There are 5 ways to get from Lexington to Des Moines by car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Covington, fly
best- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Des Moines (DSM)plane CVG - DSM
5h 30m$127–643Drive to Louisville International Airport, fly
cheapest- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Des Moines (DSM)plane SDF - DSM
5h 17m$101–482Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbusbus
- Take the bus from N Wilson Rd & Ferrell Pl - Columbus to Chicagobus
- Take the bus from Chicago Bus Station to Des Moinesbus
23h 34m$119–273Drive 650.4 mi
- Drive from Lexington to Des Moinescar 650.4 mi
11h 15m$119–172Fly from Blue Grass Airport
- Fly from Blue Grass Airport (LEX) to Des Moines (DSM)plane LEX - DSM
7h 39m$104–523
Covington (CVG) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Lexington to Des Moines is to drive which costs $110 - $180 and takes 11h 15m.
The fastest way to get from Lexington to Des Moines is to drive and fly which takes 5h 17m and costs $100 - $490.
The distance between Lexington and Des Moines is 595 miles. The road distance is 654.2 miles.
It takes approximately 5h 30m to get from Lexington to Des Moines, including transfers.
Des Moines is 1h behind Lexington. It is currently 2:52 PM in Lexington and 1:52 PM in Des Moines.
Yes, the driving distance between Lexington to Des Moines is 654 miles. It takes approximately 11h 15m to drive from Lexington to Des Moines.
There are 252+ hotels available in Des Moines.
What companies run services between Lexington, KY, USA and Des Moines, IA, USA?
United Airlines, Delta, and American Airlines fly from Blue Grass Airport (LEX) to Des Moines (DSM) every 2 hours.
- Website
- aa.com
Flights from Covington to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $95–600
Flights from Covington to Des Moines via Charlotte
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $150–750
Flights from Louisville International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $75–440
Flights from Louisville International Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 17m
- When
- Every day
- Estimated price
- $110–600
Flights from Blue Grass Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $140–700
Flights from Blue Grass Airport to Des Moines via Charlotte
- Ave. Duration
- 7h 33m
- When
- Every day
- Estimated price
- $120–650
Flights from Blue Grass Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 44m
- When
- Every day
- Estimated price
- $85–500
Flights from Blue Grass Airport to Des Moines via Philadelphia
- Ave. Duration
- 8h 13m
- When
- Every day
- Estimated price
- $150–750
- Website
- delta.com
Flights from Covington to Des Moines via Detroit
- Ave. Duration
- 6h 52m
- When
- Every day
- Estimated price
- $110–650
Flights from Covington to Des Moines via Minneapolis
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $120–650
Flights from Covington to Des Moines via Atlanta
- Ave. Duration
- 5h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–750
Flights from Louisville International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $90–490
Flights from Louisville International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $100–550
Flights from Louisville International Airport to Des Moines via Detroit
- Ave. Duration
- 7h 11m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $90–490
Flights from Blue Grass Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $120–600
Flights from Blue Grass Airport to Des Moines via Detroit
- Ave. Duration
- 7h 22m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–550
- Website
- united.com
Flights from Covington to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $95–600
Flights from Louisville International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $75–440
Flights from Blue Grass Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $85–500
- Website
- southwest.com
Flights from Covington to Des Moines via Chicago Midway
- Ave. Duration
- 4h 7m
- When
- Monday, Thursday, and Friday
- Estimated price
- $95–600
Flights from Louisville International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $70–440
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to N Wilson Rd & Ferrell Pl - Columbus
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $20–60
- Website
- https://baronsbus.com
Bus from N Wilson Rd & Ferrell Pl - Columbus to Chicago
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide






