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How to get fromCharlotte to Chicagoby plane, bus (Greyhound, Amtrak), train (Amtrak), car, train, or bus

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There are 9 ways to get from Charlotte to Chicago by plane, bus (Greyhound, Amtrak), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Charlotte Douglas International Airport to Chicago Midway International Airport

    best
    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW)plane plane CLT - MDW
    4h 3m
    $74–427

  2. Bus

    1. Take the bus from Charlotte Bus Station to Toledo Bus Stopbus bus Greyhound US0140
    2. Take the bus from Toledo to Chicago Union Stationbus bus Amtrak Thruway Connecting Service
    18h 47m
    $175–322

  3. Train (Amtrak)

    1. Take the train from Charlotte Amtrak Station to Carytrain train Piedmont / ...
    2. Take the train from Cary to Chicago Union Stationtrain train Floridian
    29h 13m
    $347–800

  4. Drive 742.5 mi

    1. Drive from Charlotte to Chicagocar car 742.5 mi
    12h 52m
    $136–196

  5. Fly Charlotte Douglas International Airport to Chicago O'Hare International Airport

    1. Fly from Charlotte Douglas International Airport (CLT) to Chicago O'Hare International Airport (ORD)plane plane CLT - ORD
    4h 29m
    $94–357

  6. Fly Charlotte Douglas International Airport to South Bend, train

    1. Fly from Charlotte Douglas International Airport (CLT) to South Bend (SBN)plane plane CLT - SBN
    2. Take the train from South Bend Airport to Van Buren St.train train
    6h 26m
    $105–567

  7. Train to Piedmont Triad International Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Charlotte Amtrak Station to High Pointtrain train
    2. Fly from Piedmont Triad International Airport (GSO) to Chicago O'Hare International Airport (ORD)plane plane GSO - ORD
    6h 28m
    $110–457

  8. Fly Charlotte Douglas International Airport to General Mitchell International Airport, train

    1. Fly from Charlotte Douglas International Airport (CLT) to General Mitchell International Airport (MKE)plane plane CLT - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    6h 36m
    $168–871

  9. Bus via Hurricane

    1. Take the bus from Charlotte Bus Station to Hurricanebus bus
    2. Take the bus from Hurricane to Columbus - Mound Stbus bus
    3. Take the bus from Columbus - Mound St to Chicagobus bus
    20h 10m
    $76–209

Charlotte to Chicago by bus

Calendar2Weekly Buses
Duration18h 47mAverage Duration
Ticket$175Cheapest Price
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Questions & Answers

What companies run services between Charlotte, NC, USA and Chicago, IL, USA?

Southwest Airlines flies from Charlotte Douglas International Airport (CLT) to Chicago Midway International Airport (MDW) 3 times a day. Alternatively, you can take a bus from Charlotte Bus Station to Chicago Union Station via Toledo in around 18h 47m.

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