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How to get fromOhio to St. Louisby plane, bus (Flixbus, Greyhound), car, bus or bus (Greyhound)

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There are 8 ways to get from Ohio to St. Louis by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)planeCMH - STL
    3h 28m
    $292–620

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Columbus to St Louis Bus StationbusGreyhound US0421
    9h 5m
    $50–110

  3. Bus via Indianapolis

    1. Take the bus from Columbus to IndianapolisbusFlixBus N2640 / ...
    2. Take the bus from Indianapolis Union Station to St Louis Bus StationbusGreyhound US0421
    8h 39m
    $68–160

  4. Drive 416.3 mi

    1. Drive from Columbus to St. Louiscar416.3 mi
    6h 52m
    $76–110

  5. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)planeCLE - STL
    3h 50m
    $186–456

  6. Fly from Dayton

    1. Fly from Dayton (DAY) to Lambert–St. Louis International Airport (STL)planeDAY - STL
    6h 40m
    $165–1,005

  7. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)planeCVG - STL
    6h 14m
    $147–857

  8. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)planeDTW - STL
    5h 41m

Ohio to St. Louis by bus and foot

Calendar13Weekly Services
Duration8h 39mAverage Duration
Ticket$68Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and St. Louis, MO, USA?

Southwest Airlines and Delta fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) 4 times a day. Alternatively, you can take a bus from Columbus to St Louis Bus Station via Indianapolis and Indianapolis Union Station in around 8h 39m.

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