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How to get fromFrederick to Louisvilleby bus, plane, bus (Greyhound), train, car or bus (Greyhound, Flixbus)

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There are 8 ways to get from Frederick to Louisville by bus, plane, bus (Greyhound), train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Baltimore-Washington International Airport, fly to Louisville International Airport

    best
    1. Take the bus from Frederick Bayrunner Office to Baltimore Airportbus bus
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    5h 5m
    $210–740

  2. Bus

    cheapest
    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    13h 6m
    $83–164

  3. Train, bus

    1. Take the train from FREDERICK MARC eb to Washington Union Stationtrain train
    2. Take the train from Washington Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    24h 21m
    $124–307

  4. Drive 546.3 mi

    1. Drive from Frederick to Louisvillecar car 546.3 mi
    9h 38m
    $100–144

  5. Train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    6h 2m
    $147–973

  6. Train to Ronald Reagan Washington National Airport, fly to Blue Grass Airport, drive

    1. Take the train from FREDERICK MARC eb to ROCKVILLE MARC ebtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Blue Grass Airport (LEX)plane plane DCA - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    5h 49m
    $114–689

  7. Bus to Washington Dulles International Airport, fly to Louisville International Airport

    1. Take the bus from Frederick Transit Station to Market St & Harrison Stbus bus
    2. Fly from Washington Dulles International Airport (IAD) to Louisville International Airport (SDF)plane plane IAD - SDF
    6h 14m
    $245–509

  8. Bus via Columbus

    1. Take the bus from Frederick Bus Station to Pittsburgh Intermodal Stationbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Columbusbus bus
    3. Take the bus from Columbus - Downtown - Mound St to Louisville, KY Bus Stationbus bus
    13h 55m
    $85–152

Frederick to Louisville by train and bus

Calendar3Weekly Services
Duration24h 21mAverage Duration
Ticket$124Cheapest Price
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Questions & Answers

What companies run services between Frederick, MD, USA and Louisville, KY, USA?

You can take a bus from Frederick Bus Station to Louisville, KY Bus Station via Pittsburgh Intermodal Station and Columbus - Downtown - Mound St in around 13h 6m.

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