There are 11 ways to get from Lexington to Milwaukee by car, bus, train, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, bus, train
best- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville Bus Station to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Milwaukeetrain
12h 30m$76–163Fly Blue Grass Airport to Chicago O'Hare International Airport, bus
cheapest- Fly from Blue Grass Airport (LEX) to Chicago O'Hare International Airport (ORD)plane LEX - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
7h 12m$56–300Drive 451 mi
- Drive from Lexington to Milwaukeecar 451 mi
8h 15m$83–119Fly Blue Grass Airport to General Mitchell International Airport
- Fly from Blue Grass Airport (LEX) to General Mitchell International Airport (MKE)plane LEX - MKE
7h 37m$80–475Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
12h 32m$67–139Drive, bus via Milwaukee Mitchell Airport
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Mitchell Airportbus
13h 8m$69–136Drive, bus, train via Lafayette (Amtrak)
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Lafayette Amtrak Stationbus
- Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
14h 31m$96–193Drive to Covington, fly to Chicago O'Hare International Airport, bus
- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Chicago O'Hare International Airport (ORD)plane CVG - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
5h 34m$179–850Drive to Louisville International Airport, fly to Chicago O'Hare International Airport, bus
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Chicago O'Hare International Airport (ORD)plane SDF - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
5h 40m$78–389Drive to Louisville International Airport, fly to Chicago Midway International Airport, train
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)plane SDF - MDW
- Take the train from Chicago Union Station to Milwaukeetrain
6h 7m$96–469Drive to Covington, fly to Chicago Midway International Airport, train
- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Chicago Midway International Airport (MDW)plane CVG - MDW
- Take the train from Chicago Union Station to Milwaukeetrain
6h 1m$192–440
Blue Grass Airport (LEX) to General Mitchell International Airport (MKE) flights
Questions & Answers
The cheapest way to get from Lexington to Milwaukee is to drive and bus which costs $65 - $140 and takes 12h 32m.
The fastest way to get from Lexington to Milwaukee is to drive and fly and bus which takes 5h 34m and costs $170 - $850.
The distance between Lexington and Milwaukee is 471 miles. The road distance is 453.6 miles.
It takes approximately 12h 30m to get from Lexington to Milwaukee, including transfers.
Milwaukee is 1h behind Lexington. It is currently 10:46 AM in Lexington and 9:46 AM in Milwaukee.
Yes, the driving distance between Lexington to Milwaukee is 454 miles. It takes approximately 8h 15m to drive from Lexington to Milwaukee.
There are 311+ hotels available in Milwaukee.
What companies run services between Lexington, KY, USA and Milwaukee, WI, USA?
American Airlines, United Airlines, and Delta fly from Blue Grass Airport (LEX) to General Mitchell International Airport (MKE) hourly.
- Website
- united.com
Flights from Blue Grass Airport to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $75–470
Flights from Covington to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $50–350
Flights from Louisville International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $50–340
Flights from Blue Grass Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $40–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–50
- Website
- Amtrak
Train from Lafayette Amtrak Station to Chicago Union Station
- Ave. Duration
- 3h 24m
- Frequency
- 3 times a week
- Estimated price
- $30–70
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–50
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–50
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–50
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Louisville Bus Station to Chicago Bus Station
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Louisville Bus Station to Chicago Bus Station
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $13–26
- Website
- Greyhound
Bus from Louisville Bus Station to Chicago Bus Station
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Chicago to Milwaukee Intermodal Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- Greyhound
Bus from Chicago to Milwaukee Intermodal Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- Greyhound
Bus from Chicago to Milwaukee Intermodal Station
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $12–23
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide






