Rome2Rio

How to get fromHyannis to Lexingtonby plane, bus (Greyhound, Flixbus), bus, train, car or bus (Greyhound)

Find Transport to Lexington

See all options

There are 9 ways to get from Hyannis to Lexington by plane, bus (Greyhound, Flixbus), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Barnstable Municipal Airport to Blue Grass Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Blue Grass Airport (LEX)plane plane HYA - LEX
    7h 9m
    $83–415

  2. Bus via Boston

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to Newark Penn Stationbus bus
    3. Take the bus from Newark Penn Station to Dayton Trotwood Bus Stationbus bus
    4. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus
    27h 52m
    $184–347

  3. Bus, train via Toledo

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo Bus Stop to Lexington Bus Stopbus bus
    28h 20m
    $222–808

  4. Drive 936.8 mi

    1. Drive from Hyannis to Lexingtoncar car 936.8 mi
    17h 2m
    $171–247

  5. Bus to Boston Logan Airport, fly to Louisville International Airport, drive

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane plane BOS - SDF
    3. Drive from Louisville-Airport-SDF to Lexingtoncar car
    7h 34m
    $202–527

  6. Bus to Boston Logan Airport, fly to Blue Grass Airport

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Blue Grass Airport (LEX)plane plane BOS - LEX
    10h 29m
    $105–438

  7. Fly Barnstable Municipal Airport to Covington, bus

    1. Fly from Barnstable Municipal Airport (HYA) to Covington (CVG)plane plane HYA - CVG
    2. Take the bus from Cincinnati Bus Station to Lexington Bus Stopbus bus
    9h 29m
    $198–832

  8. Bus

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Dayton Trotwood Bus Stationbus bus
    4. Take the bus from Dayton Trotwood Bus Station to Lexington Bus Stopbus bus
    28h 42m
    $146–326

  9. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Lexington Bus Stopbus bus
    34h 58m
    $227–1,598

Barnstable Municipal Airport (HYA) to Blue Grass Airport (LEX) flights

Calendar14Weekly Planes
Duration5h 8mAverage Duration
Ticket$81Cheapest Price
See schedules

Questions & Answers

What companies run services between Hyannis, MA, USA and Lexington, KY, USA?

American Airlines, Delta, and United Airlines fly from Barnstable Municipal Airport (HYA) to Blue Grass Airport (LEX) twice daily. Alternatively, you can take a bus from Hyannis Transportation Center to Lexington via Boston, Bus Terminal South Station, Boston, Newark Penn Station, Dayton Trotwood Bus Station, and Lexington Bus Stop in around 27h 52m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Hyannis

Trips to Lexington

Popular routes