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How to get fromPhiladelphia to Des MoinesBy plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

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There are 8 ways to get from Philadelphia to Des Moines by plane, bus (Greyhound), train, bus, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Philadelphia International Airport

    best
    1. Fly from Philadelphia International Airport (PHL) to Des Moines (DSM)plane plane PHL - DSM
    4h 22m
    $220–1,124

  2. Bus via Chicago

    cheapest
    1. Take the bus from Philadelphia Bus Station to Chicago Bus Stationbus bus FlixBus N2642
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    27h 30m
    $171–311

  3. Bus (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    25h 40m
    $184–354

  4. Train, bus via Chicago

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Take the train from Rockville Amtrak to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Bloomington-Normaltrain train
    4. Take the bus from Bloomington-Normal to Des Moinesbus bus
    31h 25m
    $314–701

  5. Drive 1,073.9 mi

    1. Drive from Philadelphia to Des Moinescar car 1,073.9 mi
    17h 41m
    $196–284

  6. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Des Moines (DSM)plane plane DCA - DSM
    6h 25m
    $358–1,708

  7. Train, bus

    1. Take the train from 30th Street Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Des Moinesbus bus Greyhound US0157S
    31h 55m
    $309–656

  8. Train, bus #2

    1. Take the train from 30th Street Station to Chicago Union Stationtrain train Cardinal
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    34h 24m
    $337–732

Philadelphia to Des Moines by bus (Greyhound)

Calendar7Weekly Buses
Duration25h 40mAverage Duration
Ticket$184Cheapest Price
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Questions & Answers

What companies run services between Philadelphia, PA, USA and Des Moines, IA, USA?

American Airlines, Allegiant Air, and three other airlines fly from Philadelphia International Airport (PHL) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Philadelphia Bus Station to Des Moines via Indianapolis Union Station in around 25h 40m.

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