There are 5 ways to get from Myrtle Beach to Simpsonville by plane, bus (Greyhound, Flixbus), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP)plane MYR - GSP
3h 36m$270–652Drive 227.4 mi
cheapest- Drive from Myrtle Beach to Simpsonvillecar 227.4 mi
4h 32m$42–60Bus via Florence
- Take the bus from Myrtle Beach, SC to Florencebus
- Take the bus from Florence Bus Station to Charlotte Bus Stationbus
- Take the bus from Charlotte, NC to Greenville, SCbus Nyc
8h 6m$117–295Bus
- Take the bus from Myrtle Beach, SC to Charlotte Bus Stationbus Myrtle Beach
- Take the bus from Charlotte, NC to Greenville, SCbus Nyc
8h 51m$136–204Bus #2
- Take the bus from Myrtle Beach, SC to Charlotte Bus Stationbus Myrtle Beach
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus Charlotte
10h 44m$141–294
Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Myrtle Beach to Simpsonville is to drive which costs $40 - $60 and takes 4h 32m.
The fastest way to get from Myrtle Beach to Simpsonville is to fly which takes 3h 36m and costs $270 - $650.
The distance between Myrtle Beach and Simpsonville is 222 miles. The road distance is 228.7 miles.
The best way to get from Myrtle Beach to Simpsonville without a car is to bus via Florence which takes 8h 6m and costs $110 - $300.
It takes approximately 3h 36m to get from Myrtle Beach to Simpsonville, including transfers.
The best way to get from Myrtle Beach to Simpsonville is to fly which takes 3h 36m and costs $270 - $650. Alternatively, you can bus via Florence, which costs $110 - $300 and takes 8h 6m.
Yes, the driving distance between Myrtle Beach to Simpsonville is 229 miles. It takes approximately 4h 32m to drive from Myrtle Beach to Simpsonville.
There are 208+ hotels available in Simpsonville.
What companies run services between Myrtle Beach, SC, USA and Simpsonville, SC, USA?
American Airlines, Delta, and Southwest Airlines fly from Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP) every 3 hours. Alternatively, you can take a bus from Myrtle Beach, SC to Simpsonville via Florence, Florence Bus Station, Charlotte Bus Station, Charlotte, NC, and Greenville, SC in around 8h 6m.
- Website
- aa.com
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $55–400
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Reagan Washington
- Ave. Duration
- 4h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
- Website
- delta.com
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $75–460
- Website
- southwest.com
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $95–550
Flights from Myrtle Beach to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 6h 25m
- When
- Saturday
- Estimated price
- $100–550
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
Bus from Florence Bus Station to Charlotte Bus Station
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $30–100
- Schedules at
- southeasternstages.com
Bus from Myrtle Beach, SC to Charlotte Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- southeasternstages.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Myrtle Beach, SC to Florence
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $26–55
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Florence Bus Station to Charlotte Bus Station
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $19–60
- Schedules at
- flixbus.com
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Charlotte, NC to Greenville, SC
- Ave. Duration
- 1h 20m
- Frequency
- 3 times a day
- Estimated price
- $35–55
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
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