There are 6 ways to get from Niagara Falls to St. Louis by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Buffalo  •  7 h 1 min

  1. Fly from Buffalo (BUF) to St. Louis (STL) BUF - STL

$187 - $432

Cheapest option

Bus via Columbus, Oh  •  18 h 21 min

  1. Take the bus from Buffalo, NY to Columbus, OH Buffalo
  2. Take the bus from Columbus, Oh to St Louis, Mo 1683 / ...

$72 - $202

4 alternative options

Train to Toronto, fly  •  7 h 11 min

  1. Take the train from Niagara Falls to Toronto
  2. Fly from Toronto (YYZ) to St. Louis (STL) YYZ - STL

$208 - $568

Train  •  18 h 52 min

  1. Take the train from Niagara Falls Station to Buffalo
  2. Take the train from Buffalo Depew Station Amtrak to Chicago Union Station
  3. Take the train from Chicago Union Station to St. Louis Gateway Station

$147 - $408

Bus Greyhound Canada  •  20 h 57 min

  1. Take the bus from Niagara Falls, On to Toronto, On 252 / ...
  2. Take the bus from Toronto, ON to Chicago, IL
  3. Take the bus from Chicago, IL to St. Louis

$92 - $200

Drive  •  12 h 57 min

  1. Drive from Niagara Falls to St. Louis 766.4 miles

$75 - $110

Questions & Answers

No, there is no direct bus from Niagara Falls to St. Louis. However, there are services departing from Main St & Walnut Ave and arriving at St Louis, Mo via Buffalo, NY and Columbus, Oh. The journey, including transfers, takes approximately 18 h 21 min.

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No, there is no direct train from Niagara Falls station to St. Louis station. However, there are services departing from Niagara Falls Station and arriving at St. Louis Gateway Station via Buffalo Depew Station Amtrak and Chicago Union Station. The journey, including transfers, takes approximately 18 h 52 min.

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The distance between Niagara Falls and St. Louis is 662 miles. The road distance is 766.4 miles.

Get driving directions

The best way to get from Niagara Falls to St. Louis without a car is to bus which takes 18 h 21 min and costs .

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It takes approximately 7 h 1 min to get from Niagara Falls to St. Louis, including transfers.

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Niagara Falls to St. Louis bus services, operated by Barons Bus, depart from Buffalo, NY station.

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Niagara Falls to St. Louis train services, operated by VIA Rail, arrive at Niagara Falls Station.

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The best way to get from Niagara Falls to St. Louis is to fly which takes 7 h 1 min and costs . Alternatively, you can bus, which costs and takes 18 h 21 min, you could also train, which costs and takes 18 h 52 min.

Mode details

There is no direct flight from Buffalo Airport to St. Louis Airport. The quickest flight takes 4 h and has one stopover.

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Niagara Falls to St. Louis bus services, operated by Greyhound USA, arrive at St Louis, Mo station.

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Map of how to get from Niagara Falls to St. Louis.
Launch map view
  • Distance: 662 miles
  • Duration: 7 h 1 min

What companies run services between Niagara Falls, NY, USA and St. Louis, MO, USA?

American Airlines, Southwest Airlines and two other airlines fly from Niagara Falls to St. Louis hourly. Alternatively, you can take a bus from Niagara Falls to St. Louis via Ellicott St & MTC, Buffalo, NY, Columbus, OH, and Columbus, Oh in around 18 h 21 min.

Airlines
United Airlines
Website
united.com
Flights from Buffalo to St. Louis via Chicago O'Hare
Ave. Duration
4 h 18 min
When
Every day
Estimated price
$190 - $850
Flights from Buffalo to St. Louis via Washington Dulles
Ave. Duration
4 h 45 min
When
Every day
Estimated price
$190 - $850
Flights from Toronto to St. Louis
Ave. Duration
2 h 6 min
When
Every day
Estimated price
$210 - $2,400
Flights from Toronto to St. Louis via Chicago O'Hare
Ave. Duration
4 h 27 min
When
Every day
Estimated price
$220 - $1,100
Flights from Toronto to St. Louis via Washington Dulles
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$220 - $1,100
American Airlines
Website
aa.com
Flights from Buffalo to St. Louis via Chicago O'Hare
Ave. Duration
4 h 22 min
When
Every day
Estimated price
$180 - $700
Flights from Buffalo to St. Louis via Reagan Washington
Ave. Duration
4 h 42 min
When
Every day
Estimated price
$180 - $700
Flights from Buffalo to St. Louis via Charlotte
Ave. Duration
4 h 40 min
When
Monday to Friday
Estimated price
$180 - $700
Flights from Toronto to St. Louis via Chicago O'Hare
Ave. Duration
4 h 16 min
When
Every day
Estimated price
$210 - $1,100
Flights from Toronto to St. Louis via Philadelphia
Ave. Duration
4 h 57 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,100
Flights from Toronto to St. Louis via Charlotte
Ave. Duration
4 h 59 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,100
Air Canada
Website
aircanada.com
Flights from Buffalo to St. Louis via Chicago O'Hare
Ave. Duration
4 h 18 min
When
Every day
Estimated price
$190 - $850
Flights from Toronto to St. Louis
Ave. Duration
2 h 6 min
When
Every day
Estimated price
$210 - $2,400
Flights from Toronto to St. Louis via Chicago O'Hare
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$220 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Buffalo to St. Louis via Chicago Midway
Ave. Duration
4 h 15 min
When
Every day
Estimated price
$330 - $950
Flights from Buffalo to St. Louis via Baltimore
Ave. Duration
4 h 30 min
When
Monday to Saturday
Estimated price
$330 - $950
Delta
Website
delta.com
Flights from Buffalo to St. Louis via Detroit
Ave. Duration
4 h 14 min
When
Monday to Friday
Estimated price
$180 - $700
Flights from Buffalo to St. Louis via Atlanta
Ave. Duration
4 h 51 min
When
Monday to Friday
Estimated price
$180 - $700
Flights from Buffalo to St. Louis via Minneapolis
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$180 - $700
Flights from Toronto to St. Louis via Detroit
Ave. Duration
4 h 9 min
When
Monday to Saturday
Estimated price
$220 - $1,100
Train operators
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Niagara Falls to Toronto
Ave. Duration
1 h 56 min
Frequency
Every 3 hours
Estimated price
$26 - $75
Website
viarail.ca
Escape
$26 - $40
Economy
$35 - $50
Economy Plus
$55 - $75
Business
$45 - $70
Business Plus/Sleeper
$90 - $130
Train from Niagara Falls Station to Buffalo
Ave. Duration
52 min
Frequency
Every 3 hours
Estimated price
$21 - $60
Website
viarail.ca
Escape
$21 - $30
Economy
$25 - $35
Economy Plus
$40 - $60
Business
$35 - $50
Business Plus/Sleeper
$65 - $90
GO Transit
Phone
+1 888-438-6646
Website
gotransit.com
Train from Niagara Falls GO to Union Station
Ave. Duration
2 h 4 min
Frequency
5 times a week
Estimated price
$11 - $15
Website
GO Transit
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Niagara Falls Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
52 min
Frequency
3 times a day
Estimated price
$22 - $45
Website
amtrak.com
Coach Seat
$22 - $35
Flexi Coach Seat
$35 - $60
Business Coach Seat
$29 - $45
Room
$130 - $190
Train from Buffalo Depew Station Amtrak to Chicago Union Station
Ave. Duration
10 h 30 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Train from Chicago Union Station to St. Louis Gateway Station
Ave. Duration
5 h 30 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Columbus, Oh to St Louis, Mo
Ave. Duration
9 h 10 min
Frequency
Every 30 minutes
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Niagara Falls, On to Toronto, On
Ave. Duration
2 h 5 min
Frequency
Every 30 minutes
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40
Megabus Canada
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Chicago, IL
Ave. Duration
10 h 45 min
Frequency
4 times a day
Estimated price
$45 - $120
Website
Greyhound.ca
Advanced Purchase
$45 - $70
Online Fare
$60 - $90
Standard Fare
$75 - $120
Refundable
$85 - $130

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More Questions & Answers

St. Louis is 1 h behind Niagara Falls. It is currently 7:27 AM in Niagara Falls and 6:27 AM in St. Louis.

Niagara Falls to St. Louis train services, operated by Amtrak, arrive at St. Louis Gateway Station.

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Yes, the driving distance between Niagara Falls to St. Louis is 766 miles. It takes approximately 12 h 57 min to drive from Niagara Falls to St. Louis.

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Delta, Southwest Airlines, American Airlines and United Airlines offer flights from Buffalo Airport to St. Louis Airport.

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There are 193+ hotels available in St. Louis. Prices start at $70 USD per night.

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