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How to get fromBuffalo to Indianaby plane, train, bus, bus (Greyhound), car, shuttle, bus (Flixbus) or train (Amtrak)

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There are 8 ways to get from Buffalo to Indiana by plane, train, bus, bus (Greyhound), car, shuttle, bus (Flixbus), or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Chicago O'Hare International Airport, train

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 20m
    $88–554

  2. Train, bus

    cheapest
    1. Take the train from Buffalo Depew Station to Toledotrain train Lake Shore Limited
    2. Take the bus from Toledo to Indianapolis, INbus bus Detroit
    11h 56m
    $55–259

  3. Bus

    1. Take the bus from Buffalo, NY to Cincinnati, OHbus bus Buffalo
    2. Take the bus from Cincinnati Bus Station to Indianapolis Union Stationbus bus Greyhound US0120
    13h 10m
    $67–130

  4. Drive 495.5 mi

    1. Drive from Buffalo to Indianapoliscar car 495.5 mi
    8h 30m
    $91–131

  5. Fly Buffalo Niagara International Airport to Chicago Midway International Airport, train

    1. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain train
    5h 7m
    $123–794

  6. Shuttle to Toronto Pearson International Airport, fly to Indianapolis

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Indianapolis (IND)plane plane YYZ - IND
    7h 30m
    $266–652

  7. Bus via Pittsburgh

    1. Take the bus from Buffalo to Pittsburghbus bus Fab530
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolisbus bus FlixBus N2640
    15h 45m
    $89–250

  8. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    17h 44m
    $114–339

Buffalo to Indiana by train and bus

Calendar7Weekly Services
Duration11h 56mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Indiana, USA?

You can take a bus from Buffalo, NY to Indianapolis Union Station via Cincinnati, OH and Cincinnati Bus Station in around 13h 10m. Alternatively, you can take a train from Buffalo to Indianapolis via Buffalo Depew Station and Chicago Union Station in around 17h 44m.

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