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How to get fromMyrtle Beach to Simpsonvilleby plane, bus (Greyhound) or car

Find Transport to Simpsonville

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There are 4 ways to get from Myrtle Beach to Simpsonville by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP)plane plane MYR - GSP
    3h 36m
    $350–652

  2. Drive 227.4 mi

    cheapest
    1. Drive from Myrtle Beach to Simpsonvillecar car 227.4 mi
    4h 32m
    $42–60

  3. Bus

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte, NC to Greenville, SCbus bus Nyc
    11h 31m
    $134–222

  4. Bus via Taqueria Guadalajara - Greenville

    1. Take the bus from Myrtle Beach Bus Station to Wilmington Cape Fear Public Transitbus bus
    2. Take the bus from Wilmington Cape Fear Public Transit to Charlotte Bus Stationbus bus
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    13h 24m
    $139–312

Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP) flights

Calendar56Weekly Planes
Duration4h 28mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Myrtle Beach, SC, USA and Simpsonville, SC, USA?

American Airlines, Delta, and Southwest Airlines fly from Myrtle Beach (MYR) to Greenville–Spartanburg International Airport (GSP) every 4 hours. Alternatively, you can take a bus from Myrtle Beach Bus Station to Simpsonville via Wilmington Cape Fear Public Transit, Charlotte Bus Station, Charlotte, NC, and Greenville, SC in around 11h 31m.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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