There are 11 ways to get from Frederick to Key Largo by bus, plane, shuttle, bus (Greyhound, Flixbus), train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Baltimore-Washington International Airport, fly to Miami International Airport, shuttle
best- Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
- Fly from Baltimore-Washington International Airport (BWI) to Miami International Airport (MIA)plane BWI - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h$234–576Train, bus
cheapest- Take the train from FREDERICK MARC eb to Washington Union Stationtrain
- Take the train from Washington Union Station to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
29h 14m$128–369Bus
- Take the bus from Frederick Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Orlando Bus Stationbus
- Take the bus from Orlando Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
26h 39m$142–361Drive 1,149.1 mi
- Drive from Frederick to Key Largocar 1,149.1 mi
19h 14m$210–303Bus to Baltimore-Washington International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
- Fly from Baltimore-Washington International Airport (BWI) to Fort Lauderdale–Hollywood International Airport (FLL)plane BWI - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 25m$214–526Train to Ronald Reagan Washington National Airport, fly to Miami International Airport, shuttle
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Miami International Airport (MIA)plane DCA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 58m$226–930Train to Ronald Reagan Washington National Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Fort Lauderdale–Hollywood International Airport (FLL)plane DCA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
8h 13m$206–760Bus to Washington Dulles International Airport, fly to Miami International Airport, shuttle
- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Miami International Airport (MIA)plane IAD - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
8h 11m$164–556Bus to Washington Dulles International Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Frederick Transit Station to Market St & Harrison Stbus
- Fly from Washington Dulles International Airport (IAD) to Fort Lauderdale–Hollywood International Airport (FLL)plane IAD - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
8h 45m$274–646Bus to Baltimore-Washington International Airport, fly to Palm Beach International Airport, train, bus
- Take the bus from Frederick Bayrunner Office to Baltimore Airportbus
- Fly from Baltimore-Washington International Airport (BWI) to Palm Beach International Airport (PBI)plane BWI - PBI
- Take the train from West Palm Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
10h 40m$229–720Train, bus via Rockville
- Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain
- Take the train from Rockville Amtrak to Hollywood Amtrak Stationtrain
- Take the bus from Miami Airport Station to Key Largo Bus Stopbus
35h 5m$128–397
Frederick to Key Largo by bus
Questions & Answers
The cheapest way to get from Frederick to Key Largo is to bus which costs $140 - $370 and takes 26h 39m.
The fastest way to get from Frederick to Key Largo is to bus and fly and shuttle which takes 7h and costs $230 - $600.
No, there is no direct bus from Frederick station to Key Largo. However, there are services departing from Frederick Bus Station and arriving at Key Largo Bus Stop via Washington Union Station, Orlando Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 26h 39m.
The distance between Frederick and Key Largo is 1060 miles. The road distance is 1155.8 miles.
The best way to get from Frederick to Key Largo without a car is to bus which takes 26h 39m and costs $140 - $370.
It takes approximately 7h to get from Frederick to Key Largo, including transfers.
Frederick to Key Largo bus services, operated by Greyhound USA, depart from Frederick Bus Station.
Frederick to Key Largo bus services, operated by Greyhound USA, arrive at Washington Union Station.
Yes, the driving distance between Frederick to Key Largo is 1156 miles. It takes approximately 19h 14m to drive from Frederick to Key Largo.
Book your Frederick to Key Largo bus tickets online with Omio and FlixBus.
What companies run services between Frederick, MD, USA and Key Largo, FL, USA?
You can take a bus from Frederick Bus Station to Key Largo Bus Stop via Washington Union Station, Orlando Bus Station, and Miami Airport Station in around 26h 39m.
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Miami International Airport
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $80–430
Flights from Baltimore-Washington International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- $60–320
Flights from Ronald Reagan Washington National Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- $100–600
Flights from Baltimore-Washington International Airport to Palm Beach International Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $100–600
Flights from Baltimore-Washington International Airport to Palm Beach International Airport via Orlando
- Ave. Duration
- 4h 57m
- When
- Saturday and Sunday
- Estimated price
- $110–600
- Website
- aa.com
Flights from Baltimore-Washington International Airport to Miami International Airport
- Ave. Duration
- 3h 1m
- When
- Every day
- Estimated price
- $80–430
Flights from Ronald Reagan Washington National Airport to Miami International Airport
- Ave. Duration
- 3h 1m
- When
- Every day
- Estimated price
- $140–800
Flights from Ronald Reagan Washington National Airport to Miami International Airport via Savannah
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $150–800
Flights from Ronald Reagan Washington National Airport to Miami International Airport via Jacksonville
- Ave. Duration
- 4h 55m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
Flights from Ronald Reagan Washington National Airport to Miami International Airport via Greensboro/High Point
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $150–800
Flights from Ronald Reagan Washington National Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 48m
- When
- Every day
- Estimated price
- $100–600
Flights from Baltimore-Washington International Airport to Palm Beach International Airport via Charlotte
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $110–600
- Website
- flyfrontier.com
Flights from Baltimore-Washington International Airport to Miami International Airport
- Ave. Duration
- 2h 55m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $80–430
Flights from Baltimore-Washington International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 46m
- When
- Thursday and Sunday
- Estimated price
- $60–320
Flights from Washington Dulles International Airport to Miami International Airport
- Ave. Duration
- 2h 51m
- When
- Monday and Friday
- Estimated price
- $80–420
- Website
- jetblue.com
Flights from Ronald Reagan Washington National Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 45m
- When
- Every day
- Estimated price
- $100–600
- Website
- united.com
Flights from Washington Dulles International Airport to Miami International Airport
- Ave. Duration
- 3h 1m
- When
- Every day
- Estimated price
- $80–420
Flights from Washington Dulles International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- $55–310
- Website
- spirit.com
Flights from Baltimore-Washington International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 47m
- When
- Every day
- Estimated price
- $45–250
- Website
- delta.com
Flights from Ronald Reagan Washington National Airport to Miami International Airport
- Ave. Duration
- 2h 58m
- When
- Every day
- Estimated price
- $140–800
Flights from Ronald Reagan Washington National Airport to Fort Lauderdale–Hollywood International Airport via Raleigh/Durham
- Ave. Duration
- 6h 20m
- When
- Every day
- Estimated price
- $100–600
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from FREDERICK MARC eb to Washington Union Station
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $2–12
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–12
Train from FREDERICK MARC eb to ROCKVILLE MARC eb
- Ave. Duration
- 58 min
- Frequency
- Twice daily
- Estimated price
- $2–10
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–10
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to Hollywood Amtrak Station
- Ave. Duration
- 22h 57m
- Frequency
- Twice daily
- Estimated price
- $110–330
- Website
- https://www.amtrak.com/home.html
Train from Rockville Amtrak to Hollywood Amtrak Station
- Ave. Duration
- 29h 30m
- Frequency
- Once daily
- Estimated price
- $110–360
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $110–310
- Coach Seat short notice purchase
- $160–360
- Business - advance purchase
- $220–900
- Business Class
- $320–800
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- tri-rail.com
Train from West Palm Beach Station to Miami Airport Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
- Phone
- +1 410-912-6000
- reservations@bayrunnershuttle.com
- Website
- bayrunnershuttle.com
Bus from Frederick Bayrunner Office to Baltimore Airport
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $65–90
- Schedules at
- bayrunnershuttle.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Frederick Bus Station to Washington Union Station
- Ave. Duration
- 1h 10m
- Frequency
- 3 times a day
- Estimated price
- $11–20
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 6h 20m
- Frequency
- 3 times a day
- Estimated price
- $28–55
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $13–21
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Washington Union Station to Orlando Bus Station
- Ave. Duration
- 16h 25m
- Frequency
- 5 times a week
- Estimated price
- $90–260
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Miami Airport Station
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- $27–60
- Schedules at
- flixbus.com
- Phone
- +1 703-771-5665
- Website
- loudoun.gov
Bus from Frederick Transit Station to Market St & Harrison St
- Ave. Duration
- 58 min
- Frequency
- Once daily
- Estimated price
- $1–11
- Schedules at
- loudoun.gov
- Local & Metro
- $1–2
- Commuter
- $11
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