Rome2Rio

How to get fromHannibal to Milwaukeeby train (Amtrak), car, shuttle, plane, train, or bus

Find Transport to Milwaukee

See all options

There are 5 ways to get from Hannibal to Milwaukee by train (Amtrak), car, shuttle, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Quincy Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    7h 20m
    $162–308

  2. Drive  368.2 mi

    cheapest
    1. Drive from Hannibal to Milwaukeecar car 368.2 mi
    6h 26m
    $68–98

  3. Shuttle, fly to General Mitchell International Airport

    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    5h 2m
    $501–876

  4. Train, bus

    1. Take the train from Quincy Amtrak Station to La Grange Amtraktrain train Carl Sandburg / ...
    2. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus Wisconsin Coach Lines
    8h 15m
    $180–293

  5. Shuttle, fly to Chicago O'Hare International Airport, bus

    1. Take a shuttle bus from Hannibal to St. Louisshuttle bus
    2. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    3. Take the bus from Chicago to Milwaukee Intermodal Stationbus bus
    7h 9m
    $352–748

Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE) flights

Calendar16Weekly Planes
Duration1h 32mAverage Duration
Ticket$81Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Hannibal to Milwaukee.ExpandLaunch map view
  • Distance: 414.6 mi
  • Duration: 7h 20m

What companies run services between Hannibal, MO, USA and Milwaukee, WI, USA?

You can take a vehicle from Hannibal to Milwaukee via Quincy Amtrak Station and Chicago Union Station in around 7h 20m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound