There are 7 ways to get from Durham to Simpsonville by train, bus, car, plane, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain Piedmont / ...
- Take the bus from Charlotte, NC to Greenville, SCbus Nyc
5h 16m$112–143Drive 238.9 mi
cheapest- Drive from Durham to Simpsonvillecar 238.9 mi
4h 12m$44–63Train, bus via Taqueria Guadalajara - Greenville
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain Piedmont / ...
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus Charlotte
6h 52m$108–220Fly Raleigh-Durham International Airport to Greenville–Spartanburg International Airport
- Fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP)plane RDU - GSP
5h 34m$270–593Bus
- Take the bus from Durham to Charlotte Bus Stationbus FlixBus N2471 / ...
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus Charlotte
7h 5m$103–234Train to Charlotte Douglas International Airport, fly to Greenville–Spartanburg International Airport
- Take the train from Durham Amtrak Station to Charlotte Amtrak Stationtrain
- Fly from Charlotte Douglas International Airport (CLT) to Greenville–Spartanburg International Airport (GSP)plane CLT - GSP
5h 57m$258–628Fly Raleigh-Durham International Airport to Charlotte Douglas International Airport, bus
- Fly from Raleigh-Durham International Airport (RDU) to Charlotte Douglas International Airport (CLT)plane RDU - CLT
- Take the bus from Charlotte, NC to Greenville, SCbus
6h 30m$208–490
Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Durham to Simpsonville is to drive which costs $40 - $65 and takes 4h 12m.
The fastest way to get from Durham to Simpsonville is to drive which takes 4h 12m and costs $40 - $65.
The distance between Durham and Simpsonville is 253 miles. The road distance is 240.3 miles.
The best way to get from Durham to Simpsonville without a car is to train and bus which takes 5h 16m and costs $110 - $150.
It takes approximately 5h 16m to get from Durham to Simpsonville, including transfers.
The best way to get from Durham to Simpsonville is to fly which takes 5h 34m and costs $270 - $600. Alternatively, you can bus, which costs $100 - $240 and takes 7h 5m.
Yes, the driving distance between Durham to Simpsonville is 240 miles. It takes approximately 4h 12m to drive from Durham to Simpsonville.
There are 189+ hotels available in Simpsonville.
What companies run services between Durham, NC, USA and Simpsonville, SC, USA?
American Airlines, Delta, and two other airlines fly from Raleigh-Durham International Airport (RDU) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Durham to Simpsonville via Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 7h 5m.
- Website
- aa.com
Flights from Raleigh-Durham International Airport to Greenville–Spartanburg International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $60–430
Flights from Raleigh-Durham International Airport to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Raleigh-Durham International Airport to Greenville–Spartanburg International Airport via Philadelphia
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $120–650
Flights from Charlotte Douglas International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- $45–350
Flights from Raleigh-Durham International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $40–310
- Website
- delta.com
Flights from Raleigh-Durham International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Raleigh-Durham International Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $100–600
Flights from Raleigh-Durham International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 5h 22m
- When
- Thursday to Sunday
- Estimated price
- $100–600
- Website
- united.com
Flights from Raleigh-Durham International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 18m
- When
- Every day
- Estimated price
- $95–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Durham Amtrak Station to Charlotte Amtrak Station
- Ave. Duration
- 2h 38m
- Frequency
- 5 times a day
- Estimated price
- $31–33
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Charlotte, NC to Greenville, SC
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Durham to Charlotte Bus Station
- Ave. Duration
- 2h 35m
- Frequency
- 4 times a day
- Estimated price
- $26–45
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Durham to Charlotte Bus Station
- Ave. Duration
- 2h 45m
- Frequency
- 4 times a day
- Estimated price
- $26–40
- Website
- https://www.greyhound.com/
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