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How to get fromMexicali to Chicagoby bus, plane, bus (Greyhound, Flixbus), train or car

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There are 9 ways to get from Mexicali to Chicago by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to San Diego International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Mexicali to Tijuanabus bus
    2. Fly from San Diego International Airport (SAN) to Chicago Midway International Airport (MDW)plane plane SAN - MDW
    9h 7m
    $213–907

  2. Bus to Yuma International Airport, fly to Chicago O'Hare International Airport

    cheapest
    1. Take the bus from Mexicali to San Luis Río Coloradobus bus
    2. Fly from Yuma International Airport (YUM) to Chicago O'Hare International Airport (ORD)plane plane YUM - ORD
    11h 50m
    $104–522

  3. Bus

    1. Take the bus from Calexico Bus Station to Phoenix Bus Stationbus bus
    2. Take the bus from Phoenix Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    44h 23m
    $216–536

  4. Bus, train via San Bernardino

    1. Take the bus from Calexico Bus Station to San Bernardino Downtown Transit Centerbus bus FlixBus 2055
    2. Take the train from San Bernardino to Chicago Union Stationtrain train Southwest Chief
    2d
    $294–1,796

  5. Drive 1,925.8 mi

    1. Drive from Mexicali to Chicagocar car 1,925.8 mi
    34h 22m
    $352–508

  6. Bus to San Diego International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mexicali to Tijuanabus bus
    2. Fly from San Diego International Airport (SAN) to Chicago O'Hare International Airport (ORD)plane plane SAN - ORD
    9h 27m
    $153–657

  7. Fly Imperial County Airport to Chicago Midway International Airport

    1. Fly from Imperial County Airport (IPL) to Chicago Midway International Airport (MDW)plane plane IPL - MDW
    8h 25m
    $116–510

  8. Bus to Phoenix, fly to Chicago Midway International Airport

    1. Take the bus from Calexico Bus Station to Phoenix Bus Stationbus bus
    2. Fly from Phoenix (PHX) to Chicago Midway International Airport (MDW)plane plane PHX - MDW
    10h 48m
    $163–736

  9. Bus, train

    1. Take the bus from Mexicali to San Luis Río Coloradobus bus
    2. Take the bus from William Brook Ave @ B Street to Gila Street @ 3rd Streetbus bus 95
    3. Take the train from Yuma Amtrak to Chicago Union Stationtrain train
    2d 12h
    $206–725

Mexicali to Chicago by bus, foot, and train

Calendar3Weekly Services
Duration2d 12hAverage Duration
Ticket$206Cheapest Price
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Questions & Answers

What companies run services between Mexicali, Mexico and Chicago, IL, USA?

You can take a bus from Central de Autobuses de Mexicali to Chicago Bus Station via C. José Azueta y Blvr. López Mateos, Calexico Bus Station, Phoenix Bus Station, and St Louis Bus Station in around 44h 23m. Alternatively, Southern Airways Express and Southwest Airlines fly from Imperial County Airport (IPL) to Chicago Midway International Airport (MDW) twice daily.

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