Rome2Rio

How to get fromOrlando to Simpsonvilleby plane, bus, car, bus (Flixbus, Greyhound) or bus (Flixbus)

Find Transport to Simpsonville

See all options

There are 9 ways to get from Orlando to Simpsonville by plane, bus, car, bus (Flixbus, Greyhound), or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Orlando to Greenville–Spartanburg International Airport

    best
    1. Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane plane MCO - GSP
    3h 28m
    $117–592
  2. Fly Orlando to Asheville Regional Airport, drive

    cheapest
    1. Fly from Orlando (MCO) to Asheville Regional Airport (AVL)plane plane MCO - AVL
    2. Drive from Asheville-Airport-AVL to Simpsonvillecar car
    4h 18m
    $58–299
  3. Bus

    1. Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus bus Orlando
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    13h 3m
    $115–339
  4. Drive 513.4 mi

    1. Drive from Orlando to Simpsonvillecar car 513.4 mi
    8h 24m
    $94–136
  5. Fly Orlando Sanford to Asheville Regional Airport, drive

    1. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    2. Drive from Asheville-Airport-AVL to Simpsonvillecar car
    3h 24m
    $122–420
  6. Fly Orlando Sanford to Greenville–Spartanburg International Airport

    1. Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane plane SFB - GSP
    2h 21m
    $156–533
  7. Bus to Tampa, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Orlando Bus Station to Tampa Bus Stationbus bus
    2. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    5h 37m
    $162–668
  8. Bus via Orlando Bus Station

    1. Take the bus from Orlando Bus Station to Atlanta Bus Stationbus bus FlixBus N2401 / ...
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    13h 11m
    $138–332
  9. Bus #2

    1. Take the bus from Orlando Bus Station to Charlotte Bus Stationbus bus FlixBus 2433
    2. Take the bus from Charlotte, NC to Greenville, SCbus bus Nyc
    13h 42m
    $125–195

Orlando (MCO) to Greenville–Spartanburg International Airport (GSP) flights

Calendar55Weekly Planes
Duration3h 36mAverage Duration
Ticket$62Cheapest Price
See schedules

Questions & Answers

What companies run services between Orlando, FL, USA and Simpsonville, SC, USA?

Breeze Airways, Delta, and American Airlines fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP) every 4 hours. Alternatively, you can take a bus from Orlando RedCoach Station to Simpsonville via Atlanta - Civic Center MARTA Station, Civic Center Station, Doraville Station, Doraville Station, Shallowford Rd @ New Peachtree Rd, Atlanta, and Taqueria Guadalajara - Greenville in around 13h 3m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound