Directions from Cleveland to St. Louis

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3 h 42 min

  1. CLE - STL

$104 - $314

Cheapest option

Bus Greyhound USA  •  11 h 57 min

  1. 1537 / ...
  2. 1683 / ...

$60 - $155

3 alternative options

Train  •  13 h 16 min

  1. Capitol Limited / ...
  2. Lincoln Service / ...

$108 - $279

Bus Megabus  •  14 h 25 min

$61 - $86

Drive  •  9 h 22 min

  1. 560.4 miles

$55 - $80

What companies run services between Cleveland, OH, USA and St. Louis, MO, USA?

Southwest Airlines, Delta and two other airlines fly from Cleveland to St. Louis hourly. Alternatively, you can take a bus from Cleveland to St. Louis via Columbus, Oh in around 11 h 57 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Cleveland to St. Louis
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$210 - $550
Flights from Cleveland to St. Louis via Chicago Midway
Ave. Duration
3 h 22 min
When
Monday to Friday
Estimated price
$210 - $550
Delta
Website
delta.com
Flights from Cleveland to St. Louis via Detroit
Ave. Duration
3 h 42 min
When
Every day
Estimated price
$100 - $500
American Airlines
Website
aa.com
Flights from Cleveland to St. Louis via Chicago O'Hare
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$120 - $550
United Airlines
Website
united.com
Flights from Cleveland to St. Louis via Chicago O'Hare
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$100 - $650
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Cleveland Amtrak to Chicago Union Station Amtrak
Ave. Duration
6 h 46 min
Frequency
3 times a day
Estimated price
$55 - $150
Website
amtrak.com
Coach Seat
$55 - $85
Flexi Coach Seat
$100 - $150
Business Coach Seat
$100 - $150
Room
$260 - $360
Train from Chicago Union Station Amtrak to St. Louis Gateway Station Amtrak
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Cleveland, Oh to Columbus, Oh
Ave. Duration
2 h 25 min
Frequency
Hourly
Estimated price
$19 - $50
Website
greyhound.com
Economy
$19 - $30
Flexible
$35 - $50
Bus from Columbus, Oh to St Louis, Mo
Ave. Duration
9 h 10 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Cleveland, OH - Stephanie Tubbs Jones Transit Center Stop #3 to Chicago
Ave. Duration
7 h 40 min
Frequency
4 times a day
Estimated price
$30 - $50
Schedules at
us.megabus.com
Bus from Chicago to St. Louis
Ave. Duration
5 h 45 min
Frequency
4 times a day
Estimated price
$29 - $40
Schedules at
us.megabus.com

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Questions & Answers

The distance between Cleveland and St. Louis is 790 km. The road distance is 897 km.

The cheapest way to get from Cleveland to St. Louis is to drive which costs $55 - $80 and takes 9 h 22 min.

The quickest way to get from Cleveland to St. Louis is to fly which takes 3 h 42 min and costs $100 - $320.

No, there is no direct train from Cleveland to St. Louis. However, there are services departing from Cleveland Amtrak and arriving at St. Louis Gateway Station Amtrak via Chicago Union Station Amtrak. The journey, including transfers, takes approximately 13 h 16 min.

No, there is no direct bus from Cleveland to St. Louis. However, there are services departing from Cleveland, Oh and arriving at St Louis, Mo via Columbus, Oh. The journey, including transfers, takes approximately 11 h 57 min.

It takes approximately 3 h 42 min to get from Cleveland to St. Louis, including transfers.