Rome2Rio

How to get fromMinnesota to St. Louisby plane, bus (Greyhound), train (Amtrak) or car

Find Transport to St. Louis

See all options

There are 6 ways to get from Minnesota to St. Louis by plane, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Minneapolis–Saint Paul International Airport

    best
    1. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane plane MSP - STL
    3h 32m
    $116–757

  2. Drive 531.6 mi

    cheapest
    1. Drive from Minneapolis to St. Louiscar car 531.6 mi
    9h 41m
    $97–141

  3. Bus

    1. Take the bus from Minneapolis to Des Moinesbus bus Jefferson 801 / ...
    2. Take the bus from Des Moines to St Louis Bus Stationbus bus Greyhound US0153S
    14h 15m
    $130–219

  4. Train (Amtrak)

    1. Take the train from St. Paul-Minneapolis to Chicago Union Stationtrain train Borealis / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    14h 32m
    $187–422

  5. Fly from Rochester

    1. Fly from Rochester (RST) to Lambert–St. Louis International Airport (STL)plane plane RST - STL
    5h 44m
    $104–690

  6. Fly from Duluth International Airport

    1. Fly from Duluth International Airport (DLH) to Lambert–St. Louis International Airport (STL)plane plane DLH - STL
    5h 48m
    $114–654

Minnesota to St. Louis by bus

Calendar7Weekly Buses
Duration14h 15mAverage Duration
Ticket$130Cheapest Price
See schedules

Questions & Answers

What companies run services between Minnesota, USA and St. Louis, MO, USA?

Delta, Southwest Airlines, and United Airlines fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL) every 2 hours. Alternatively, you can take a bus from Minneapolis to St Louis Bus Station via Des Moines in around 14h 15m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Minnesota

Trips to St. Louis

Popular routes