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How to get fromLowell to St. Louisby plane, bus (Greyhound, Flixbus), train (Amtrak), car, train or bus

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There are 6 ways to get from Lowell to St. Louis by plane, bus (Greyhound, Flixbus), train (Amtrak), car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Boston Logan Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    6h 12m
    $255–620

  2. Train, train to Theodore Francis Green State Airport, fly

    cheapest
    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Providencetrain train
    3. Fly from Theodore Francis Green State Airport (PVD) to Lambert–St. Louis International Airport (STL)plane plane PVD - STL
    9h 35m
    $137–1,218

  3. Bus

    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    29h 45m
    $145–407

  4. Train

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    29h 58m
    $182–983

  5. Drive 1,152.5 mi

    1. Drive from Lowell to St. Louiscar car 1,152.5 mi
    20h 23m
    $211–304

  6. Train, bus to Manchester Airport, fly

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Lambert–St. Louis International Airport (STL)plane plane MHT - STL
    10h 25m
    $213–995

Lowell to St. Louis by bus

Calendar5Weekly Buses
Duration29h 45mAverage Duration
Ticket$145Cheapest Price
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Questions & Answers

What companies run services between Lowell, MA, USA and St. Louis, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Robert B Kennedy Bus Transfer Center to St Louis Bus Station via Boston and Newark Penn Station in around 29h 45m.

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