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How to get fromMinnesota to St. Louisby plane, train (Amtrak), bus (Greyhound, Flixbus), car or bus

Find Transport to St. Louis

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There are 7 ways to get from Minnesota to St. Louis by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Minneapolis–Saint Paul International Airport

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)planeMSP - STL
    3h 35m
    $385–756

  2. Bus

    cheapest
    1. Take the bus from Minneapolis Bus Station to Chicago Bus StationbusGreyhound US0150 / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus StationbusFlixBus N2521 / ...
    15h 30m
    $84–218

  3. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union StationtrainBorealis / ...
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    14h 32m
    $112–442

  4. Drive 531.6 mi

    1. Drive from Minneapolis to St. Louiscar531.6 mi
    9h 38m
    $97–141

  5. Fly from Rochester

    1. Fly from Rochester (RST) to Lambert–St. Louis International Airport (STL)planeRST - STL
    5h 38m
    $99–590

  6. Fly from Duluth International Airport

    1. Fly from Duluth International Airport (DLH) to Lambert–St. Louis International Airport (STL)planeDLH - STL
    6h 54m
    $104–604

  7. Bus via Des Moines

    1. Take the bus from Minneapolis to Des Moinesbus
    2. Take the bus from Des Moines to Mt. Pleasantbus
    3. Take the bus from Mt. Pleasant to St Louisbus
    15h 50m
    $122–320

Minnesota to St. Louis by bus and train (Amtrak)

Calendar21Weekly Services
Duration14h 32mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

What companies run services between Minnesota, USA and St. Louis, MO, USA?

Delta, Southwest Airlines, and United Airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from 6th St S & 5th Ave S to St. Louis via Union Depot Station & Terminal, St. Paul-Minneapolis, and Chicago Union Station in around 14h 32m.

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