There are 8 ways to get from Chicago to Key Largo by plane, shuttle, bus (Flixbus, Greyhound), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Miami International Airport, shuttle
best- Fly from Chicago O'Hare International Airport (ORD) to Miami International Airport (MIA)ORD - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
7h 2m$132–405Bus
- Take the bus from Chicago Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Key Largo Bus Stop
32h$162–376Train, bus
- Take the train from Chicago Union Station to Hollywood Amtrak StationFloridian
- Take the bus from Miami Airport Station to Key Largo Bus StopGreyhound US0720s
2d 1h$328–595Drive 1,371.1 mi
- Drive from Chicago to Key Largo1,371.1 mi
24h 36m$251–362Fly Chicago Midway International Airport to Miami International Airport, shuttle
- Fly from Chicago Midway International Airport (MDW) to Miami International Airport (MIA)MDW - MIA
- Take a shuttle bus from Miami, FL - International Airport to Key Largo, FL
6h 47m$178–565Fly Chicago Midway International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Chicago Midway International Airport (MDW) to Fort Lauderdale–Hollywood International Airport (FLL)MDW - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 12m$172–485Fly Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Chicago O'Hare International Airport (ORD) to Fort Lauderdale–Hollywood International Airport (FLL)ORD - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FL
7h 32m$148–355Fly Chicago O'Hare International Airport to Key West International Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Key West International Airport (EYW)ORD - EYW
- Take the bus from Key West Airport to Key Largo Bus Stop
8h 45m$136–420
Chicago to Key Largo by bus
Questions & Answers
The cheapest way to get from Chicago to Key Largo is to fly and bus which costs $130 - $420 and takes 8h 45m.
The fastest way to get from Chicago to Key Largo is to fly and shuttle which takes 6h 47m and costs $170 - $600.
No, there is no direct bus from Chicago station to Key Largo. However, there are services departing from Chicago Bus Station and arriving at Key Largo Bus Stop via Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 32h.
The distance between Chicago and Key Largo is 1282 miles. The road distance is 1379.1 miles.
The best way to get from Chicago to Key Largo without a car is to bus which takes 32h and costs $160 - $380.
It takes approximately 7h 2m to get from Chicago to Key Largo, including transfers.
Chicago to Key Largo bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Key Largo bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Key Largo is 1h ahead of Chicago. It is currently 9:00 AM in Chicago and 10:00 AM in Key Largo.
Yes, the driving distance between Chicago to Key Largo is 1379 miles. It takes approximately 24h 36m to drive from Chicago to Key Largo.
What companies run services between Chicago, IL, USA and Key Largo, FL, USA?
You can take a bus from Chicago Bus Station to Key Largo Bus Stop via Atlanta Bus Station and Miami Airport Station in around 32h.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Miami International Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- $80–380
Flights from Chicago O'Hare International Airport to Miami International Airport via Jacksonville
- Ave. Duration
- 4h 47m
- When
- Saturday
- Estimated price
- $80–380
Flights from Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $60–280
Flights from Chicago O'Hare International Airport to Key West International Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $100–460
- Website
- southwest.com
Flights from Chicago Midway International Airport to Miami International Airport
- Ave. Duration
- 3h 2m
- When
- Every day
- Estimated price
- $95–450
Flights from Chicago Midway International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- $70–340
Flights from Chicago Midway International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 6h 35m
- When
- Monday to Friday
- Estimated price
- $70–340
Flights from Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $60–280
Flights from Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 5h
- When
- Saturday
- Estimated price
- $60–290
- Website
- spirit.com
Flights from Chicago O'Hare International Airport to Miami International Airport
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- $50–290
Flights from Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 11m
- When
- Every day
- Estimated price
- $45–210
Flights from Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport via Tampa
- Ave. Duration
- 4h 47m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $45–210
Flights from Chicago O'Hare International Airport to Key West International Airport via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 5h 20m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $110–380
- Website
- united.com
Flights from Chicago O'Hare International Airport to Miami International Airport
- Ave. Duration
- 3h 13m
- When
- Every day
- Estimated price
- $80–380
Flights from Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 10m
- When
- Every day
- Estimated price
- $60–280
Flights from Chicago O'Hare International Airport to Key West International Airport
- Ave. Duration
- 3h 19m
- When
- Every day
- Estimated price
- $100–460
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 3m
- When
- Every day
- Estimated price
- $100–460
- Website
- flyfrontier.com
Flights from Chicago Midway International Airport to Miami International Airport
- Ave. Duration
- 3h 10m
- When
- Wednesday, Thursday, and Saturday
- Estimated price
- $95–450
Flights from Chicago O'Hare International Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 16m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $60–280
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Hollywood Amtrak Station
- Ave. Duration
- 46h 6m
- Frequency
- Once daily
- Estimated price
- $310–600
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $80–110
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key Largo, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $100–140
- Website
- https://www.keysshuttle.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $85–160
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 15h 50m
- Frequency
- 4 times a day
- Estimated price
- $75–180
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $70–180
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Key Largo Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $13–22
- Website
- https://www.greyhound.com/
Bus from Key West Airport to Key Largo Bus Stop
- Ave. Duration
- 2h 40m
- Frequency
- Twice daily
- Estimated price
- $23–35
- Website
- https://www.greyhound.com/
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More Questions & Answers
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