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How to get fromIsernia to Pisaby train (Trenitalia), bus, car, train, or plane

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There are 8 ways to get from Isernia to Pisa by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Isernia to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Pisa Centraletrain train Fa / ...
    5h 33m
    €58–125

  2. Bus

    cheapest
    1. Take the bus from Isernia to Roma, Autostazione Tiburtinabus bus Campobasso / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Pisabus bus N1508 / ...
    7h 45m
    €35–67

  3. Drive  507.2 km

    1. Drive from Isernia to Pisacar car 507.2 km
    5h 4m
    €81–117

  4. Train to Naples Airport, fly to Pisa International Airport

    1. Take the train from Isernia to Casertatrain train
    2. Fly from Naples Airport (NAP) to Pisa International Airport (PSA)plane plane NAP - PSA
    6h 42m
    €73–251

  5. Train via Florence (Trenitalia)

    1. Take the train from Isernia to Roma Terminitrain train Re
    2. Take the train from Roma Termini to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train Re
    5h 49m
    €60–120

  6. Train, bus

    1. Take the train from Isernia to Cassinotrain train Re
    2. Take the bus from Cassino to Pisabus bus
    8h 7m
    €36–55

  7. Train to Fiumicino International Airport, fly to Florence Peretola Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    6h 58m
    €97–258

  8. Train to Fiumicino International Airport, fly to Bologna Guglielmo Marconi Airport, train

    1. Take the train from Isernia to Roma Terminitrain train
    2. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    3. Take the train from Bologna Centrale to Firenze S.M.N.train train
    4. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    7h 44m
    €89–261

Isernia to Pisa by train (Trenitalia)

Calendar35Weekly Trains
Duration5h 33mAverage Duration
Ticket€58Cheapest Price
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Questions & Answers

Map of how to get from Isernia to Pisa.ExpandLaunch map view
  • Distance: 521.9 km
  • Duration: 5h 33m

What companies run services between Isernia, Italy and Pisa, Italy?

You can take a train from Isernia to Pisa Centrale via Roma Termini in around 5h 33m. Alternatively, you can take a bus from Isernia to Pisa via Roma, Autostazione Tiburtina in around 7h 45m.

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Bus operators

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