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How to get fromPhiladelphia to Des Moinesby plane, bus (Flixbus), train, bus, car or bus (Greyhound)

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There are 8 ways to get from Philadelphia to Des Moines by plane, bus (Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Philadelphia International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    4h 22m
    $208–955

  2. Bus via Baltimore (Greyhound)

    cheapest
    1. Take the bus from Philadelphia to Baltimore Downtown Bus Stationbus bus
    2. Take the bus from Baltimore Downtown Bus Station to Chicago Bus Stationbus bus
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    29h 19m
    $139–368

  3. Bus

    1. Take the bus from Philadelphia to Allentownbus bus
    2. Take the bus from Allentown to Chicago Bus Stationbus bus
    3. Take the bus from Chicago to Des Moinesbus bus
    28h 55m
    $184–366

  4. Train, bus

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the bus from Chicago to Des Moinesbus bus
    29h 11m
    $166–1,069

  5. Drive 1,073.9 mi

    1. Drive from Philadelphia to Des Moinescar car 1,073.9 mi
    17h 29m
    $196–284

  6. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)plane plane DCA - DSM
    6h 25m
    $340–2,261

  7. Train, bus via Galesburg

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Burlingtonbus bus
    5. Take the bus from Burlington to Des Moinesbus bus
    30h 29m
    $214–1,448

  8. Train, bus #2

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    2. Take the bus from Chicago to Des Moinesbus bus Chicago
    35h 4m
    $174–590

Philadelphia to Des Moines by bus

Calendar7Weekly Buses
Duration28h 55mAverage Duration
Ticket$184Cheapest Price
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Questions & Answers

What companies run services between Philadelphia, PA, USA and Des Moines, IA, USA?

American Airlines, Allegiant Air, and three other airlines fly from Philadelphia International Airport (PHL) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Philadelphia to Des Moines via Allentown and Chicago in around 28h 55m.

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