There are 6 ways to get from Milwaukee to Independence by plane, bus, train (Amtrak), car, train, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly General Mitchell International Airport to Kansas City, line 24 bus
best- Fly from General Mitchell International Airport (MKE) to Kansas City (MCI)plane MKE - MCI
- Take the bus from East Village - Bay A to On White Oak At Osage Ebbus
6h 13m$132–852Drive 544.2 mi
cheapest- Drive from Milwaukee to Independencecar 544.2 mi
9h 39m$100–144Train (Amtrak)
- Take the train from Milwaukee to Chicago Union Stationtrain Hiawatha Service / ...
- Take the train from Chicago Union Station to Independence Stationtrain Lincoln Service Missouri River Runner
12h 50m$174–391Bus to Chicago O'Hare International Airport, fly to Kansas City
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)plane ORD - MCI
7h 53m$299–592Train, subway to Chicago Midway International Airport, fly to Kansas City, line 24 bus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the subway from LaSalle/Van Buren to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane MDW - MCI
- Take the bus from East Village - Bay A to On White Oak At Osage Ebbus
8h 18m$116–656Bus to Chicago O'Hare International Airport, fly to Manhattan Regional Airport, drive
- Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
- Fly from Chicago O'Hare International Airport (ORD) to Manhattan Regional Airport (MHK)plane ORD - MHK
- Drive from Manhattan Regional Airport (MHK) to Independencecar
7h 9m$108–372
Milwaukee to Independence by train (Amtrak)
Questions & Answers
The cheapest way to get from Milwaukee to Independence is to drive which costs $95 - $150 and takes 9h 39m.
The fastest way to get from Milwaukee to Independence is to fly and line 24 bus which takes 6h 13m and costs $130 - $850.
No, there is no direct train from Milwaukee to Independence station. However, there are services departing from Milwaukee and arriving at Independence Station via Chicago Union Station. The journey, including transfers, takes approximately 12h 50m.
The distance between Milwaukee and Independence is 482 miles. The road distance is 547.4 miles.
The best way to get from Milwaukee to Independence without a car is to train which takes 12h 50m and costs $170 - $400.
It takes approximately 6h 13m to get from Milwaukee to Independence, including transfers.
Milwaukee to Independence train services, operated by Amtrak, depart from Milwaukee station.
Milwaukee to Independence train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Milwaukee to Independence is 547 miles. It takes approximately 9h 39m to drive from Milwaukee to Independence.
Book your Milwaukee to Independence train tickets online with Omio.
What companies run services between Milwaukee, WI, USA and Independence, MO, USA?
You can take a train from Milwaukee to Independence Station via Chicago Union Station in around 12h 50m.
- Website
- southwest.com
Flights from General Mitchell International Airport to Kansas City
- Ave. Duration
- 1h 31m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–850
Flights from General Mitchell International Airport to Kansas City via St. Louis
- Ave. Duration
- 3h 15m
- When
- Sunday
- Estimated price
- $150–900
Flights from Chicago Midway International Airport to Kansas City
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $90–600
Flights from Chicago Midway International Airport to Kansas City via St. Louis
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago Midway International Airport to Kansas City via Indianapolis
- Ave. Duration
- 3h 45m
- When
- Monday, Tuesday, Thursday, and Friday
- Estimated price
- $110–650
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $60–390
Flights from Chicago O'Hare International Airport to Manhattan Regional Airport
- Ave. Duration
- 1h 58m
- When
- Every day
- Estimated price
- $45–290
- Website
- united.com
Flights from General Mitchell International Airport to Kansas City via Chicago O'Hare International Airport
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $140–850
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $60–390
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Kansas City via Minneapolis
- Ave. Duration
- 4h 15m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–480
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–55
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Independence Station
- Ave. Duration
- 10h 21m
- Frequency
- Once daily
- Estimated price
- $150–340
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from LaSalle/Van Buren to Midway
- Ave. Duration
- 33 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
- Phone
- +1 816-221-0660
- Website
- ridekc.org
Bus from East Village - Bay A to On White Oak At Osage Eb
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Schedules at
- ridekc.org
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departures
- Ave. Duration
- 1h 50m
- Frequency
- Hourly
- Estimated price
- $38–42
- Schedules at
- coachusa.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 240+ hotels available in Independence.









