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How to get fromCharlotte to Chicagoby plane, bus, train, car, bus (Greyhound, Flixbus) or bus (Greyhound)

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There are 8 ways to get from Charlotte to Chicago by plane, bus, train, car, bus (Greyhound, Flixbus), or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlotte Douglas International Airport to Chicago O'Hare International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    4h 23m
    $84–357

  2. Fly Charlotte Douglas International Airport to Chicago Midway International Airport

    cheapest
    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    4h 8m
    $69–387

  3. Bus, train

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the train from Toledo to Chicago Union Stationtrain train Floridian / ...
    18h 48m
    $99–265

  4. Drive 742.5 mi

    1. Drive from Charlotte to Chicagocar car 742.5 mi
    12h 51m
    $136–196

  5. Bus to Greenville–Spartanburg International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Charlotte, NC to Greenville, SCbus bus
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Chicago O'Hare International Airport (ORD)plane plane GSP - ORD
    5h 38m
    $327–498

  6. Fly Charlotte Douglas International Airport to South Bend, train

    1. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    6h 27m
    $85–447

  7. Bus via Columbus

    1. Take the bus from Charlotte Bus Station to Columbusbus bus Greyhound US0140
    2. Take the bus from Columbus to Chicago Bus Stationbus bus FlixBus N2640 / ...
    18h 59m
    $93–265

  8. Bus

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the bus from Toledo Bus Stop to Chicago Bus Stationbus bus Greyhound US0164
    20h 5m
    $87–200

Charlotte to Chicago by bus and train

Calendar7Weekly Services
Duration18h 48mAverage Duration
Ticket$99Cheapest Price
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Questions & Answers

What companies run services between Charlotte, NC, USA and Chicago, IL, USA?

American Airlines, Frontier Airlines, and United Airlines fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD) hourly. Alternatively, you can take a bus from Charlotte Bus Station to Chicago Bus Station via Columbus, S Grant Ave & E Mound St, S High St & E Rich St, and Columbus in around 18h 59m.

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