There are 9 ways to get from Isernia to Pisa by train (Trenitalia), bus, car, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Trenitalia)
best- Take the train from Isernia to Roma Terminitrain Re
- Take the train from Roma Termini to Pisa Centraletrain Fa / ...
5h 32m€31–112Bus
cheapest- Take the bus from Isernia to Roma, Autostazione Tiburtinabus Campobasso / ...
- Take the bus from Roma, Autostazione Tiburtina to Pisabus N1508 / ...
7h 45m€29–53Drive 507.2 km
- Drive from Isernia to Pisacar 507.2 km
5h 4m€79–114Train to Naples Airport, fly to Pisa International Airport
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Pisa International Airport (PSA)plane NAP - PSA
6h 44m€53–234Train via Rome (Trenitalia)
- Take the train from Isernia to Roma Tiburtinatrain Re
- Take the train from Roma Tiburtina to Pisa Centraletrain Fa
5h 39m€57–112Train, bus
- Take the train from Isernia to Cassinotrain Re
- Take the bus from Cassino to Pisabus
8h 1m€35–52Train to Fiumicino International Airport, fly to Florence Peretola Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane FCO - FLR
- Take the train from Firenze S.M.N. to Pisa Centraletrain
7h 6m€78–214Train to Fiumicino International Airport, fly to Bologna Guglielmo Marconi Airport, train
- Take the train from Isernia to Roma Terminitrain
- Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane FCO - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.train
- Take the train from Firenze S.M.N. to Pisa Centraletrain
7h 57m€67–252Train to Naples Airport, fly to Genoa Cristoforo Colombo Airport, train
- Take the train from Isernia to Casertatrain
- Fly from Naples Airport (NAP) to Genoa Cristoforo Colombo Airport (GOA)plane NAP - GOA
- Take the train from Genova P.Za Principe to Pisa Centraletrain
8h 27m€63–204
Isernia to Pisa by train (Trenitalia)
Questions & Answers
The cheapest way to get from Isernia to Pisa is to bus which costs €28 - €55 and takes 7h 45m.
The fastest way to get from Isernia to Pisa is to drive which takes 5h 4m and costs €75 - €120.
No, there is no direct bus from Isernia to Pisa. However, there are services departing from Isernia and arriving at Pisa via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 45m.
No, there is no direct train from Isernia to Pisa. However, there are services departing from Isernia and arriving at Pisa Centrale via Roma Termini. The journey, including transfers, takes approximately 5h 32m.
The distance between Isernia and Pisa is 522 km. The road distance is 507.2 km.
The best way to get from Isernia to Pisa without a car is to train which takes 5h 32m and costs €30 - €120.
It takes approximately 5h 32m to get from Isernia to Pisa, including transfers.
Isernia to Pisa bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., depart from Isernia station.
Isernia to Pisa train services, operated by Trenitalia, depart from Isernia station.
The best way to get from Isernia to Pisa is to train which takes 5h 32m and costs €30 - €120. Alternatively, you can bus, which costs €28 - €55 and takes 7h 45m.
What companies run services between Isernia, Italy and Pisa, Italy?
You can take a train from Isernia to Pisa Centrale via Roma Termini in around 5h 32m. Alternatively, you can take a bus from Isernia to Pisa via Roma, Autostazione Tiburtina in around 7h 45m.
- Website
- ita-airways.com
Flights from Fiumicino International Airport to Florence Peretola Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- €50–140
Flights from Fiumicino International Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 3m
- When
- Every day
- Estimated price
- €45–120
Flights from Naples Airport to Genoa Cristoforo Colombo Airport via Fiumicino International Airport
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- €60–120
- Website
- ryanair.com
Flights from Naples Airport to Pisa International Airport via Palermo
- Ave. Duration
- 3h 58m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €55–220
Flights from Naples Airport to Pisa International Airport via Catania
- Ave. Duration
- 3h 40m
- When
- Friday and Sunday
- Estimated price
- €55–220
Flights from Naples Airport to Pisa International Airport via Cagliari
- Ave. Duration
- 6h 30m
- When
- Friday
- Estimated price
- €55–220
Flights from Naples Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 20m
- When
- Friday and Sunday
- Estimated price
- €35–150
- Website
- volotea.com
Flights from Naples Airport to Genoa Cristoforo Colombo Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €27–120
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Isernia to Roma Termini
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a day
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 4h 11m
- Frequency
- Every 4 hours
- Estimated price
- €19–28
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Caserta
- Ave. Duration
- 1h 18m
- Frequency
- 4 times a day
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Roma Tiburtina
- Ave. Duration
- 2h 26m
- Frequency
- 6 times a week
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
Train from Isernia to Cassino
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Pisa Centrale
- Ave. Duration
- 1h 28m
- Frequency
- Every 30 minutes
- Estimated price
- €6–9
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 3h 32m
- Frequency
- Once a week
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 2h 22m
- Frequency
- Every 4 hours
- Estimated price
- €45–95
- Schedules at
- trenitalia.com
Train from Roma Tiburtina to Pisa Centrale
- Ave. Duration
- 2h 13m
- Frequency
- Once daily
- Estimated price
- €45–95
- Schedules at
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Hourly
- Estimated price
- €13–26
- Schedules at
- trenitalia.com
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 1h 57m
- Frequency
- Every 4 hours
- Estimated price
- €23–45
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Roma Termini to Pisa Centrale
- Ave. Duration
- 3h 16m
- Frequency
- 3 times a day
- Estimated price
- €30–75
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Genova P.Za Principe to Pisa Centrale
- Ave. Duration
- 2h 43m
- Frequency
- Every 4 hours
- Estimated price
- €16–40
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €28–40
- Website
- https://www.italotreno.it/en
- Smart Economy
- €28–40
- Smart Flex
- €29–40
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once a week
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Isernia to Roma, Autostazione Tiburtina
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €10–19
- Website
- https://www.flixbus.co.uk
Bus from Roma, Autostazione Tiburtina to Pisa
- Ave. Duration
- 4h 35m
- Frequency
- 4 times a day
- Estimated price
- €20–35
- Website
- https://www.flixbus.co.uk
- Phone
- +39 089 233 899
- salerno@autolineecurcio.it
- Website
- autolineecurcio.it
Bus from Cassino to Pisa
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- €30–45
- Website
- https://www.autolineecurcio.it/
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More Questions & Answers
Isernia to Pisa bus services, operated by ATM Azienda di Trasporti Molisana S.p.A., arrive at Roma, Autostazione Tiburtina station.
Isernia to Pisa train services, operated by Trenitalia, arrive at Roma Termini station.
Yes, the driving distance between Isernia to Pisa is 507 km. It takes approximately 5h 4m to drive from Isernia to Pisa.
Book your Isernia to Pisa train tickets online with Omio.
Book your Isernia to Pisa bus tickets online with Omio and FlixBus.
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