There are 4 ways to get from St. Louis to Pittsburgh by plane, bus, bus (Greyhound), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Lambert–St. Louis International Airport (STL) to Pittsburgh International Airport (PIT)STL - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
4h 29mBus (Greyhound)
cheapest- Take the bus from St Louis Bus Station to Pittsburgh Intermodal StationGreyhound US0421
12h 55m$80–190Train (Amtrak)
- Take the train from St. Louis to Chicago Union StationLincoln Service / ...
- Take the train from Chicago Union Station to Pittsburgh Amtrak StationFloridian
15h 20m$132–515Drive 598.4 mi
- Drive from St. Louis to Pittsburgh598.4 mi
9h 59m$110–158
St. Louis to Pittsburgh by bus (Greyhound)
Questions & Answers
The cheapest way to get from St. Louis to Pittsburgh is to bus which costs $80 - $190 and takes 12h 55m.
The fastest way to get from St. Louis to Pittsburgh is to drive which takes 9h 59m and costs $100 - $160.
Yes, there is a direct bus departing from St Louis Bus Station station and arriving at Pittsburgh Intermodal Station station. Services depart three times a day, and operate every day. The journey takes approximately 12h 55m.
No, there is no direct train from St. Louis to Pittsburgh station. However, there are services departing from St. Louis and arriving at Pittsburgh Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 15h 20m.
The distance between St. Louis and Pittsburgh is 594 miles. The road distance is 601.9 miles.
The best way to get from St. Louis to Pittsburgh without a car is to bus which takes 12h 55m and costs $80 - $190.
It takes approximately 4h 29m to get from St. Louis to Pittsburgh, including transfers.
St. Louis to Pittsburgh bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Pittsburgh train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Pittsburgh is to bus which takes 12h 55m and costs $80 - $190. Alternatively, you can train, which costs $130 - $550 and takes 15h 20m.
What companies run services between St. Louis, MO, USA and Pittsburgh, PA, USA?
Greyhound USA operates a bus from St Louis Bus Station to Pittsburgh Intermodal Station 3 times a day. Tickets cost $80–190 and the journey takes 12h 55m. Alternatively, you can take a train from St. Louis to Pittsburgh Amtrak Station via Chicago Union Station in around 15h 20m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport via Chicago Midway
- Ave. Duration
- 3h 35m
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport via Nashville
- Ave. Duration
- 4h 5m
- When
- Wednesday and Thursday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Pittsburgh International Airport via Detroit
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $110–600
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $40–320
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $90–200
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 412-442-2000
- Website
- rideprt.org
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Website
- https://www.rideprt.org
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 12h 55m
- Frequency
- 3 times a day
- Estimated price
- $80–190
- Website
- https://www.greyhound.com/
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More Questions & Answers
St. Louis to Pittsburgh bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Pittsburgh is 1h ahead of St. Louis. It is currently 11:23 PM in St. Louis and 12:23 AM in Pittsburgh.
St. Louis to Pittsburgh train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Pittsburgh is 602 miles. It takes approximately 9h 59m to drive from St. Louis to Pittsburgh.
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