There are 10 ways to get from Chicago to Lexington by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus via Cincinnati  •  9h

  1. Take the bus from Chicago to University of Cincinnati
  2. Take the bus from Cincinnati, Oh to Lexington, Ky 1109 / ...

$66 - $101

9 alternative options

Train, bus  •  10h 29m

  1. Take the train from Chicago Union Station to Lafayette Amtrak Station
  2. Take the bus from Lafayette to Cincinnati, Oh
  3. Take the bus from Cincinnati, Oh to Lexington, Ky

$96 - $132

Bus  •  10h 58m

  1. Take the bus from Chicago Union Station to Louisville, KY
  2. Take the bus from Louisville, KY to Lexington, KY Evansville / ...

$88 - $118

Drive  •  6h 17m

  1. Drive from Chicago to Lexington 376.7 miles

$35 - $55

Fly Chicago O'Hare to Lexington, line 3 bus  •  5h 27m

  1. Fly from Chicago O'Hare (ORD) to Lexington (LEX) ORD - LEX
  2. Take the line 3 bus from Transit Center to Appian Way @ Tates Creek Outbound

Fly Chicago Midway to Lexington  •  7h 55m

  1. Fly from Chicago Midway (MDW) to Lexington (LEX) MDW - LEX

$252 - $605

Fly Chicago O'Hare to Covington, bus  •  7h 2m

  1. Fly from Chicago O'Hare (ORD) to Covington (CVG) ORD - CVG
  2. Take the bus from Cincinnati, Oh to Lexington, Ky

$92 - $154

Fly Chicago Midway to Covington, bus  •  6h 47m

  1. Fly from Chicago Midway (MDW) to Covington (CVG) MDW - CVG
  2. Take the bus from Cincinnati, Oh to Lexington, Ky

$142 - $2,664

Fly Chicago Midway to Louisville, line 28 bus, bus  •  7h 22m

  1. Fly from Chicago Midway (MDW) to Louisville (SDF) MDW - SDF
  2. Take the line 28 bus from UPS Worldport to W Jefferson @ S 6th
  3. Take the bus from Louisville, KY to Lexington, KY

$142 - $690

Fly Chicago O'Hare to Louisville, line 28 bus, bus  •  7h 45m

  1. Fly from Chicago O'Hare (ORD) to Louisville (SDF) ORD - SDF
  2. Take the line 28 bus from UPS Worldport to W Jefferson @ S 6th
  3. Take the bus from Louisville, KY to Lexington, KY

$146 - $340

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Questions & Answers

The cheapest way to get from Chicago to Lexington is to drive which costs $35 - $55 and takes 6h 17m.

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The quickest way to get from Chicago to Lexington is to drive which costs $35 - $55 and takes 6h 17m.

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The distance between Chicago and Lexington is 318 miles. The road distance is 376.7 miles.

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The best way to get from Chicago to Lexington without a car is to bus via Cincinnati which takes 9h and costs $65 - $110.

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It takes approximately 9h to get from Chicago to Lexington, including transfers.

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The best way to get from Chicago to Lexington is to bus via Cincinnati which takes 9h and costs $65 - $110. Alternatively, you can fly, which costs $250 - $650 and takes 7h 55m.

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The quickest flight from Chicago O'Hare Airport to Lexington Airport is the direct flight which takes 1h 13m.

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Lexington is 1h ahead of Chicago. It is currently 4:40 PM in Chicago and 5:40 PM in Lexington.

Yes, the driving distance between Chicago to Lexington is 377 miles. It takes approximately 6h 17m to drive from Chicago to Lexington.

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American Airlines and United Airlines offer flights from Chicago O'Hare Airport to Lexington Airport.

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Map of how to get from Chicago to Lexington.
Launch map view
  • Distance: 318 miles
  • Duration: 9h

What companies run services between Chicago, IL, USA and Lexington, KY, USA?

You can take a bus from Chicago to Lexington via University of Cincinnati, Jefferson Ave & University Ave, Government Square Area D, Cincinnati, Oh, and Lexington, Ky in around 9h. Alternatively, Delta, Southwest Airlines and American Airlines fly from Chicago to Lexington hourly.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to Covington
Ave. Duration
1h 8m
When
Every day
Estimated price
$110 - $480
Flights from Chicago Midway to Louisville
Ave. Duration
1h 10m
When
Every day
Estimated price
$75 - $300
United Airlines
Website
united.com
Flights from Chicago O'Hare to Lexington
Ave. Duration
1h 20m
When
Every day
Estimated price
$110 - $450
Flights from Chicago O'Hare to Covington
Ave. Duration
1h 23m
When
Every day
Estimated price
$80 - $170
Flights from Chicago O'Hare to Louisville
Ave. Duration
1h 23m
When
Every day
Estimated price
$140 - $280
American Airlines
Website
aa.com
Flights from Chicago O'Hare to Lexington
Ave. Duration
1h 18m
When
Every day
Estimated price
$65 - $370
Flights from Chicago O'Hare to Covington
Ave. Duration
1h 10m
When
Every day
Estimated price
$45 - $100
Flights from Chicago O'Hare to Louisville
Ave. Duration
1h 21m
When
Every day
Estimated price
$95 - $430
Delta
Website
delta.com
Flights from Chicago Midway to Lexington via Detroit
Ave. Duration
4h 33m
When
Every day
Estimated price
$250 - $600
Flights from Chicago Midway to Lexington via Atlanta
Ave. Duration
4h 23m
When
Every day
Estimated price
$350 - $1,100
Flights from Chicago Midway to Lexington via Minneapolis
Ave. Duration
4h 40m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$380 - $1,200
Flights from Chicago O'Hare to Covington
Ave. Duration
1h 14m
When
Every day
Estimated price
$65 - $120
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Chicago Union Station to Lafayette Amtrak Station
Ave. Duration
2h 57m
Frequency
3 times a week
Estimated price
$30 - $45
Website
amtrak.com
Coach Seat
$30 - $45
Premium
$190 - $270
Flexi Coach Seat
$45 - $70
Business Seat
$45 - $65
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Chicago to University of Cincinnati
Ave. Duration
5h 40m
Frequency
Twice daily
Estimated price
$22 - $45
Book at
megabus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Cincinnati, Oh to Lexington, Ky
Ave. Duration
1h 25m
Frequency
4 times a day
Estimated price
$15 - $22
Website
greyhound.com
Economy
$15 - $22
Flexible
$30 - $50
Bus from Lafayette to Cincinnati, Oh
Ave. Duration
3h 55m
Frequency
Once daily
Estimated price
$24 - $35
Website
greyhound.com
Economy
$24 - $35
Flexible
$45 - $65
Amtrak Thruway

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak Thruway
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Bus from Chicago Union Station to Louisville, KY
Ave. Duration
7h 20m
Frequency
4 times a day
Estimated price
$50 - $75
Website
amtrak.com
Lextran
Website
lextran.com
Bus from Transit Center to Appian Way @ Tates Creek Outbound
Ave. Duration
31 min
Frequency
Hourly
Schedules at
mystop.lextran.com
Transit Authority of River City

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More Questions & Answers

There are 94+ hotels available in Lexington. Prices start at $100 USD per night.

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The best way to get from Chicago to Chicago O'Hare Airport is to subway which takes 43 min and costs $2 - $5.

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