There are 6 ways to get from Interlaken to Siena by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus via Florence
best- Take the train from Spiez to Domodossolatrain Ec / ...
- Take the train from Domodossola to Milano Centraletrain
- Take the train from Milano Centrale to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
8h 58mBus
cheapest- Take the bus from Interlaken Sonnenhof to Zürich HB Schweizerhofbus Shuttler L1 online shuttle
- Take the bus from Zurich Ausstellungsstrasse to Siena Central Train Stationbus Itabus
14h 32m€54–113Train, bus
- Take the train from Spiez to Domodossolatrain Ec / ...
- Take the bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1bus 3
- Take the bus from Milan Malpensa Airport 1 P13 to Siena Central Train Stationbus
12h 15m€57–141Drive 621.9 km
- Drive from Interlaken to Sienacar 621.9 km
6h 45m€107–154Train, fly to Florence Peretola Airport
- Take the train from Interlaken West to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Florence Peretola Airport (FLR)plane ZRH - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 3m€139–327Train, fly to Bologna Guglielmo Marconi Airport
- Take the train from Interlaken West to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Bologna Guglielmo Marconi Airport (BLQ)plane ZRH - BLQ
- Take the train from Bologna Centrale to Florence Santa Maria Novellatrain
- Take the train from Firenze S.M.N. to Sienatrain
8h 49m€152–359
Zurich Airport (ZRH) to Florence Peretola Airport (FLR) flights
Questions & Answers
The cheapest way to get from Interlaken to Siena is to train and bus which costs €55 - €150 and takes 12h 15m.
The fastest way to get from Interlaken to Siena is to drive which takes 6h 45m and costs €100 - €160.
No, there is no direct bus from Interlaken to Siena station. However, there are services departing from Interlaken Sonnenhof and arriving at Siena Central Train Station via Zurich Ausstellungsstrasse. The journey, including transfers, takes approximately 14h 32m.
The distance between Interlaken and Siena is 612 km. The road distance is 621.9 km.
The best way to get from Interlaken to Siena without a car is to train and bus via Florence which takes 8h 58m and costs .
It takes approximately 8h 58m to get from Interlaken to Siena, including transfers.
Interlaken to Siena bus services, operated by Shuttler, depart from Interlaken Sonnenhof station.
Interlaken to Siena bus services, operated by Shuttler, arrive at Zürich HB Schweizerhof station.
Yes, the driving distance between Interlaken to Siena is 622 km. It takes approximately 6h 45m to drive from Interlaken to Siena.
There are 2272+ hotels available in Siena.
What companies run services between Interlaken, Switzerland and Siena, Italy?
You can take a bus from Interlaken Sonnenhof to Siena Central Train Station via Zürich HB Schweizerhof and Zurich Ausstellungsstrasse in around 14h 32m.
- Website
- swiss.com
Flights from Zurich Airport to Florence Peretola Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- €75–210
Flights from Zurich Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- €80–420
- Website
- lufthansa.com
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €110–350
- Website
- airdolomiti.it
Flights from Zurich Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 3h 10m
- When
- Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- €110–350
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Spiez to Domodossola
- Ave. Duration
- 1h 7m
- Frequency
- 3 times a day
- Estimated price
- €35–65
- Website
- https://www.sbb.ch/en
Train from Interlaken West to Zürich Flughafen
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- €50–85
- Website
- https://www.sbb.ch/en
- Phone
- +41 58 327 32 71
- Website
- bls.ch
Train from Spiez to Domodossola
- Ave. Duration
- 1h 41m
- Frequency
- Hourly
- Estimated price
- €17–24
- Website
- https://www.bls.ch/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Domodossola to Milano Centrale
- Ave. Duration
- 1h 42m
- Frequency
- Every 2 hours
- Estimated price
- €8–11
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Firenze S.M.N.
- Ave. Duration
- 3h 42m
- Frequency
- Once daily
- Estimated price
- €20–65
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Florence Santa Maria Novella
- Ave. Duration
- 36 min
- Frequency
- Hourly
- Estimated price
- €13–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 055 849 0505
- servizioclienti@at-bus.it
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Website
- https://www.at-bus.it/en
- Phone
- +39 0322 844 862
- comazzi@comazzibus.com
- Website
- comazzibus.com
Bus from Domodossola - Stazione Ferroviaria to Aeroporto Malpensa - Terminal 1
- Ave. Duration
- 1h 20m
- Frequency
- Every 4 hours
- Estimated price
- €9
- Website
- https://www.comazzibus.com/eng/index.php
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Milan Malpensa Airport 1 P13 to Siena Central Train Station
- Ave. Duration
- 6h 50m
- Frequency
- 6 times a week
- Estimated price
- €27–55
- Website
- https://www.itabus.it/en/home
Bus from Zurich Ausstellungsstrasse to Siena Central Train Station
- Ave. Duration
- 11h 30m
- Frequency
- Once daily
- Estimated price
- €30–65
- Website
- https://www.itabus.it/en/home
- Phone
- +41 44 552 0807
- contact@shuttler.ch
- Website
- shuttler.ch
Bus from Interlaken Sonnenhof to Zürich HB Schweizerhof
- Ave. Duration
- 1h 52m
- Frequency
- 5 times a week
- Estimated price
- €24–28
- Website
- https://shuttler.ch/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Zurich Ausstellungsstrasse to Siena Central Train Station
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- €55–85
- Website
- https://www.flixbus.co.uk
- Website
- global.flixbus.com
Bus from Zurich Ausstellungsstrasse to Siena Central Train Station
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Schedules at
- global.flixbus.com
Want to know more about travelling around Italy
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