There are 5 ways to get from Lexington to Des Moines by car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Covington, fly
best- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Des Moines (DSM)plane CVG - DSM
5h 10m$127–593Drive to Louisville International Airport, fly
cheapest- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Des Moines (DSM)plane SDF - DSM
5h 42m$106–482Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus
- Take the bus from Kansas City to Des Moinesbus
21h 29m$134–308Drive 650.4 mi
- Drive from Lexington to Des Moinescar 650.4 mi
11h 15m$119–172Fly from Blue Grass Airport
- Fly from Blue Grass Airport (LEX) to Des Moines (DSM)plane LEX - DSM
7h 37m$109–573
Covington (CVG) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Lexington to Des Moines is to drive which costs $110 - $180 and takes 11h 15m.
The fastest way to get from Lexington to Des Moines is to drive and fly which takes 5h 10m and costs $120 - $600.
The distance between Lexington and Des Moines is 595 miles. The road distance is 654.2 miles.
It takes approximately 5h 10m to get from Lexington to Des Moines, including transfers.
Des Moines is 1h behind Lexington. It is currently 9:29 AM in Lexington and 8:29 AM in Des Moines.
Yes, the driving distance between Lexington to Des Moines is 654 miles. It takes approximately 11h 15m to drive from Lexington to Des Moines.
There are 252+ hotels available in Des Moines.
What companies run services between Lexington, KY, USA and Des Moines, IA, USA?
United Airlines, Delta, and American Airlines fly from Blue Grass Airport (LEX) to Des Moines (DSM) every 2 hours.
- Website
- delta.com
Flights from Covington to Des Moines via Detroit
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $110–650
Flights from Covington to Des Moines via Minneapolis
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $120–650
Flights from Covington to Des Moines via Atlanta
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $140–750
Flights from Louisville International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $90–500
Flights from Louisville International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $110–550
Flights from Louisville International Airport to Des Moines via Detroit
- Ave. Duration
- 7h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–500
Flights from Blue Grass Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $120–650
Flights from Blue Grass Airport to Des Moines via Detroit
- Ave. Duration
- 7h 24m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Blue Grass Airport to Des Moines via Minneapolis
- Ave. Duration
- 7h 55m
- When
- Saturday
- Estimated price
- $110–600
- Website
- aa.com
Flights from Covington to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 49m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–600
Flights from Louisville International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 47m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–440
Flights from Blue Grass Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 47m
- When
- Every day
- Estimated price
- $150–750
Flights from Blue Grass Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $130–650
Flights from Blue Grass Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 29m
- When
- Every day
- Estimated price
- $90–550
- Website
- united.com
Flights from Covington to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $95–600
Flights from Louisville International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $75–440
Flights from Blue Grass Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Covington to Des Moines via Chicago Midway
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $95–550
Flights from Louisville International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 35m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $75–440
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Kansas City Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- Twice a week
- Estimated price
- $80–150
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
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