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How to get fromDenver to Murphysboroby plane, bus, bus (Greyhound, Flixbus, Amtrak) or car

Find Transport to Murphysboro

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There are 5 ways to get from Denver to Murphysboro by plane, bus, bus (Greyhound, Flixbus, Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport, bus

    best
    1. Fly from Denver (DEN) to Lambert–St. Louis International Airport (STL)plane plane DEN - STL
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    7h 28m
    $164–786

  2. Bus

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus Greyhound US1200 / ...
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus FlixBus N2521
    19h 30m
    $172–342

  3. Drive 929.6 mi

    1. Drive from Denver to Murphysborocar car 929.6 mi
    15h 19m
    $170–246

  4. Fly to Nashville, bus

    1. Fly from Denver (DEN) to Nashville (BNA)plane plane DEN - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    10h 9m
    $417–1,180

  5. Fly to Williamson County Regional Airport

    1. Fly from Denver (DEN) to Williamson County Regional Airport (MWA)plane plane DEN - MWA
    7h 31m
    $175–670

Denver (DEN) to Lambert–St. Louis International Airport (STL) flights

Calendar69Weekly Planes
Duration2h 13mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

What companies run services between Denver, CO, USA and Murphysboro, IL, USA?

You can take a bus from Denver Union Station to Murphysboro via St Louis Bus Station and Carbondale Intermodal Station in around 19h 30m. Alternatively, United Airlines, Corporate Flight Management Inc, and American Airlines fly from Denver (DEN) to Williamson County Regional Airport (MWA) 3 times a day.

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