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How to get fromMilwaukee to Defianceby train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, bus, plane, taxi, or bus (Amtrak)

Find Transport to Defiance

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There are 5 ways to get from Milwaukee to Defiance by train (Amtrak), bus (Greyhound, Flixbus, Amtrak), car, bus, plane, taxi, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to Bryan Amtrak Stationtrain train Lake Shore Limited
    6h 12m
    $129–232

  2. Drive 285.1 mi

    cheapest
    1. Drive from Milwaukee to Defiancecar car 285.1 mi
    6h 1m
    $52–76

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus Greyhound US0150S / ...
    2. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    6h 37m
    $127–193

  4. Bus, fly, taxi

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Fort Wayne International Airport (FWA)plane plane ORD - FWA
    3. Take the taxi from Fort Wayne International Airport (FWA) to Defiancetaxi taxi
    5h 7m
    $208–471

  5. Bus via Chicago O'Hare Airport (ORD)

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus Wisconsin Coach Lines
    2. Take the bus from Chicago Union Station to Bryan Amtrak Stationbus bus Amtrak Thruway Connecting Service
    7h 35m
    $155–211

Chicago O'Hare International Airport (ORD) to Fort Wayne International Airport (FWA) flights

Calendar62Weekly Planes
Duration1h 15mAverage Duration
Ticket$30Cheapest Price
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Questions & Answers

What companies run services between Milwaukee, WI, USA and Defiance, OH, USA?

You can take a train from Milwaukee to Defiance via Chicago Union Station and Bryan Amtrak Station in around 6h 12m. Alternatively, you can take a bus from Milwaukee Intermodal Station to Defiance via Chicago Bus Station, Chicago Union Station, and Bryan Amtrak Station in around 6h 37m.

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Need to know: Greyhound

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