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There are 4 ways to get from Madison to Des Moines by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  10 h 45 min

  1. Take the bus from Madison, WI - Univ. of Wisconsin to Dubuque, IA 122
  2. Take the bus from Dubuque, IA to Des Moines, IA 1485

$53 - $103

3 alternative options

Drive  •  5 h

  1. Drive from Madison to Des Moines 292.5 miles

$28 - $45

Fly from Madison  •  6 h 37 min

  1. Fly from Madison (MSN) to Des Moines (DSM) MSN - DSM

$166 - $856

Bus to Chicago O'Hare, fly  •  6 h 25 min

  1. Take the bus from Madison, WI-Langdon & N Park to Chicago, IL - O'Hare International Airport
  2. Fly from Chicago O'Hare (ORD) to Des Moines (DSM) ORD - DSM

$182 - $732

Questions & Answers

The cheapest way to get from Madison to Des Moines is to drive which costs $28 - $45 and takes 5 h.

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The quickest way to get from Madison to Des Moines is to drive which costs $28 - $45 and takes 5 h.

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No, there is no direct bus from Madison to Des Moines. However, there are services departing from Madison, WI - Univ. of Wisconsin and arriving at Des Moines, IA via Dubuque, IA. The journey, including transfers, takes approximately 10 h 45 min.

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The distance between Madison and Des Moines is 239 miles. The road distance is 292.5 miles.

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The best way to get from Madison to Des Moines without a car is to bus which takes 10 h 45 min and costs $50 - $110.

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It takes approximately 10 h 45 min to get from Madison to Des Moines, including transfers.

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Madison to Des Moines bus services, operated by Lamers Bus Lines, depart from Madison, WI - Univ. of Wisconsin station.

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The best way to get from Madison to Des Moines is to bus which takes 10 h 45 min and costs $50 - $110. Alternatively, you can fly, which costs $160 - $900 and takes 6 h 37 min.

Mode details

There is no direct flight from Madison Airport to Des Moines Airport. The quickest flight takes 3 h 13 min and has one stopover.

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Madison to Des Moines bus services, operated by Burlington Trailways, arrive at Des Moines, IA station.

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Map of how to get from Madison to Des Moines.
Launch map view
  • Distance: 239.1 miles
  • Duration: 10 h 45 min

What companies run services between Madison, WI, USA and Des Moines, IA, USA?

You can take a bus from Madison to Des Moines via Dubuque, IA and Dubuque, IA in around 10 h 45 min. Alternatively, United Airlines, American Airlines and Delta fly from Madison to Des Moines hourly.

Airlines
United Airlines
Website
united.com
Flights from Madison to Des Moines via Chicago O'Hare
Ave. Duration
3 h 53 min
When
Every day
Estimated price
$180 - $900
Flights from Madison to Des Moines via Denver
Ave. Duration
6 h 19 min
When
Every day
Estimated price
$250 - $1,100
Flights from Chicago O'Hare to Des Moines
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$290 - $1,400
American Airlines
Website
aa.com
Flights from Madison to Des Moines via Chicago O'Hare
Ave. Duration
3 h 44 min
When
Every day
Estimated price
$170 - $900
Flights from Madison to Des Moines via Dallas/Ft.Worth
Ave. Duration
5 h 37 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,100
Flights from Madison to Des Moines via Charlotte
Ave. Duration
6 h
When
Saturday
Estimated price
$260 - $1,100
Flights from Madison to Des Moines via Philadelphia
Ave. Duration
6 h 20 min
When
Every day
Estimated price
$270 - $1,100
Flights from Chicago O'Hare to Des Moines
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$330 - $1,100
Delta
Website
delta.com
Flights from Madison to Des Moines via Minneapolis
Ave. Duration
4 h 22 min
When
Every day
Estimated price
$160 - $850
Flights from Madison to Des Moines via Detroit
Ave. Duration
5 h 12 min
When
Every day
Estimated price
$190 - $950
Flights from Madison to Des Moines via Atlanta
Ave. Duration
5 h 14 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,100
Flights from Madison to Des Moines via New York La Guardia
Ave. Duration
7 h 26 min
When
Every day
Estimated price
$260 - $1,200
Bus operators
Lamers Bus Lines
Phone
+1 800-236-1240
Website
golamers.com
Bus from Madison, WI - Univ. of Wisconsin to Dubuque, IA
Ave. Duration
2 h 35 min
Frequency
Once daily
Estimated price
$22 - $28
Schedules at
golamers.com
Book at
webstore.golamers.com
Burlington Trailways
Vangalder Bus
Phone
+1 608-752-5407
Email
vangalder@coachusa.com
Bus from Madison, WI-Langdon & N Park to Chicago, IL - O'Hare International Airport
Ave. Duration
2 h 55 min
Frequency
Hourly
Estimated price
$30
Schedules at
vangalderbus.com
Book at
govangalder.com

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More Questions & Answers

Yes, the driving distance between Madison to Des Moines is 292 miles. It takes approximately 5 h to drive from Madison to Des Moines.

Get driving directions

American Airlines, United Airlines and Delta offer flights from Madison Airport to Des Moines Airport.

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There are 105+ hotels available in Des Moines. Prices start at $75 USD per night.

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