There are 11 ways to get from Niagara Falls to Indiana by bus, plane, train, bus (Flixbus), car, bus (Greyhound), or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport, train
best- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane BUF - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
6h$90–554Bus
cheapest- Take the bus from Buffalo, NY to Columbus - Mound Stbus Buffalo
- Take the bus from Columbus to Indianapolisbus FlixBus N2640 / ...
13h 50m$69–140Train, bus
- Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain
- Take the train from Buffalo Depew Station to Toledotrain
- Take the bus from Toledo to Indianapolis, INbus
12h 25m$74–261Drive 512.2 mi
- Drive from Niagara Falls to Indianapoliscar 512.2 mi
9h 2m$94–135Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport, train
- Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
- Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane BUF - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
5h 47m$115–744Train to Toronto Pearson International Airport, fly to Indianapolis
- Take the train from Canadian Border to Torontotrain
- Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane YYZ - IND
7h 17m$213–555Train to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport, train
- Take the train from Canadian Border to Torontotrain
- Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)plane YYZ - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
8h 27m$220–557Train to Toronto Island Airport, fly to Chicago O'Hare International Airport, train
- Take the train from Canadian Border to Torontotrain
- Fly from Toronto Island Airport (YTZ) to Chicago O'Hare International Airport (ORD)plane YTZ - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
8h 19m$233–560Train to Toronto Island Airport, fly to Chicago Midway International Airport, train
- Take the train from Canadian Border to Torontotrain
- Fly from Toronto Island Airport (YTZ) to Chicago Midway International Airport (MDW)plane YTZ - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
8h 6m$173–530Bus via Cleveland (Greyhound)
- Take the bus from Buffalo to Cleveland Bus Stationbus
- Take the bus from Cleveland Bus Station to Dayton Trotwood Bus Stationbus
- Take the bus from Dayton Trotwood Bus Station to Indianapolis Union Stationbus
15h 6m$99–197Train
- Take the train from Niagara Falls Amtrak Station to Buffalo Depew Stationtrain
- Take the train from Buffalo Depew Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Indianapolistrain
18h 13m$113–341
Niagara Falls to Indiana by train and bus
Questions & Answers
The cheapest way to get from Niagara Falls to Indiana is to bus which costs $65 - $140 and takes 13h 50m.
The fastest way to get from Niagara Falls to Indiana is to bus and fly and train which takes 5h 47m and costs $110 - $750.
No, there is no direct bus from Niagara Falls to Indiana. However, there are services departing from Pine Avenue & Main Street and arriving at Indianapolis via Buffalo, NY, S Grant Ave & E Mound St and Columbus. The journey, including transfers, takes approximately 13h 50m.
No, there is no direct train from Niagara Falls station to Indiana. However, there are services departing from Niagara Falls Amtrak Station and arriving at Indianapolis via Buffalo Depew Station and Chicago Union Station. The journey, including transfers, takes approximately 18h 13m.
The distance between Niagara Falls and Indiana is 554 miles. The road distance is 515.2 miles.
The best way to get from Niagara Falls to Indiana without a car is to train and bus which takes 12h 25m and costs $70 - $270.
It takes approximately 6h to get from Niagara Falls to Indiana, including transfers.
Niagara Falls to Indiana bus services, operated by Barons Bus, depart from Buffalo, NY station.
Niagara Falls to Indiana train services, operated by Amtrak, depart from Niagara Falls Amtrak Station.
The best way to get from Niagara Falls to Indiana is to bus which takes 13h 50m and costs $65 - $140. Alternatively, you can train, which costs $110 - $350 and takes 18h 13m.
What companies run services between Niagara Falls, NY, USA and Indiana, USA?
You can take a bus from Pine Avenue & Main Street to Indianapolis via Buffalo, NY, Columbus - Mound St, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 13h 50m. Alternatively, you can take a train from Niagara Falls Amtrak Station to Indianapolis via Buffalo Depew Station and Chicago Union Station in around 18h 13m.
- Website
- united.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $75–460
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $110–600
Flights from Toronto Pearson International Airport to Indianapolis
- Ave. Duration
- 1h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–360
Flights from Toronto Pearson International Airport to Indianapolis via Chicago O'Hare International Airport
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $70–390
Flights from Toronto Pearson International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $40–250
Flights from Toronto Island Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 55m
- When
- Monday to Friday
- Estimated price
- $40–240
Flights from Toronto Island Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 42m
- When
- Monday and Saturday
- Estimated price
- $60–300
- Website
- aircanada.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 6m
- When
- Every day
- Estimated price
- $75–460
Flights from Toronto Pearson International Airport to Indianapolis
- Ave. Duration
- 1h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $60–360
Flights from Toronto Pearson International Airport to Indianapolis via Chicago O'Hare International Airport
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $70–390
Flights from Toronto Pearson International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $40–250
Flights from Toronto Island Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 55m
- When
- Monday to Friday
- Estimated price
- $40–240
Flights from Toronto Island Airport to Chicago O'Hare International Airport via Washington Dulles
- Ave. Duration
- 4h 42m
- When
- Monday and Saturday
- Estimated price
- $60–300
- Website
- aa.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- $75–460
Flights from Toronto Pearson International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $40–250
- Website
- delta.com
Flights from Buffalo Niagara International Airport to Chicago O'Hare International Airport via Detroit
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $80–460
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Detroit
- Ave. Duration
- 3h 49m
- When
- Every day
- Estimated price
- $100–650
Flights from Toronto Pearson International Airport to Indianapolis via Detroit
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $60–360
- Website
- flyporter.com
Flights from Toronto Pearson International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $40–250
Flights from Toronto Island Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 50m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $110–410
- Website
- southwest.com
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport
- Ave. Duration
- 2h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Flights from Buffalo Niagara International Airport to Chicago Midway International Airport via Baltimore
- Ave. Duration
- 4h 22m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $150–800
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Niagara Falls Amtrak Station to Buffalo Depew Station
- Ave. Duration
- 46 min
- Frequency
- 3 times a day
- Estimated price
- $13–15
- Website
- https://www.amtrak.com/home.html
Train from Buffalo Depew Station to Toledo
- Ave. Duration
- 5h 34m
- Frequency
- Twice daily
- Estimated price
- $40–120
- Website
- https://www.amtrak.com/home.html
Train from Canadian Border to Toronto
- Ave. Duration
- 1h 58m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- https://www.amtrak.com/home.html
Train from Buffalo Depew Station to Chicago Union Station
- Ave. Duration
- 10h 33m
- Frequency
- Twice daily
- Estimated price
- $70–200
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888 842-7245
- Website
- viarail.ca
Train from Niagara Falls Amtrak Station to Buffalo Depew Station
- Ave. Duration
- 46 min
- Frequency
- Once daily
- Estimated price
- $13–80
- Website
- https://www.viarail.ca/en
- Economy Adult - same day booking
- $13–80
- Economy Adult - Advanced Booking
- $13–60
- Economy Escape Advanced Booking - Adult
- $13–25
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 55 min
- Frequency
- 5 times a day
- Estimated price
- $6–85
- Schedules at
- flixbus.com
- Adult
- $6–85
Bus from Columbus to Indianapolis
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Schedules at
- flixbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Niagara Falls USA to Buffalo Niagara International Airport
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $20–50
- Website
- https://www.ourbus.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Toledo to Indianapolis, IN
- Ave. Duration
- 4h 5m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- https://baronsbus.com
Bus from Buffalo, NY to Columbus - Mound St
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- https://baronsbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Buffalo to Cleveland Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Dayton Trotwood Bus Station
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
Bus from Dayton Trotwood Bus Station to Indianapolis Union Station
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $30–60
- Website
- https://www.greyhound.com/
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More Questions & Answers
Niagara Falls to Indiana bus services, operated by Barons Bus, arrive at Columbus - Mound St station.
Niagara Falls to Indiana train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Niagara Falls to Indiana is 515 miles. It takes approximately 9h 2m to drive from Niagara Falls to Indiana.
Book your Niagara Falls to Indiana train tickets online with Omio.
There are 805+ hotels available in Indiana.




















