There are 7 ways to get from Interlaken to Siena by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Spiez to Domodossolatrain Ec / ...
- Take the train from Domodossola to Rho Fiera Milanotrain
- Take the train from Milano Rogoredo to Bologna centraletrain
- Take the train from Bologna Centrale to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
9h 4m€72–217Bus
cheapest- Take the bus from Interlaken Sonnenhof to Zürich HB Schweizerhofbus
- Take the bus from Zurich Bus Station to Milanbus
- Take the bus from Milano, Autostazione Lampugnano to Sienabus 500 / ...
12h 32m€65–98Drive 621.9 km
- Drive from Interlaken to Sienacar 621.9 km
6h 45m€110–159Train, fly to Florence Peretola Airport
- Take the train from Interlaken West to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 3m€161–369Train, bus
- Take the train from Spiez to Domodossolatrain Ec / ...
- Take the train from Domodossola to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
9h 6m€65–162Train, bus via Rho
- Take the train from Spiez to Domodossolatrain Ec / ...
- Take the train from Domodossola to Rho Fiera Milanotrain
- Take the train from Rho Fiera to Florence Santa Maria Novellatrain
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
9h 10m€84–143Train, fly to Bologna Guglielmo Marconi Airport
- Take the train from Interlaken West to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Sienatrain
8h 44m€150–427
Interlaken to Siena by train
Questions & Answers
The cheapest way to get from Interlaken to Siena is to bus which costs €65 - €100 and takes 12h 32m.
The fastest way to get from Interlaken to Siena is to drive which takes 6h 45m and costs €110 - €160.
No, there is no direct bus from Interlaken to Siena. However, there are services departing from Interlaken Sonnenhof and arriving at Siena via Zurich Bus Station and Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 12h 32m.
No, there is no direct train from Interlaken to Siena. However, there are services departing from Interlaken West and arriving at Siena via Spiez, Domodossola, Milano Rogoredo, Bologna Centrale and Firenze S.M.N.. The journey, including transfers, takes approximately 9h 4m.
The distance between Interlaken and Siena is 633 km. The road distance is 621.9 km.
The best way to get from Interlaken to Siena without a car is to train which takes 9h 4m and costs €70 - €220.
It takes approximately 9h 4m to get from Interlaken to Siena, including transfers.
Interlaken to Siena bus services, operated by Shuttler, depart from Interlaken Sonnenhof station.
Interlaken to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Spiez station.
The best way to get from Interlaken to Siena is to train which takes 9h 4m and costs €70 - €220. Alternatively, you can bus, which costs €65 - €100 and takes 12h 32m.
What companies run services between Interlaken, Switzerland and Siena, Italy?
You can take a train from Interlaken West to Siena via Spiez, Domodossola, Rho Fiera Milano, Milano Rogoredo, Bologna Centrale, and Firenze S.M.N. in around 9h 4m. Alternatively, you can take a bus from Interlaken Sonnenhof to Siena via Zürich HB Schweizerhof, Zurich Bus Station, and Milano, Autostazione Lampugnano in around 12h 32m.
- Website
- swiss.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €80–200
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €80–260
- Website
- lufthansa.com
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- €120–550
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Spiez to Domodossola
- Ave. Duration
- 1h 7m
- Frequency
- 3 times a day
- Estimated price
- €30–55
- Website
- https://www.sbb.ch/en
Train from Interlaken West to Zürich Flughafen
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- €65–120
- Website
- https://www.sbb.ch/en
- Phone
- +41 58 327 32 71
- Website
- bls.ch
Train from Spiez to Domodossola
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €18–25
- Website
- https://www.bls.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Domodossola to Rho Fiera Milano
- Ave. Duration
- 1h 24m
- Frequency
- Every 2 hours
- Estimated price
- €8–10
- Website
- https://www.trenord.it/en/
Train from Domodossola to Milano Centrale
- Ave. Duration
- 1h 42m
- Frequency
- Every 2 hours
- Estimated price
- €8–11
- Website
- https://www.trenord.it/en/
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Domodossola to Rho Fiera Milano
- Ave. Duration
- 2h 3m
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Rogoredo to Bologna centrale
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €40–55
- Website
- https://www.italotreno.it/en
- Smart Economy
- €40–55
- Smart Flex
- €40–55
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €28–40
- Website
- https://www.italotreno.it/en
- Smart Economy
- €28–40
- Smart Flex
- €29–40
Train from Rho Fiera to Florence Santa Maria Novella
- Ave. Duration
- 2h 19m
- Frequency
- 3 times a day
- Estimated price
- €50–65
- Website
- https://www.italotreno.it/en
- Smart Economy
- €50–65
- Smart Flex
- €50–65
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Rogoredo to Bologna centrale
- Ave. Duration
- 1h 44m
- Frequency
- 5 times a day
- Estimated price
- €30–65
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €13–25
- Schedules at
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €40–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €30–70
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +41 44 552 0807
- contact@shuttler.ch
- Website
- shuttler.ch
Bus from Interlaken Sonnenhof to Zürich HB Schweizerhof
- Ave. Duration
- 1h 52m
- Frequency
- 5 times a week
- Estimated price
- €24–29
- Website
- https://shuttler.ch/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Zurich Bus Station to Milan
- Ave. Duration
- 3h 35m
- Frequency
- Every 3 hours
- Estimated price
- €17–30
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Siena
- Ave. Duration
- 4h 55m
- Frequency
- Every 4 hours
- Estimated price
- €23–40
- Website
- https://www.flixbus.co.uk
- Phone
- +39 800 142 424
- numeroverdetpl@regione.toscana.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Website
- https://www.at-bus.it/en
- Schedules at
- https://www.at-bus.it/en/lines-and-timetables
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More Questions & Answers
Interlaken to Siena bus services, operated by Shuttler, arrive at Zürich HB Schweizerhof station.
Interlaken to Siena train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Domodossola station.
Yes, the driving distance between Interlaken to Siena is 622 km. It takes approximately 6h 45m to drive from Interlaken to Siena.
Book your Interlaken to Siena train tickets online with Omio.
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