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How to get fromBuffalo to Indianaby plane, train, bus, bus (Greyhound), car, shuttle, bus (Flixbus) or train (Amtrak)

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There are 9 ways to get from Buffalo to Indiana by plane, train, bus, bus (Greyhound), car, shuttle, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Chicago Midway International Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)planeBUF - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain
    4h 52m
    $113–694

  2. Bus

    cheapest
    1. Take the bus from Buffalo, NY to Cincinnati, OHbusBuffalo
    2. Take the bus from Cincinnati Bus Station to Indianapolis Union StationbusGreyhound US0120
    13h 10m
    $64–130

  3. Train, bus

    1. Take the train from Buffalo Depew Station to ToledotrainLake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbusDetroit
    11h 56m
    $100–260

  4. Drive 495.3 mi

    1. Drive from Buffalo to Indianapoliscar495.3 mi
    8h 27m
    $91–131

  5. Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)planeBUF - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain
    5h 14m
    $88–534

  6. Shuttle to Toronto Pearson International Airport, fly to Indianapolis

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle
    2. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)planeYYZ - IND
    7h 30m
    $286–662

  7. Bus to Rochester, fly to Chicago Midway International Airport, train

    1. Take the bus from Buffalo, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)planeROC - MDW
    3. Take the train from Van Buren St. to Gary Metro Centertrain
    7h 7m
    $118–639

  8. Bus via Pittsburgh

    1. Take the bus from Buffalo to PittsburghbusFab530
    2. Take the bus from Pittsburgh Intermodal Station to IndianapolisbusFlixBus N2640
    15h 45m
    $84–270

  9. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union StationtrainLake Shore Limited
    2. Take the train from Chicago Union Station to IndianapolistrainCardinal
    17h 44m
    $104–350

Buffalo to Indiana by train and bus

Calendar7Weekly Services
Duration11h 56mAverage Duration
Ticket$100Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Indiana, USA?

You can take a bus from Buffalo, NY to Indianapolis Union Station via Cincinnati, OH and Cincinnati Bus Station in around 13h 10m. Alternatively, you can take a train from Buffalo to Indianapolis via Buffalo Depew Station and Chicago Union Station in around 17h 44m.

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