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How to get fromHyannis to Myrtle Beachby plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

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There are 6 ways to get from Hyannis to Myrtle Beach by plane, bus (Flixbus, Greyhound), bus, train, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Barnstable Municipal Airport

    best
    1. Fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR)plane plane HYA - MYR
    4h 39m
    $103–499
  2. Bus via Chesapeake

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from Times Square – 37th St. to Norfolk, VA - Best Squarebus bus
    4. Take the bus from Norfolk to Myrtle Beach Bus Stationbus bus
    24h 59m
    $160–265
  3. Bus, train

    1. Take the bus from Hyannis Transportation Center to Boston South Busesbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Fayetteville Amtrak Stationtrain train
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    27h 56m
    $287–1,245
  4. Drive 885.4 mi

    1. Drive from Hyannis to Myrtle Beachcar car 885.4 mi
    16h 55m
    $162–234
  5. Bus to Boston Logan Airport, fly

    1. Take the bus from Hyannis Transportation Center to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Myrtle Beach (MYR)plane plane BOS - MYR
    5h 37m
    $129–390
  6. Bus

    1. Take the bus from Hyannis Transportation Center to Providence Bus Terminalbus bus
    2. Take the bus from Peter Pan Bus Terminal to Port Authority Bus Terminalbus bus
    3. Take the bus from New York, NY to Fayetteville, NCbus bus Nyc
    4. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    30h 55m
    $191–353

Hyannis to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration27h 56mAverage Duration
Ticket$287Cheapest Price
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Questions & Answers

What companies run services between Hyannis, MA, USA and Myrtle Beach, SC, USA?

American Airlines, Cape Air, and Delta fly from Barnstable Municipal Airport (HYA) to Myrtle Beach (MYR) twice daily. Alternatively, you can take a bus from Hyannis Transportation Center to Myrtle Beach Bus Station via Boston, Bus Terminal South Station, Boston, New York Midtown, Times Square – 37th St., and Norfolk in around 24h 59m.

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