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How to get fromOhio to St. Louisby plane, bus (Flixbus, Greyhound), car, bus or bus (Greyhound)

Find Transport to St. Louis

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There are 8 ways to get from Ohio to St. Louis by plane, bus (Flixbus, Greyhound), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    4h
    $285–556

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    9h 5m
    $50–110

  3. Bus via Indianapolis

    1. Take the bus from Columbus to Indianapolisbus bus FlixBus N2640 / ...
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    8h 39m
    $63–115

  4. Drive 416.3 mi

    1. Drive from Columbus to St. Louiscar car 416.3 mi
    6h 56m
    $76–110

  5. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    4h 5m
    $176–416

  6. Fly from Dayton

    1. Fly from Dayton (DAY) to Lambert–St. Louis International Airport (STL)plane plane DAY - STL
    6h 53m
    $155–955

  7. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 27m
    $157–957

  8. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 41m

Ohio to St. Louis by bus and foot

Calendar13Weekly Services
Duration8h 39mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and St. Louis, MO, USA?

Southwest Airlines flies from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) 5 times a day. Alternatively, you can take a bus from Columbus to St Louis Bus Station via Indianapolis and Indianapolis Union Station in around 8h 39m.

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