There are 9 ways to get from Orlando to Simpsonville by plane, bus, car, bus (Flixbus, Greyhound), or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Orlando to Greenville–Spartanburg International Airport
best- Fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP)plane MCO - GSP
3h 28m$117–592Fly Orlando to Asheville Regional Airport, drive
cheapest- Fly from Orlando (MCO) to Asheville Regional Airport (AVL)plane MCO - AVL
- Drive from Asheville-Airport-AVL to Simpsonvillecar
4h 18m$58–299Bus
- Take the bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Stationbus Orlando
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus Charlotte
13h 3m$115–339Drive 513.4 mi
- Drive from Orlando to Simpsonvillecar 513.4 mi
8h 24m$94–136Fly Orlando Sanford to Asheville Regional Airport, drive
- Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane SFB - AVL
- Drive from Asheville-Airport-AVL to Simpsonvillecar
3h 24m$122–420Fly Orlando Sanford to Greenville–Spartanburg International Airport
- Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane SFB - GSP
2h 21m$156–533Bus to Tampa, fly to Greenville–Spartanburg International Airport
- Take the bus from Orlando Bus Station to Tampa Bus Stationbus
- Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane TPA - GSP
5h 37m$162–668Bus via Orlando Bus Station
- Take the bus from Orlando Bus Station to Atlanta Bus Stationbus FlixBus N2401 / ...
- Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus Charlotte
13h 11m$138–332Bus #2
- Take the bus from Orlando Bus Station to Charlotte Bus Stationbus FlixBus 2433
- Take the bus from Charlotte, NC to Greenville, SCbus Nyc
13h 42m$125–195
Orlando (MCO) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Orlando to Simpsonville is to drive which costs $90 - $140 and takes 8h 24m.
The fastest way to get from Orlando to Simpsonville is to fly which takes 2h 21m and costs $150 - $550.
The distance between Orlando and Simpsonville is 481 miles. The road distance is 516.4 miles.
The best way to get from Orlando to Simpsonville without a car is to bus which takes 13h 3m and costs $110 - $340.
It takes approximately 3h 28m to get from Orlando to Simpsonville, including transfers.
The best way to get from Orlando to Simpsonville is to fly which takes 3h 28m and costs $110 - $600. Alternatively, you can bus, which costs $110 - $340 and takes 13h 3m.
Yes, the driving distance between Orlando to Simpsonville is 516 miles. It takes approximately 8h 24m to drive from Orlando to Simpsonville.
There are 212+ hotels available in Simpsonville.
What companies run services between Orlando, FL, USA and Simpsonville, SC, USA?
Breeze Airways, Delta, and American Airlines fly from Orlando (MCO) to Greenville–Spartanburg International Airport (GSP) every 4 hours. Alternatively, you can take a bus from Orlando RedCoach Station to Simpsonville via Atlanta - Civic Center MARTA Station, Civic Center Station, Doraville Station, Doraville Station, Shallowford Rd @ New Peachtree Rd, Atlanta, and Taqueria Guadalajara - Greenville in around 13h 3m.
- Website
- delta.com
Flights from Orlando to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $60–370
Flights from Orlando to Asheville Regional Airport via Atlanta
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- $45–290
Flights from Tampa to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $70–430
- Website
- aa.com
Flights from Orlando to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $60–370
Flights from Orlando to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $45–290
Flights from Tampa to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $70–430
- Website
- allegiantair.com
Flights from Orlando Sanford to Asheville Regional Airport
- Ave. Duration
- 1h 33m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $50–330
Flights from Orlando to Asheville Regional Airport
- Ave. Duration
- 1h 47m
- When
- Thursday, Saturday, and Sunday
- Estimated price
- $45–280
Flights from Orlando Sanford to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 26m
- When
- Thursday and Sunday
- Estimated price
- $65–420
- Website
- flybreeze.com
Flights from Orlando to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 53m
- When
- Monday and Friday
- Estimated price
- $75–550
Flights from Tampa to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–480
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando RedCoach Station to Atlanta - Civic Center MARTA Station
- Ave. Duration
- 7h 15m
- Frequency
- Twice daily
- Estimated price
- $28–140
- Website
- https://www.redcoachusa.com
- Web
- $28–140
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Atlanta to Taqueria Guadalajara - Greenville
- Ave. Duration
- 3h 22m
- Frequency
- Once daily
- Estimated price
- $45–150
- Schedules at
- tornadobus.com
- Adults 11-59
- $45–150
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 1h 35m
- Frequency
- Every 4 hours
- Estimated price
- $10–17
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Atlanta Bus Station
- Ave. Duration
- 7h 25m
- Frequency
- Every 4 hours
- Estimated price
- $50–90
- Schedules at
- flixbus.com
Bus from Orlando Bus Station to Charlotte Bus Station
- Ave. Duration
- 10h
- Frequency
- Twice daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Orlando Bus Station to Tampa Bus Station
- Ave. Duration
- 2h 55m
- Frequency
- Once daily
- Estimated price
- $13–26
- Website
- https://www.greyhound.com/
Bus from Orlando Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Charlotte, NC to Greenville, SC
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
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