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How to get fromDenver to Murphysboroby plane, bus, bus (Greyhound, Amtrak, Flixbus), train (Amtrak) or car

Find Transport to Murphysboro

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There are 6 ways to get from Denver to Murphysboro by plane, bus, bus (Greyhound, Amtrak, Flixbus), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport, bus

    best
    1. Fly from Denver (DEN) to Lambert–St. Louis International Airport (STL)plane plane DEN - STL
    2. Take the bus from St. Louis to Carbondalebus bus
    7h 38m
    $183–886

  2. Fly to Williamson County Regional Airport

    cheapest
    1. Fly from Denver (DEN) to Williamson County Regional Airport (MWA)plane plane DEN - MWA
    7h 25m
    $150–550

  3. Bus

    1. Take the bus from Denver Union Station to St Louis Bus Stationbus bus Greyhound US1200
    2. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    19h 40m
    $176–336

  4. Train (Amtrak)

    1. Take the train from Denver to Chicago Union Stationtrain train California Zephyr
    2. Take the train from Chicago Union Station to Carbondaletrain train City of New Orleans / ...
    25h 6m
    $354–774

  5. Drive 930.2 mi

    1. Drive from Denver to Murphysborocar car 930.2 mi
    15h 25m
    $170–246

  6. Fly to Nashville, bus

    1. Fly from Denver (DEN) to Nashville (BNA)plane plane DEN - BNA
    2. Take the bus from Nashville Bus Station to Carbondale Intermodal Stationbus bus
    9h 54m
    $415–1,180

Denver (DEN) to Lambert–St. Louis International Airport (STL) flights

Calendar82Weekly Planes
Duration2h 25mAverage Duration
Ticket$141Cheapest Price
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Questions & Answers

What companies run services between Denver, CO, USA and Murphysboro, IL, USA?

You can take a bus from Denver Union Station to Murphysboro via St Louis Bus Station, St. Louis, and Carbondale in around 19h 40m. Alternatively, you can take a train from Denver to Murphysboro via Chicago Union Station and Carbondale in around 25h 6m.

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