There are 8 ways to get from Hannibal to Madison by train, bus, car, taxi, plane, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Quincy Amtrak Station to Chicago Union Stationtrain Carl Sandburg / ...
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus Van Galder
9h 9m$251–393Drive 319.7 mi
cheapest- Drive from Hannibal to Madisoncar 319.7 mi
5h 57m$59–85Taxi to Quincy Regional Airport, fly to Chicago O'Hare International Airport, bus
- Take the taxi from Hannibal to Quincy Regional Airport (UIN)taxi
- Fly from Quincy Regional Airport (UIN) to Chicago O'Hare International Airport (ORD)plane UIN - ORD
- Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus
6h 21m$221–345Train, bus via Milwaukee
- Take the train from Quincy Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.bus
9h 55m$290–453Taxi to Quincy Regional Airport, fly to Dane County Regional Airport-Truax Field
- Take the taxi from Hannibal to Quincy Regional Airport (UIN)taxi
- Fly from Quincy Regional Airport (UIN) to Dane County Regional Airport-Truax Field (MSN)plane UIN - MSN
5h 8m$189–742Shuttle to Lambert–St. Louis International Airport, fly to General Mitchell International Airport, bus
- Take a shuttle bus from Hannibal to St. Louis
- Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane STL - MKE
- Take the bus from Mitchell Airport to Madison, WI-Lake St.bus
7h 30m$518–908Shuttle to Lambert–St. Louis International Airport, fly to Chicago O'Hare International Airport, bus
- Take a shuttle bus from Hannibal to St. Louis
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
- Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus
8h 47m$362–828Train to Chicago O'Hare International Airport, fly to Dane County Regional Airport-Truax Field
- Take the train from Quincy Amtrak Station to La Grange Amtraktrain
- Fly from Chicago O'Hare International Airport (ORD) to Dane County Regional Airport-Truax Field (MSN)plane ORD - MSN
8h 37m$277–708
Quincy Regional Airport (UIN) to Chicago O'Hare International Airport (ORD) flights
Comparing Your Travel Options
The cheapest way to get from Hannibal to Madison is to drive which costs $55 - $85 and takes 5h 57m.
The fastest way to get from Hannibal to Madison is to taxi and fly which takes 5h 8m and costs $180 - $750.
The distance between Hannibal and Madison is 485 miles. The road distance is 321.6 miles.
The best way to get from Hannibal to Madison without a car is to train and bus which takes 9h 9m and costs $250 - $400.
It takes approximately 9h 9m to get from Hannibal to Madison, including transfers.
Yes, the driving distance between Hannibal to Madison is 322 miles. It takes approximately 5h 57m to drive from Hannibal to Madison.
There are 140+ hotels available in Madison.
What companies run services between Hannibal, MO, USA and Madison, WI, USA?
There is no direct connection from Hannibal to Madison. However, you can take the taxi to Quincy Amtrak Station, take the train to Chicago Union Station, walk to W Jackson Blvd, after S Clinton St, then take the bus to 250 N. Lake St - Madison UW Campus. Alternatively, you can drive from Hannibal to Madison in around 5h 57m.
- Website
- united.com
Flights from Quincy Regional Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare International Airport
- Ave. Duration
- 3h 47m
- When
- Every day
- Estimated price
- $190–750
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $45–370
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Dane County Regional Airport-Truax Field
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $45–370
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 17m
- When
- Every day
- Estimated price
- $80–550
Flights from Lambert–St. Louis International Airport to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 3h 25m
- When
- Saturday
- Estimated price
- $80–550
- Website
- contouraviation.com
Flights from Quincy Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $120–150
- Website
- delta.com
Flights from Quincy Regional Airport to Dane County Regional Airport-Truax Field via Chicago O'Hare International Airport, Detroit
- Ave. Duration
- 7h 12m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $40–270
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Quincy Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 21m
- Frequency
- Twice daily
- Estimated price
- $160–260
- Website
- Amtrak
Train from Quincy Amtrak Station to Chicago Union Station
- Ave. Duration
- 4h 21m
- Frequency
- Twice daily
- Estimated price
- $160–260
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Quincy Amtrak Station to La Grange Amtrak
- Ave. Duration
- 4h 1m
- Frequency
- Twice daily
- Estimated price
- $160–250
- Website
- Amtrak
- Phone
- +1 (866) 912 - 6224
- questions@coachusa.com
- Website
- Rockland Coaches
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 40m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- Rockland Coaches
- Adult
- $25–55
Bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 2h 55m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
Bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 2h 55m
- Frequency
- Hourly
- Estimated price
- $23–50
- Schedules at
- Rockland Coaches
- Adult
- $23–50
- Phone
- +1 414-266-4409
- ticketinfo@badgerbus.com
- Website
- Badger Bus
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $23–30
- Website
- Badger Bus
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h
- Frequency
- 5 times a day
- Estimated price
- $24–35
- Website
- Badger Bus
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $29–40
- Book at
- Jefferson Lines
- Adult
- $29–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $12–20
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $12–20
- Schedules at
- Flixbus USA
- Phone
- 920 496 3600
- Website
- example.com
Bus from Milwaukee, WI - Amtrak to Madison, WI-Lake St.
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $19–22
- Schedules at
- golamers.com
Bus from Mitchell Airport to Madison, WI-Lake St.
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $20–24
- Schedules at
- golamers.com
- Phone
- +1-888-875-6287
- Website
- Oats Transit
Shuttle from Hannibal to St. Louis
- Ave. Duration
- 1h 51m
- Frequency
- Twice a week
- Estimated price
- $4–7
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
Shuttle from Hannibal to St. Louis
- Ave. Duration
- 1h 51m
- Frequency
- Twice a week
- Estimated price
- $4–7
- Website
- Oats Transit
- Schedules at
- Oats Transit Schedules
- Ave. Duration
- 30 min
- Estimated price
- $75–95
Diamond Cab
- Phone
- +1-217-222-6700
Quincy Premium Transportation
- Phone
- +1 217-901-7433
- Website
- quincypremiumtransportation.com
Diamond Cab
- Phone
- +1-217-222-6700
Quincy Premium Transportation
- Phone
- +1 217-901-7433
- Website
- quincypremiumtransportation.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide











