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How to get fromHyannis to Myrtle Beachby plane, bus, train, bus (Flixbus, Greyhound), car or bus (Greyhound)

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There are 6 ways to get from Hyannis to Myrtle Beach by plane, bus, train, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR)plane plane HYA - MYR
    5h 26m
    $108–544

  2. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Charleston Amtrak Stationtrain train
    4. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    24h 14m
    $241–1,227

  3. Bus

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York City Chinatownbus bus
    3. Take the bus from New York, NY to Camdenbus bus Nyc
    4. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    25h 40m
    $156–280

  4. Drive 885.1 mi

    1. Drive from Hyannis to Myrtle Beachcar car 885.1 mi
    16h 56m
    $162–234

  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    5h 40m
    $109–370

  6. Bus via Chesapeake

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from Port Authority Bus Terminal to Norfolkbus bus
    4. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    27h
    $175–363

Hyannis to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration24h 14mAverage Duration
Ticket$241Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Myrtle Beach, SC, USA?

American Airlines, Cape Air, and Delta fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR) twice daily. Alternatively, you can take a bus from Hyannis Transportation Center to Myrtle Beach Bus Station via Boston, Bus Terminal South Station, Boston, New York City Chinatown, New York, NY, and Camden in around 25h 40m.

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