There are 6 ways to get from Madison to Des Moines by bus, night bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  9 h 55 min

  1. Take the bus from Madison, WI - Univ. of Wisconsin to Dubuque, IA 122
  2. Take the bus from Dubuque, IA to Des Moines, IA 1486

$73 - $98

Cheapest option

Bus, night bus  •  10 h 32 min

  1. Take the bus from Madison, WI University to Minneapolis, MN via Minneapolis
  2. Take the night bus from Minneapolis, MN to Des Moines, IA 805

$67 - $108

4 alternative options

Drive  •  5 h

  1. Drive from Madison to Des Moines 292.5 miles

$28 - $45

Fly Madison to Des Moines  •  6 h 19 min

  1. Fly from Madison (MSN) to Des Moines (DSM) MSN - DSM

$166 - $856

Bus to Chicago O'Hare, fly to Des Moines  •  6 h 23 min

  1. Take the bus from Madison, WI-Langdon & N Park to Chicago, IL - O'Hare International Airport
  2. Fly from Chicago O'Hare (ORD) to Des Moines (DSM) ORD - DSM

$182 - $732

Fly Madison to Waterloo, bus  •  10 h 54 min

  1. Fly from Madison (MSN) to Waterloo (ALO) MSN - ALO
  2. Take the bus from Waterloo, IA to Des Moines, IA

$263 - $1,187

Questions & Answers

The distance between Madison and Des Moines is 383 km. The road distance is 468 km.

The cheapest way to get from Madison to Des Moines is to drive which costs $28 - $45 and takes 5 h.

The quickest way to get from Madison to Des Moines is to drive which takes 5 h and costs $28 - $45.

No, there is no direct bus from Madison to Des Moines. However, there are services departing from Madison, WI - Univ. of Wisconsin and arriving at Des Moines, IA via Dubuque, IA. The journey, including transfers, takes approximately 9 h 55 min.

It takes approximately 9 h 55 min to get from Madison to Des Moines, including transfers.

What companies run services between Madison, WI, USA and Des Moines, IA, USA?

You can take a bus from Madison to Des Moines via Dubuque, IA in around 9 h 55 min. Alternatively, United Airlines, Delta and American Airlines fly from Madison to Des Moines hourly.

Airlines
American Airlines
Website
aa.com
Flights from Madison to Des Moines via Chicago O'Hare
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$170 - $900
Flights from Madison to Des Moines via Dallas/Ft.Worth
Ave. Duration
5 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,100
Flights from Madison to Des Moines via Philadelphia
Ave. Duration
6 h 24 min
When
Every day
Estimated price
$270 - $1,100
Flights from Chicago O'Hare to Des Moines
Ave. Duration
1 h 17 min
When
Every day
Estimated price
$330 - $1,100
Flights from Madison to Waterloo via Chicago O'Hare
Ave. Duration
3 h 30 min
When
Every day
Estimated price
$200 - $1,100
United Airlines
Website
united.com
Flights from Madison to Des Moines via Chicago O'Hare
Ave. Duration
4 h 20 min
When
Every day
Estimated price
$180 - $900
Flights from Madison to Des Moines via Denver
Ave. Duration
6 h 17 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,100
Flights from Chicago O'Hare to Des Moines
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$290 - $1,400
Delta
Website
delta.com
Flights from Madison to Des Moines via Minneapolis
Ave. Duration
3 h 31 min
When
Every day
Estimated price
$160 - $850
Flights from Madison to Des Moines via Detroit
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$190 - $950
Flights from Madison to Des Moines via Atlanta
Ave. Duration
5 h 18 min
When
Every day
Estimated price
$230 - $1,100
Bus operators
Lamers Bus Lines
Phone
+1 800-236-1240
Website
golamers.com
Bus from Madison, WI - Univ. of Wisconsin to Dubuque, IA
Ave. Duration
2 h 35 min
Frequency
Once daily
Estimated price
$22 - $28
Schedules at
golamers.com
Book at
webstore.golamers.com
Burlington Trailways
Website
burlingtontrailways.com
Bus from Dubuque, IA to Des Moines, IA
Ave. Duration
6 h 20 min
Frequency
Once daily
Estimated price
$50 - $70
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Waterloo, IA to Des Moines, IA
Ave. Duration
4 h 30 min
Frequency
Once daily
Estimated price
$40 - $60
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Megabus
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Night bus from Minneapolis, MN to Des Moines, IA
Ave. Duration
3 h 59 min
Frequency
Every 3 hours
Estimated price
$45 - $70
Schedules at
jeffersonlines.com
Vangalder Bus
Phone
+1 608-752-5407
Email
vangalder@coachusa.com
Bus from Madison, WI-Langdon & N Park to Chicago, IL - O'Hare International Airport
Ave. Duration
2 h 55 min
Frequency
Hourly
Estimated price
$30
Schedules at
vangalderbus.com
Book at
govangalder.com

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