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How to get fromOhio to St. Louisby plane, bus (Greyhound), car, or bus

Find Transport to St. Louis

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There are 7 ways to get from Ohio to St. Louis by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from John Glenn Columbus International Airport

    best
    1. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    3h 55m
    $105–656

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Columbus to St Louis Bus Stationbus bus Greyhound US0421
    9h 5m
    $65–140

  3. Drive 416.3 mi

    1. Drive from Columbus to St. Louiscar car 416.3 mi
    7h
    $76–110

  4. Fly from Cleveland-Hopkins International Airport

    1. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    3h 45m
    $126–706

  5. Fly from Covington

    1. Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane plane CVG - STL
    6h 6m
    $147–857

  6. Fly from Dayton

    1. Fly from Dayton (DAY) to Lambert–St. Louis International Airport (STL)plane plane DAY - STL
    6h 13m
    $125–755

  7. Bus to Detroit, fly

    1. Take the bus from Toledo to Dearbornbus bus
    2. Fly from Detroit (DTW) to Lambert–St. Louis International Airport (STL)plane plane DTW - STL
    5h 33m
    $273–648

Ohio to St. Louis by bus (Greyhound)

Calendar21Weekly Buses
Duration9h 5mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

What companies run services between Ohio, USA and St. Louis, MO, USA?

Southwest Airlines flies from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL) 4 times a day. Alternatively, Greyhound USA operates a bus from Columbus to St Louis Bus Station 3 times a day. Tickets cost $65–140 and the journey takes 9h 5m.

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