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How to get fromPittsburgh to Independenceby bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, train or bus (Greyhound)

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There are 7 ways to get from Pittsburgh to Independence by bus, plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Pittsburgh International Airport, fly to Kansas City, line 24 bus

    best
    1. Take the bus from Seventh Ave + Smithfield St to Pittsburgh International Airportbus bus
    2. Fly from Pittsburgh International Airport (PIT) to Kansas City (MCI)plane plane PIT - MCI
    3. Take the bus from East Village - Bay A to On White Oak At Osage Ebbus bus
    9h 46m

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Pittsburgh Intermodal Station to Indianapolisbus bus FlixBus N2640
    2. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus Greyhound US0421D
    20h 32m
    $103–215

  3. Train (Amtrak)

    1. Take the train from Pittsburgh Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the train from Chicago Union Station to Independence Stationtrain train Lincoln Service Missouri River Runner
    21h 7m
    $129–272

  4. Drive 831 mi

    1. Drive from Pittsburgh to Independencecar car 831 mi
    14h 8m
    $152–220

  5. Train to Cleveland-Hopkins International Airport, fly to Kansas City

    1. Take the train from Pittsburgh Amtrak Station to Cleveland Amtraktrain train
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Kansas City (MCI)plane plane CLE - MCI
    12h 16m
    $151–748

  6. Fly Pittsburgh International Airport to Lambert–St. Louis International Airport, train

    1. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    2. Take the train from St. Louis to Independence Stationtrain train
    11h 10m
    $405–882

  7. Bus (Greyhound)

    1. Take the bus from Pittsburgh Intermodal Station to Indianapolis Union Stationbus bus Greyhound US0421 / ...
    2. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus Greyhound US0421D
    20h 53m
    $105–255

Pittsburgh to Independence by bus and foot

Calendar2Weekly Services
Duration20h 32mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

What companies run services between Pittsburgh, PA, USA and Independence, MO, USA?

You can take a bus from Pittsburgh Intermodal Station to On White Oak At Osage Eb via Indianapolis, Indianapolis Union Station, Kansas City Bus Station, and East Village - Bay A in around 20h 32m. Alternatively, you can take a train from Pittsburgh Amtrak Station to Independence Station via Chicago Union Station in around 21h 7m.

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