There are 7 ways to get from Lowell to Lexington by plane, car, bus (Greyhound, Flixbus), train, bus, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louisville International Airport, drive
best- Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane BOS - SDF
- Drive from Louisville-Airport-SDF to Lexingtoncar
6h 34m$186–508Fly to Blue Grass Airport
cheapest- Fly from Boston Logan Airport (BOS) to Blue Grass Airport (LEX)plane BOS - LEX
9h 29m$89–419Bus via Boston
- Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus
- Take the bus from Boston to Newark Penn Stationbus
- Take the bus from Newark Penn Station to Dayton Trotwood Bus Stationbus
- Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus
26h 47m$167–324Train, bus via Toledo
- Take the train from Lowell to North Stationtrain
- Take the train from Boston to Toledotrain
- Take the bus from Toledo Bus Stop to Lexington Bus Stopbus
27h 30m$149–375Drive 903 mi
- Drive from Lowell to Lexingtoncar 903 mi
16h 6m$165–238Bus
- Take the bus from Methuen - Lawrence, MA to Port Authority Bus Terminalbus
- Take the bus from Port Authority Bus Terminal to Dayton Trotwood Bus Stationbus
- Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus
29h 35m$131–317Train, bus
- Take the train from Lowell to North Stationtrain
- Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Lexington Bus Stopbus
34h 11m$224–1,575
Boston Logan Airport (BOS) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from Lowell to Lexington is to bus which costs $130 - $320 and takes 29h 35m.
The fastest way to get from Lowell to Lexington is to fly and drive which takes 6h 34m and costs $180 - $550.
The distance between Lowell and Lexington is 941 miles. The road distance is 908.3 miles.
The best way to get from Lowell to Lexington without a car is to bus via Boston which takes 26h 47m and costs $160 - $330.
It takes approximately 6h 34m to get from Lowell to Lexington, including transfers.
The best way to get from Lowell to Lexington is to bus via Boston which takes 26h 47m and costs $160 - $330. Alternatively, you can fly, which costs $85 - $420 and takes 9h 29m.
Yes, the driving distance between Lowell to Lexington is 908 miles. It takes approximately 16h 6m to drive from Lowell to Lexington.
There are 139+ hotels available in Lexington.
What companies run services between Lowell, MA, USA and Lexington, KY, USA?
You can take a bus from Robert B Kennedy Bus Transfer Center to Lexington via Boston, Newark Penn Station, Dayton Trotwood Bus Station, and Lexington Bus Stop in around 26h 47m. Alternatively, Delta, American Airlines, and United Airlines fly from Boston Logan Airport (BOS) to Blue Grass Airport (LEX) hourly.
- Website
- aa.com
Flights from Boston Logan Airport to Louisville International Airport
- Ave. Duration
- 3h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Boston Logan Airport to Louisville International Airport via Reagan Washington
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Boston Logan Airport to Blue Grass Airport via Philadelphia
- Ave. Duration
- 4h 59m
- When
- Every day
- Estimated price
- $75–400
Flights from Boston Logan Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $90–440
Flights from Boston Logan Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 45m
- When
- Friday and Saturday
- Estimated price
- $100–480
- Website
- delta.com
Flights from Boston Logan Airport to Louisville International Airport
- Ave. Duration
- 2h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Boston Logan Airport to Louisville International Airport via Detroit
- Ave. Duration
- 4h 37m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Boston Logan Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $85–430
Flights from Boston Logan Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $100–490
Flights from Boston Logan Airport to Blue Grass Airport via Reagan Washington
- Ave. Duration
- 5h 16m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–410
Flights from Boston Logan Airport to Blue Grass Airport via New York La Guardia
- Ave. Duration
- 5h 22m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–400
- Website
- united.com
Flights from Boston Logan Airport to Louisville International Airport via Washington Dulles
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $110–600
Flights from Boston Logan Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 58m
- When
- Every day
- Estimated price
- $100–480
- Website
- southwest.com
Flights from Boston Logan Airport to Louisville International Airport via Baltimore
- Ave. Duration
- 4h 50m
- When
- Monday to Saturday
- Estimated price
- $110–600
- Phone
- +1-617-222-3200
- Website
- mbta.com
Train from Lowell to North Station
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- https://www.mbta.com
- Adult
- $4–11
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Toledo
- Ave. Duration
- 17h 16m
- Frequency
- Once daily
- Estimated price
- $70–240
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $70–190
- Coach Seat short notice purchase
- $100–240
- Business - advance purchase
- $130–550
- Business Class
- $220–550
Train from Ny Moynihan Train Hall At Penn Station to Indianapolis
- Ave. Duration
- 22h 35m
- Frequency
- 3 times a week
- Estimated price
- $130–700
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 57m
- Frequency
- Every 3 hours
- Estimated price
- $30–300
- Website
- https://www.amtrak.com/home
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Coach
- $30–300
- Business Class
- $95–360
Rome2Rio's guide to Amtrak Acela
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 3h 36m
- Frequency
- Every 4 hours
- Estimated price
- $50–750
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $50–490
- First Class
- $200–750
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Robert B Kennedy Bus Transfer Center to Boston
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $10–12
- Website
- https://www.greyhound.com/
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 4 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to Dayton Trotwood Bus Station
- Ave. Duration
- 14h 30m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- https://www.greyhound.com/
Bus from Dayton Trotwood Bus Station to Lexington Bus Stop
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Toledo Bus Stop to Lexington Bus Stop
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Port Authority Bus Terminal to Dayton Trotwood Bus Station
- Ave. Duration
- 15h 10m
- Frequency
- Twice daily
- Estimated price
- $65–150
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Lexington Bus Stop
- Ave. Duration
- 3h 50m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from Methuen - Lawrence, MA to Port Authority Bus Terminal
- Ave. Duration
- 5h 25m
- Frequency
- Twice daily
- Estimated price
- $20–80
- Website
- https://www.ourbus.com
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