There are 10 ways to get from Isernia to Milan by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Isernia to Roma TerminiRe
- Take the train from Roma Termini to Milano CentraleFr / ...
5h 44m€84–178Bus
cheapest- Take the bus from Isernia to Termoli Terminal BusCb 014
- Take the bus from Termoli Autostazione to Milano, San Donato M3Vieste
10h 20m€41–88Drive 711.7 km
- Drive from Isernia to Milan711.7 km
7h 4m€110–159Train to Naples Airport, fly to Milan Linate Airport
- Take the train from Isernia to Napoli Centrale
- Fly from Naples Airport (NAP) to Milan Linate Airport (LIN)NAP - LIN
4h 53m€60–190Train via Milan Rogoredo
- Take the train from Isernia to Roma TerminiRe
- Take the train from Roma Termini to Milan Rogoredo9984 / ...
6h 17m€84–178Train via Milan Rogoredo #2
- Take the train from Isernia to Roma TiburtinaRe
- Take the train from Roma Tiburtina to Milan Rogoredo9970 / ...
6h 18m€57–137Bus via Florence
- Take the bus from Isernia to Florence Villa Constanza Bus Station433
- Take the bus from Florence Villa Constanza Bus Station to Milano, San Donato M3N528 / ...
14h 20m€44–113Train to Fiumicino International Airport, fly to Milan Linate Airport
- Take the train from Isernia to Roma Termini
- Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)FCO - LIN
5h 31m€88–237Train to Naples Airport, fly to Il Caravaggio International Airport
- Take the train from Isernia to Napoli Centrale
- Fly from Naples Airport (NAP) to Il Caravaggio International Airport (BGY)NAP - BGY
5h 31m€64–232Train to Naples Airport, fly to Milano Malpensa Airport, train
- Take the train from Isernia to Napoli Centrale
- Fly from Naples Airport (NAP) to Milano Malpensa Airport (MXP)NAP - MXP
- Take the train from Malpensa Aeroporto T1 to Milano Porta Garibaldi
5h 51m€47–182
Isernia to Milan by train
Questions & Answers
The cheapest way to get from Isernia to Milan is to bus via Florence which costs €40 - €120 and takes 14h 20m.
The fastest way to get from Isernia to Milan is to train and fly which takes 4h 53m and costs €55 - €190.
No, there is no direct bus from Isernia to Milan. However, there are services departing from Isernia and arriving at Milano, San Donato M3 via Termoli Autostazione. The journey, including transfers, takes approximately 10h 20m.
No, there is no direct train from Isernia to Milan. However, there are services departing from Isernia and arriving at Milano Centrale via Roma Termini. The journey, including transfers, takes approximately 5h 44m.
The distance between Isernia and Milan is 749 km. The road distance is 711.7 km.
The best way to get from Isernia to Milan without a car is to train which takes 5h 44m and costs €80 - €180.
It takes approximately 5h 44m to get from Isernia to Milan, including transfers.
Isernia to Milan bus services, operated by FlixBus, depart from Isernia station.
Isernia to Milan train services, operated by Trenitalia S.p.A., depart from Isernia station.
The best way to get from Isernia to Milan is to train which takes 5h 44m and costs €80 - €180. Alternatively, you can bus, which costs €40 - €90 and takes 10h 20m.
What companies run services between Isernia, Italy and Milan, Italy?
You can take a train from Isernia to Milano Centrale via Roma Termini in around 5h 44m. Alternatively, you can take a bus from Isernia to Milano, San Donato M3 via Termoli Autostazione in around 10h 20m.
- Website
- ita-airways.com
Flights from Naples Airport to Milan Linate Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- €40–170
Flights from Naples Airport to Milan Linate Airport via Fiumicino International Airport
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- €40–170
Flights from Fiumicino International Airport to Milan Linate Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €45–150
Flights from Fiumicino International Airport to Milan Linate Airport via Naples Airport
- Ave. Duration
- 3h 5m
- When
- Every day
- Estimated price
- €45–150
- Website
- ryanair.com
Flights from Naples Airport to Il Caravaggio International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- €45–170
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €40–150
- Website
- easyjet.com
Flights from Naples Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- €26–140
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a day
- Estimated price
- €35–60
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Napoli Centrale
- Ave. Duration
- 2h 5m
- Frequency
- 4 times a day
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Roma Tiburtina
- Ave. Duration
- 2h 26m
- Frequency
- 6 times a week
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 8m
- Frequency
- Every 30 minutes
- Estimated price
- €45–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Milano Centrale
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
Train from Roma Termini to Milan Rogoredo
- Ave. Duration
- 2h 52m
- Frequency
- Every 3 hours
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
Train from Roma Tiburtina to Milan Rogoredo
- Ave. Duration
- 2h 52m
- Frequency
- Every 3 hours
- Estimated price
- €45–120
- Website
- https://www.italotreno.it/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Malpensa Aeroporto T1 to Milano Porta Garibaldi
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 02-72494949
- Website
- malpensaexpress.it
Train from Malpensa Aeroporto T1 to Milano Porta Garibaldi
- Ave. Duration
- 42 min
- Frequency
- Hourly
- Estimated price
- €15
- Website
- https://www.malpensaexpress.it/en/
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Isernia to Termoli Terminal Bus
- Ave. Duration
- 1h 35m
- Frequency
- Once a week
- Estimated price
- €5–8
- Schedules at
- atm-molise.it
- Phone
- +39 (0) 0882 - 228960
- Website
- ferroviedelgargano.com
Bus from Termoli Autostazione to Milano, San Donato M3
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Estimated price
- €55–80
- Schedules at
- ferroviedelgargano.com
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Termoli Autostazione to Milano, San Donato M3
- Ave. Duration
- 9h 5m
- Frequency
- Once daily
- Estimated price
- €35–80
- Website
- https://www.flixbus.co.uk
Bus from Isernia to Florence Villa Constanza Bus Station
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- €30–80
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Milano, San Donato M3
- Ave. Duration
- 3h 25m
- Frequency
- Every 3 hours
- Estimated price
- €12–35
- Website
- https://www.flixbus.co.uk
Want to know more about travelling around Italy
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More Questions & Answers
Isernia to Milan bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Isernia to Milan train services, operated by Trenitalia S.p.A., arrive at Roma Termini station.
Yes, the driving distance between Isernia to Milan is 712 km. It takes approximately 7h 4m to drive from Isernia to Milan.
Book your Isernia to Milan train tickets online with Omio.
Book your Isernia to Milan bus tickets online with Omio and FlixBus.
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