH - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 3m
    €139–327

  6. Train, fly to Bologna Guglielmo Marconi Airport

    1. Take the train from Interlaken West to Zürich Flughafentrain train
    2. Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane plane ZRH - BLQ
    3. Take the train from Bologna Centrale to Florence Santa Maria Novellatrain train
    4. Take the train from Firenze S.M.N. to Sienatrain train
    8h 49m
    €152–359

Zurich Airport (ZRH) to Florence Peretola Airport (FLR) flights

Calendar30Weekly Planes
Duration2h 9mAverage Duration
Ticket€77Cheapest Price
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Questions & Answers

What companies run services between Interlaken, Switzerland and Siena, Italy?

You can take a bus from Interlaken Sonnenhof to Siena Central Train Station via Zürich HB Schweizerhof and Zurich Ausstellungsstrasse in around 14h 32m.

Airlines
Train operators
Bus operators

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