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How to get fromSt. Louis to Indianaby bus (Greyhound), train (Amtrak), car, plane, train or bus (Flixbus)

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There are 6 ways to get from St. Louis to Indiana by bus (Greyhound), train (Amtrak), car, plane, train, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from St Louis Bus Station to Indianapolis Union StationbusGreyhound US0421
    4h 25m
    $35–85

  2. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union StationtrainLincoln Service / ...
    2. Take the train from Chicago Union Station to IndianapolistrainCardinal
    10h 49m
    $72–389

  3. Drive 241.2 mi

    1. Drive from St. Louis to Indianapoliscar241.2 mi
    4h 1m
    $44–64

  4. Fly to Chicago Midway International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)planeSTL - MDW
    2. Take the train from Van Buren St. to Gary Metro Centertrain
    4h 28m
    $82–496

  5. Bus via Champaign

    1. Take the bus from St Louis Bus Station to Champaign Intermodal Trans CtrbusFlixBus N2521 / ...
    2. Take the bus from Champaign to Indianapolis Union StationbusDenver
    6h 35m
    $67–135

  6. Fly to Chicago O'Hare International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)planeSTL - ORD
    2. Take the train from Van Buren St. to Gary Metro Centertrain
    4h 57m
    $182–516

St. Louis to Indiana by bus (Greyhound)

Calendar21Weekly Buses
Duration4h 25mAverage Duration
Ticket$35Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Indiana, USA?

Greyhound USA operates a bus from St Louis Bus Station to Indianapolis Union Station 3 times a day. Tickets cost $35–85 and the journey takes 4h 25m. Alternatively, you can take a train from St. Louis to Indianapolis via Chicago Union Station in around 10h 49m.

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