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How to get fromOhio to St. Louisby plane, bus (Greyhound), car or bus

Find Transport to St. Louis

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There are 7 ways to get from Ohio to St. Louis by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Cleveland-Hopkins International Airport

    best
    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    3h 50m
    $126–806

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    9h 5m
    $65–140

  3. Drive 416.3 mi

    1. Drive from Columbus to St. Louiscar car 416.3 mi
    7h
    $76–110

  4. Fly from John Glenn Columbus International Airport

    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    4h
    $405–606

  5. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 36m
    $147–857

  6. Fly from Dayton

    1. Fly from Dayton (DAY) to Lambert–St. Louis International Airport (STL)plane plane DAY - STL
    6h 26m
    $105–605

  7. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 37m
    $253–648

Ohio to St. Louis by bus (Greyhound)

Calendar21Weekly Buses
Duration9h 5mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and St. Louis, MO, USA?

Southwest Airlines, Delta, and two other airlines fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, Greyhound USA operates a bus from Columbus to St Louis Bus Station 3 times a day. Tickets cost $65–140 and the journey takes 9h 5m.

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