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There are 7 ways to get from San Diego to Buffalo by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Buffalo  •  8 h 3 min

  1. Fly from San Diego (SAN) to Buffalo (BUF) SAN - BUF

$194 - $344

Cheapest option

Fly to Toronto, bus  •  10 h 6 min

  1. Fly from San Diego (SAN) to Toronto (YYZ) SAN - YYZ
  2. Take the bus from Toronto, ON to Buffalo, NY

$160 - $406

5 alternative options

Fly to Rochester, train  •  11 h 1 min

  1. Fly from San Diego (SAN) to Rochester (ROC) SAN - ROC
  2. Take the train from Rochester Amtrak Station to Buffalo Amtrak Station

$239 - $608

Train  •  2 days 10 h

  1. Take the train from San Diego Santa Fe Depot to Fullerton Amtrak Station
  2. Take the train from Fullerton Amtrak Station to Chicago Union Station
  3. Take the train from Chicago Union Station to Buffalo Depew Station

$394 - $1,170

Bus  •  2 days 18 h

  1. Take the bus from San Diego, Ca to Los Angeles, Ca
  2. Take the bus from Los Angeles, Ca to Pittsburgh, Pa
  3. Take the bus from Pittsburgh, Pa to Erie, Pa
  4. Take the bus from Erie, Pa to Buffalo, Ny 212

$272 - $726

Bus, train, Thru-Bus  •  3 days 6 h

  1. Take the bus from San Diego to Yuma
  2. Take the train from Yuma Amtrak to Chicago Union Station
  3. Take the bus from Chicago, IL to Hamilton, ON
  4. Take the Thru-Bus from Hamilton, ON to Buffalo, NY

$397 - $1,108

Drive  •  41 h 20 min

  1. Drive from San Diego to Buffalo 2604.7 miles

$250 - $370

Questions & Answers

The cheapest way to get from San Diego to Buffalo is to fly and bus which costs $160 - $410 and takes 10 h 6 min.

More details

The quickest way to get from San Diego to Buffalo is to fly which costs $190 - $350 and takes 8 h 3 min.

More details

No, there is no direct bus from San Diego to Buffalo. However, there are services departing from San Diego, Ca and arriving at Buffalo, Ny via Los Angeles, Ca, Pittsburgh, Pa and Erie, Pa. The journey, including transfers, takes approximately 2 days 18 h.

More details

No, there is no direct train from San Diego to Buffalo station. However, there are services departing from San Diego Santa Fe Depot and arriving at Buffalo Amtrak Station via Fullerton Amtrak Station, Chicago Union Station and Buffalo Depew Station. The journey, including transfers, takes approximately 2 days 10 h.

More details

The distance between San Diego and Buffalo is 2196 miles. The road distance is 2604.7 miles.

Get driving directions

The best way to get from San Diego to Buffalo without a car is to train which takes 2 days 10 h and costs $390 - $1,200.

More details

It takes approximately 8 h 3 min to get from San Diego to Buffalo, including transfers.

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San Diego to Buffalo bus services, operated by Greyhound USA, depart from San Diego, Ca station.

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San Diego to Buffalo train services, operated by Amtrak, depart from San Diego Santa Fe Depot station.

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The best way to get from San Diego to Buffalo is to fly which takes 8 h 3 min and costs $190 - $350. Alternatively, you can train, which costs $390 - $1,200 and takes 2 days 10 h, you could also bus, which costs $270 - $750 and takes 2 days 18 h.

Mode details

Map of how to get from San Diego to Buffalo.
Launch map view
  • Distance: 2196.2 miles
  • Duration: 8 h 3 min

What companies run services between San Diego, CA, USA and Buffalo, NY, USA?

Southwest Airlines, American Airlines and three other airlines fly from San Diego to Buffalo hourly. Alternatively, you can take a train from San Diego to Buffalo via Fullerton Amtrak Station, Chicago Union Station, and Buffalo Depew Station in around 2 days 10 h.

Airlines
United Airlines
Website
united.com
Flights from San Diego to Buffalo via Chicago O'Hare
Ave. Duration
6 h 56 min
When
Every day
Estimated price
$200 - $420
Flights from San Diego to Buffalo via Washington Dulles
Ave. Duration
7 h 30 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$200 - $420
Flights from San Diego to Toronto
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$190 - $650
Flights from San Diego to Toronto via Chicago O'Hare
Ave. Duration
6 h 49 min
When
Every day
Estimated price
$190 - $800
Flights from San Diego to Toronto via Denver
Ave. Duration
7 h
When
Saturday
Estimated price
$190 - $800
Flights from San Diego to Toronto via Washington Dulles
Ave. Duration
7 h 32 min
When
Every day
Estimated price
$190 - $800
Flights from San Diego to Toronto via Houston
Ave. Duration
7 h 34 min
When
Monday, Tuesday, Thursday, Friday, Saturday and Sunday
Estimated price
$190 - $800
Flights from San Diego to Rochester via Chicago O'Hare
Ave. Duration
6 h 51 min
When
Every day
Estimated price
$300 - $850
Flights from San Diego to Rochester via Washington Dulles
Ave. Duration
8 h 13 min
When
Every day
Estimated price
$300 - $850
Flights from San Diego to Rochester via Newark
Ave. Duration
8 h 43 min
When
Every day
Estimated price
$300 - $850
Southwest Airlines
Website
southwest.com
Flights from San Diego to Buffalo via Chicago Midway
Ave. Duration
6 h 37 min
When
Every day
Estimated price
$300 - $490
Flights from San Diego to Buffalo via Las Vegas
Ave. Duration
6 h 56 min
When
Every day
Estimated price
$300 - $490
Flights from San Diego to Buffalo via Phoenix
Ave. Duration
6 h 40 min
When
Every day
Estimated price
$300 - $490
Flights from San Diego to Buffalo via Baltimore
Ave. Duration
7 h 6 min
When
Every day
Estimated price
$300 - $490
Flights from San Diego to Rochester via Baltimore
Ave. Duration
7 h 8 min
When
Every day
Estimated price
$420 - $900
American Airlines
Website
aa.com
Flights from San Diego to Buffalo via Chicago O'Hare
Ave. Duration
6 h 56 min
When
Every day
Estimated price
$200 - $470
Flights from San Diego to Buffalo via Dallas/Ft.Worth
Ave. Duration
6 h 53 min
When
Every day
Estimated price
$200 - $470
Flights from San Diego to Toronto via Chicago O'Hare
Ave. Duration
6 h 52 min
When
Every day
Estimated price
$160 - $450
Flights from San Diego to Rochester via Chicago O'Hare
Ave. Duration
6 h 59 min
When
Every day
Estimated price
$390 - $800
Flights from San Diego to Rochester via Philadelphia
Ave. Duration
8 h 7 min
When
Every day
Estimated price
$390 - $800
Flights from San Diego to Rochester via Charlotte
Ave. Duration
9 h 18 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$390 - $800
Delta
Website
delta.com
Flights from San Diego to Buffalo via Detroit
Ave. Duration
6 h 47 min
When
Every day
Estimated price
$270 - $450
Flights from San Diego to Buffalo via Atlanta
Ave. Duration
7 h 18 min
When
Every day
Estimated price
$270 - $450
Flights from San Diego to Toronto via Minneapolis
Ave. Duration
6 h 39 min
When
Monday, Friday and Sunday
Estimated price
$250 - $850
Flights from San Diego to Toronto via Salt Lake City
Ave. Duration
6 h 50 min
When
Every day
Estimated price
$250 - $850
Flights from San Diego to Toronto via Detroit
Ave. Duration
7 h 3 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $850
Flights from San Diego to Toronto via Atlanta
Ave. Duration
7 h 21 min
When
Every day
Estimated price
$250 - $850
Flights from San Diego to Rochester via Atlanta
Ave. Duration
9 h 16 min
When
Every day
Estimated price
$330 - $850
Flights from San Diego to Rochester via Detroit
Ave. Duration
8 h 52 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $850
Flights from San Diego to Rochester via Minneapolis
Ave. Duration
9 h 23 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $850
Air Canada
Website
aircanada.com
Flights from San Diego to Buffalo via Chicago O'Hare
Ave. Duration
6 h 56 min
When
Every day
Estimated price
$200 - $420
Flights from San Diego to Toronto
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$190 - $650
Flights from San Diego to Toronto via Chicago O'Hare
Ave. Duration
6 h 46 min
When
Every day
Estimated price
$190 - $800
Flights from San Diego to Toronto via Denver
Ave. Duration
7 h
When
Saturday
Estimated price
$190 - $800
Flights from San Diego to Rochester via Chicago O'Hare
Ave. Duration
6 h 51 min
When
Every day
Estimated price
$300 - $850
JetBlue Airways
Website
jetblue.com
Flights from San Diego to Rochester via New York JFK
Ave. Duration
8 h 40 min
When
Every day
Estimated price
$210 - $950
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Rochester Amtrak Station to Buffalo Amtrak Station
Ave. Duration
1 h 17 min
Frequency
3 times a day
Estimated price
$26 - $55
Website
amtrak.com
Coach Seat
$26 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$140 - $210
Train from San Diego Santa Fe Depot to Fullerton Amtrak Station
Ave. Duration
2 h 22 min
Frequency
Every 2 hours
Estimated price
$30 - $65
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$50 - $80
Business Coach Seat
$45 - $65
Room
$160 - $220
Train from Fullerton Amtrak Station to Chicago Union Station
Ave. Duration
42 h 15 min
Frequency
Once daily
Estimated price
$270 - $850
Website
amtrak.com
Coach Seat
$270 - $400
Flexi Coach Seat
$480 - $700
Business Coach Seat
$550 - $850
Room
$1,000 - $1,400
Train from Chicago Union Station to Buffalo Depew Station
Ave. Duration
10 h 16 min
Frequency
Twice daily
Estimated price
$75 - $220
Website
amtrak.com
Coach Seat
$75 - $120
Flexi Coach Seat
$140 - $200
Business Coach Seat
$150 - $220
Room
$330 - $460
Train from Yuma Amtrak to Chicago Union Station
Ave. Duration
2 days 9 h
Frequency
3 times a week
Estimated price
$300 - $900
Website
amtrak.com
Coach Seat
$300 - $450
Flexi Coach Seat
$500 - $800
Business Coach Seat
$650 - $900
Room
$1,100 - $1,600
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Rochester to Buffalo
Ave. Duration
1 h 22 min
Frequency
Once daily
Estimated price
$40 - $85
Website
viarail.ca
Escape
$19 - $40
Economy
$40 - $55
EconomyPlus
$55 - $85
Business
$55 - $80
Bus operators
Greyhound Canada
Phone
+1 1-800-661-8747
Email
Canada.info@greyhound.ca
Website
greyhound.ca
Bus from Toronto, ON to Buffalo, NY
Ave. Duration
1 h 37 min
Frequency
Once daily
Estimated price
$14 - $40
Website
Greyhound.ca
Advanced Purchase
$14 - $21
Online Fare
$16 - $35
Standard Fare
$25 - $40
Refundable
$29 - $45
Bus from Chicago, IL to Hamilton, ON
Ave. Duration
11 h 39 min
Frequency
Once daily
Estimated price
$40 - $110
Website
Greyhound.ca
Advanced Purchase
$40 - $65
Online Fare
$55 - $85
Standard Fare
$70 - $110
Refundable
$80 - $120
Bus from Hamilton, ON to Buffalo, NY
Ave. Duration
2 h 40 min
Frequency
Once daily
Estimated price
$12 - $35
Website
Greyhound.ca
Advanced Purchase
$12 - $18
Online Fare
$13 - $27
Standard Fare
$21 - $35
Refundable
$25 - $40
Megabus Canada
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Toronto, On to Buffalo, Ny
Ave. Duration
3 h 45 min
Frequency
5 times a day
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from San Diego, Ca to Los Angeles, Ca
Ave. Duration
3 h 20 min
Frequency
Hourly
Estimated price
$18 - $45
Website
greyhound.com
Economy
$18 - $27
Flexible
$30 - $45
Bus from Los Angeles, Ca to Pittsburgh, Pa
Ave. Duration
2 days 6 h
Frequency
Once daily
Estimated price
$220 - $600
Website
greyhound.com
Economy
$220 - $380
Flexible
$440 - $600
Bus from Pittsburgh, Pa to Erie, Pa
Ave. Duration
3 h 19 min
Frequency
Twice daily
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Erie, Pa to Buffalo, Ny
Ave. Duration
1 h 50 min
Frequency
3 times a day
Estimated price
$15 - $35
Website
greyhound.com
Economy
$15 - $23
Flexible
$27 - $35
Greyhound Mexico
Phone
01-800 890 6821
Website
greyhound.com.mx
Bus from San Diego to Yuma
Ave. Duration
3 h 40 min
Frequency
Every 4 hours
Estimated price
$45 - $65
Schedules at
greyhound.com.mx

Want to know more about travelling around United States

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More Questions & Answers

There is no direct flight from San Diego Airport to Buffalo Airport. The quickest flight takes 6 h 5 min and has one stopover.

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San Diego to Buffalo bus services, operated by Greyhound USA, arrive at Buffalo, Ny station.

More details

Buffalo is 3 h ahead of San Diego. It is currently 7:32 PM in San Diego and 10:32 PM in Buffalo.

San Diego to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.

More details

Yes, the driving distance between San Diego to Buffalo is 2605 miles. It takes approximately 41 h 20 min to drive from San Diego to Buffalo.

Get driving directions

American Airlines, Delta, United Airlines and Southwest Airlines offer flights from San Diego Airport to Buffalo Airport.

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Book your San Diego to Buffalo train tickets online with Rome2rio.

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Book your San Diego to Buffalo bus tickets online with Greyhound, Greyhound and two other operators.

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There are 141+ hotels available in Buffalo. Prices start at $62 USD per night.

More details

The best way to get from San Diego to San Diego Airport is to line 992 bus which takes 9 min and costs $2 - $3.

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