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How to get fromLowell to St. LouisBy plane, train (Amtrak), train, bus, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Lowell to St. Louis by plane, train (Amtrak), train, bus, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Boston Logan Airport

    best
    1. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    5h 52m
    $244–570

  2. Bus

    cheapest
    1. Take the bus from Robert B Kennedy Bus Transfer Center to Bostonbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus
    30h 35m
    $194–388

  3. Train

    1. Take the train from Lowell to North Stationtrain train
    2. Take the train from Boston to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to St. Louistrain train
    29h 57m
    $353–783

  4. Train, bus

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from Port Authority Bus Terminal to St Louis Bus Stationbus bus
    30h 24m
    $195–383

  5. Drive 1,152.5 mi

    1. Drive from Lowell to St. Louiscar car 1,152.5 mi
    20h 28m
    $211–304

  6. Train, bus to Manchester Airport, fly

    1. Take the train from Lowell to North Stationtrain train
    2. Take the bus from Boston to Boston Manchester Airportbus bus
    3. Fly from Manchester Airport (MHT) to Lambert–St. Louis International Airport (STL)plane plane MHT - STL
    9h 29m
    $219–1,032

Lowell to St. Louis by train and subway

Calendar7Weekly Services
Duration29h 57mAverage Duration
Ticket$353Cheapest Price
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Questions & Answers

What companies run services between Lowell, MA, USA and St. Louis, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a train from Lowell to St. Louis via North Station, North Station, Back Bay, Boston, and Chicago Union Station in around 29h 57m.

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