There are 7 ways to get from Natchez to St. Louis by plane, car, train, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Natchez
best- Fly from Natchez (HEZ) to Lambert–St. Louis International Airport (STL)plane HEZ - STL
8h 20m$191–836Drive, train, bus via Carbondale
cheapest- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Carbondaletrain
- Take the bus from Carbondale to St. Louisbus
15h 44m$83–222Drive, train, bus
- Drive from Natchez to Brookhaven Stationcar
- Take the train from Brookhaven Station to Jacksontrain
- Take the bus from Jackson to St Louis Bus Stationbus
14h 6m$104–254Drive 571.8 mi
- Drive from Natchez to St. Louiscar 571.8 mi
10h 28m$105–151Drive to Baton Rouge Metropolitan Airport, fly
- Drive from Natchez to Baton-Rouge-Airport-BTRcar
- Fly from Baton Rouge Metropolitan Airport (BTR) to Lambert–St. Louis International Airport (STL)plane BTR - STL
6h 43m$168–825Taxi to Alexandria International Airport, fly
- Take the taxi from Natchez to Alexandria International Airport (AEX)taxi
- Fly from Alexandria International Airport (AEX) to Lambert–St. Louis International Airport (STL)plane AEX - STL
7h 3m$165–829Taxi to Monroe Regional Airport, fly
- Take the taxi from Natchez to Monroe Regional Airport (MLU)taxi
- Fly from Monroe Regional Airport (MLU) to Lambert–St. Louis International Airport (STL)plane MLU - STL
7h 17m$175–829
Natchez (HEZ) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Natchez to St. Louis is to drive which costs $100 - $160 and takes 10h 28m.
The fastest way to get from Natchez to St. Louis is to drive and fly which takes 6h 43m and costs $160 - $850.
The distance between Natchez and St. Louis is 522 miles. The road distance is 575.1 miles.
It takes approximately 8h 20m to get from Natchez to St. Louis, including transfers.
Yes, the driving distance between Natchez to St. Louis is 575 miles. It takes approximately 10h 28m to drive from Natchez to St. Louis.
There are 437+ hotels available in St. Louis.
What companies run services between Natchez, MS, USA and St. Louis, MO, USA?
United Airlines and Southwest Airlines fly from Natchez (HEZ) to Lambert–St. Louis International Airport (STL) once daily.
- Website
- aa.com
Flights from Baton Rouge Metropolitan Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $160–800
Flights from Baton Rouge Metropolitan Airport to Lambert–St. Louis International Airport via Charlotte
- Ave. Duration
- 5h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, and Saturday
- Estimated price
- $190–950
Flights from Alexandria International Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $140–800
Flights from Monroe Regional Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $150–800
- Website
- delta.com
Flights from Baton Rouge Metropolitan Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 4h 23m
- When
- Every day
- Estimated price
- $160–800
Flights from Alexandria International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 50m
- When
- Every day
- Estimated price
- $160–850
Flights from Monroe Regional Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $150–800
- Website
- united.com
Flights from Natchez to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $160–800
Flights from Baton Rouge Metropolitan Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $150–800
- Website
- southwest.com
Flights from Natchez to Lambert–St. Louis International Airport via Houston, New Orleans
- Ave. Duration
- 7h 32m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–900
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Brookhaven Station to Jackson
- Ave. Duration
- 1h 32m
- Frequency
- Once daily
- Estimated price
- $22–27
- Website
- https://www.amtrak.com/home.html
Train from Brookhaven Station to Carbondale
- Ave. Duration
- 11h 15m
- Frequency
- Once daily
- Estimated price
- $50–170
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $50–130
- Coach Seat short notice purchase
- $60–170
- Business - advance purchase
- $85–370
- Business Class
- $140–390
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Jackson to St Louis Bus Station
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $70–210
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Carbondale to St. Louis
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $21–35
- Schedules at
- flixbus.com
- Ave. Duration
- 1h 56m
- Estimated price
- $22–26
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