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How to get fromDenver to Santa Anaby plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Find Transport to Santa Ana

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There are 7 ways to get from Denver to Santa Ana by plane, bus (Greyhound), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Denver (DEN) to John Wayne Airport Orange County (SNA)plane plane DEN - SNA
    4h 15m
    $209–523

  2. Fly to Long Beach Airport, bus

    cheapest
    1. Fly from Denver (DEN) to Long Beach Airport (LGB)plane plane DEN - LGB
    2. Take the bus from Long Beach Downtown Transit Gallery to Santa Ana Bus Stopbus bus
    7h 10m
    $70–342

  3. Bus (Greyhound)

    1. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus Greyhound US1200
    2. Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus bus Greyhound US0900
    22h
    $164–262

  4. Bus, train

    1. Take the bus from Denver to Las Vegas Transportation Centerbus bus Denver / ...
    2. Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain train Southwest Chief
    27h 9m
    $629–950

  5. Drive  1,013.3 mi

    1. Drive from Denver to Santa Anacar car 1,013.3 mi
    15h 51m
    $185–268

  6. Fly to Los Angeles International Airport, train

    1. Fly from Denver (DEN) to Los Angeles International Airport (LAX)plane plane DEN - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    6h 52m
    $160–541

  7. Bus via Artic - Dock 4

    1. Take the bus from Denver Union Station to Las Vegas Bus Terminalbus bus Greyhound US1200
    2. Take the bus from Las Vegas Strip to Anaheim Regional Transportation Intermodal Centerbus bus FlixBus 2030 / ...
    24h 8m
    $172–271

Denver to Santa Ana by bus (Greyhound)

Calendar7Weekly Buses
Duration22hAverage Duration
Ticket$164Cheapest Price
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Comparing Your Travel Options

Map of how to get from Denver to Santa Ana.ExpandLaunch map view
  • Distance: 873.1 mi
  • Duration: 4h 15m

What companies run services between Denver, CO, USA and Santa Ana, CA, USA?

Frontier Airlines, United Airlines, and two other airlines fly from Denver (DEN) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from Denver Union Station to Santa Ana Bus Stop via Las Vegas Bus Terminal in around 22h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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