There are 5 ways to get from St. Louis to Indiana by bus (Greyhound), train (Amtrak), car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Greyhound)
best- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus Greyhound US0421
4h 25m$30–65Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
10h 49m$71–337Drive 241.2 mi
- Drive from St. Louis to Indianapoliscar 241.2 mi
4h 3m$44–64Fly to Chicago Midway International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
- Take the train from Van Buren St. to Gary Metro Centertrain
4h 28m$86–566Fly to Chicago O'Hare International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
- Take the train from Van Buren St. to Gary Metro Centertrain
4h 53m$212–506
St. Louis to Indiana by bus (Greyhound)
Questions & Answers
The cheapest way to get from St. Louis to Indiana is to bus which costs $30 - $65 and takes 4h 25m.
The fastest way to get from St. Louis to Indiana is to drive which takes 4h 3m and costs $40 - $65.
Yes, there is a direct bus departing from St Louis Bus Station station and arriving at Indianapolis Union Station station. Services depart three times a day, and operate every day. The journey takes approximately 4h 25m.
No, there is no direct train from St. Louis to Indiana. However, there are services departing from St. Louis and arriving at Indianapolis via Chicago Union Station. The journey, including transfers, takes approximately 10h 49m.
The distance between St. Louis and Indiana is 243 miles. The road distance is 242.6 miles.
The best way to get from St. Louis to Indiana without a car is to bus which takes 4h 25m and costs $30 - $65.
The bus from St Louis Bus Station to Indianapolis, Illinois St (Greyhound Bus Station) takes 4h 25m including transfers and departs three times a day.
St. Louis to Indiana bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Indiana train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Indiana is to bus which takes 4h 25m and costs $30 - $65. Alternatively, you can train, which costs $70 - $340 and takes 10h 49m.
What companies run services between St. Louis, MO, USA and Indiana, USA?
Greyhound USA operates a bus from St Louis Bus Station to Indianapolis Union Station 3 times a day. Tickets cost $30–65 and the journey takes 4h 25m. Alternatively, you can take a train from St. Louis to Indianapolis via Chicago Union Station in around 10h 49m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $75–550
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $50–370
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $50–370
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $50–370
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $40–280
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Van Buren St. to Gary Metro Center
- Ave. Duration
- 46 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 25m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
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More Questions & Answers
St. Louis to Indiana bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Indiana is 1h ahead of St. Louis. It is currently 10:35 PM in St. Louis and 11:35 PM in Indiana.
St. Louis to Indiana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Indiana is 243 miles. It takes approximately 4h 3m to drive from St. Louis to Indiana.
Book your St. Louis to Indiana train tickets online with Omio.
Book your St. Louis to Indiana bus tickets online with Omio and FlixBus.
There are 673+ hotels available in Indiana.