Rome2Rio

How to get fromDenver to Chicagoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus or train

Find Transport to Chicago

See all options

There are 8 ways to get from Denver to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Denver to Chicago Midway International Airport

    best
    1. Fly from Denver (DEN) to Chicago Midway International Airport (MDW)plane plane DEN - MDW
    4h 46m
    $112–565

  2. Fly Denver to Chicago O'Hare International Airport

    cheapest
    1. Fly from Denver (DEN) to Chicago O'Hare International Airport (ORD)plane plane DEN - ORD
    5h 2m
    $67–325

  3. Train (Amtrak)

    1. Take the train from Denver to Chicago Union Stationtrain train California Zephyr
    18h 40m
    $290–650

  4. Bus

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus Greyhound US1200
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    23h 45m
    $194–356

  5. Drive 1,000.5 mi

    1. Drive from Denver to Chicagocar car 1,000.5 mi
    15h 53m
    $183–264

  6. Bus to Colorado Springs Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Denver, CO to Colorado Springs, CObus bus
    2. Fly from Colorado Springs Airport (COS) to Chicago O'Hare International Airport (ORD)plane plane COS - ORD
    7h 30m
    $79–345

  7. Bus to Colorado Springs Airport, fly to Chicago Midway International Airport

    1. Take the bus from Denver, CO to Colorado Springs, CObus bus
    2. Fly from Colorado Springs Airport (COS) to Chicago Midway International Airport (MDW)plane plane COS - MDW
    6h 58m
    $119–575

  8. Fly Denver to General Mitchell International Airport, train

    1. Fly from Denver (DEN) to General Mitchell International Airport (MKE)plane plane DEN - MKE
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    7h 4m
    $195–929

Denver to Chicago by train (Amtrak)

Calendar7Weekly Trains
Duration18h 40mAverage Duration
Ticket$290Cheapest Price
See schedules

Questions & Answers

What companies run services between Denver, CO, USA and Chicago, IL, USA?

Southwest Airlines flies from Denver (DEN) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, Amtrak operates a train from Denver to Chicago Union Station once daily. Tickets cost $290–650 and the journey takes 18h 40m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Where to next?

Trips from Denver

Trips to Chicago

Popular routes