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How to get fromMexicali to Chicagoby bus, plane, bus (Flixbus, Greyhound), train, or car

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There are 10 ways to get from Mexicali to Chicago by bus, plane, bus (Flixbus, Greyhound), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to San Diego International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Mexicali to Tijuanabus bus
    2. Fly from San Diego International Airport (SAN) to Chicago Midway International Airport (MDW)plane plane SAN - MDW
    9h 10m
    $196–810

  2. Fly Imperial County Airport to Chicago Midway International Airport

    cheapest
    1. Fly from Imperial County Airport (IPL) to Chicago Midway International Airport (MDW)plane plane IPL - MDW
    8h 20m
    $116–500

  3. Bus

    1. Take the bus from Calexico Bus Station to Indio Bus Stationbus bus
    2. Take the bus from Indio Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    47h 58m
    $344–698

  4. Bus, train via Anaheim

    1. Take the bus from Mexicali to Tijuanabus bus
    2. Take the train from San Diego to Fullerton Amtrak Stationtrain train
    3. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train
    2d 2h
    $651–1,515

  5. Drive 1,925.8 mi

    1. Drive from Mexicali to Chicagocar car 1,925.8 mi
    34h 22m
    $352–508

  6. Bus to San Diego International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mexicali to Tijuanabus bus
    2. Fly from San Diego International Airport (SAN) to Chicago O'Hare International Airport (ORD)plane plane SAN - ORD
    9h 29m
    $156–660

  7. Bus to Yuma International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Mexicali to San Luis Río Coloradobus bus
    2. Fly from Yuma International Airport (YUM) to Chicago O'Hare International Airport (ORD)plane plane YUM - ORD
    11h 57m
    $129–635

  8. Bus to Phoenix, fly to Chicago Midway International Airport

    1. Take the bus from Calexico Bus Station to Phoenix Bus Stationbus bus
    2. Fly from Phoenix (PHX) to Chicago Midway International Airport (MDW)plane plane PHX - MDW
    10h 37m
    $163–736

  9. Bus to Phoenix, fly to Chicago O'Hare International Airport

    1. Take the bus from Calexico Bus Station to Phoenix Bus Stationbus bus
    2. Fly from Phoenix (PHX) to Chicago O'Hare International Airport (ORD)plane plane PHX - ORD
    11h 5m
    $283–736

  10. Bus, train

    1. Take the bus from Mexicali to San Luis Río Coloradobus bus
    2. Take the bus from William Brook Ave @ B Street to Gila Street @ 3rd Streetbus bus 95
    3. Take the train from Yuma Amtrak to Chicago Union Stationtrain train
    2d 13h
    $706–1,678

Mexicali to Chicago by bus, foot, and train

Calendar3Weekly Services
Duration2d 13hAverage Duration
Ticket$706Cheapest Price
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Questions & Answers

What companies run services between Mexicali, Mexico and Chicago, IL, USA?

You can take a bus from Central de Autobuses de Mexicali to Chicago Bus Station via C. José Azueta y Blvr. López Mateos, Calexico Bus Station, Indio Bus Station, and St Louis Bus Station in around 47h 58m. Alternatively, Southern Airways Express and Southwest Airlines fly from Imperial County Airport (IPL) to Chicago Midway International Airport (MDW) twice daily.

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