There are 6 ways to get from Denver to Santa Ana by plane, bus (Greyhound), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to John Wayne Airport Orange County
best- Fly from Denver (DEN) to John Wayne Airport Orange County (SNA)plane DEN - SNA
4h 24m$139–645Fly to Long Beach Airport, bus
cheapest- Fly from Denver (DEN) to Long Beach Airport (LGB)plane DEN - LGB
- Take the bus from Long Beach Downtown Transit Gallery to Santa Ana Bus Stopbus
7h 25m$102–542Bus (Greyhound)
- Take the bus from Denver Union Station to Las Vegas Bus Terminalbus Greyhound US1200
- Take the bus from Las Vegas Bus Terminal to Santa Ana Bus Stopbus Greyhound US0900
22h$113–243Bus, train
- Take the bus from Denver to Las Vegas Transportation Centerbus Denver
- Take the train from Las Vegas Amtrak Station to Fullerton Amtrak Stationtrain Southwest Chief
27h 8m$166–389Drive 1,013.3 mi
- Drive from Denver to Santa Anacar 1,013.3 mi
15h 49m$185–268Fly to Los Angeles International Airport, train
- Fly from Denver (DEN) to Los Angeles International Airport (LAX)plane DEN - LAX
- Take the train from L.A. Union Station to Santa Anatrain
7h 33m$328–834
Denver to Santa Ana by bus (Greyhound)
Questions & Answers
The cheapest way to get from Denver to Santa Ana is to bus which costs $110 - $250 and takes 22h.
The fastest way to get from Denver to Santa Ana is to fly which takes 4h 24m and costs $130 - $650.
No, there is no direct bus from Denver station to Santa Ana. However, there are services departing from Denver Union Station and arriving at Santa Ana Bus Stop via Las Vegas Bus Terminal. The journey, including transfers, takes approximately 22h.
The distance between Denver and Santa Ana is 878 miles. The road distance is 1019.2 miles.
The best way to get from Denver to Santa Ana without a car is to bus which takes 22h and costs $110 - $250.
It takes approximately 4h 24m to get from Denver to Santa Ana, including transfers.
Denver to Santa Ana bus services, operated by Greyhound USA, depart from Denver Union Station.
The best way to get from Denver to Santa Ana is to fly which takes 4h 24m and costs $130 - $650. Alternatively, you can bus, which costs $110 - $250 and takes 22h.
Denver to Santa Ana bus services, operated by Greyhound USA, arrive at Las Vegas Bus Terminal station.
Santa Ana is 1h behind Denver. It is currently 7:44 AM in Denver and 6:44 AM in Santa Ana.
What companies run services between Denver, CO, USA and Santa Ana, CA, USA?
Frontier Airlines, United Airlines, and Southwest Airlines fly from Denver (DEN) to John Wayne Airport Orange County (SNA) every 2 hours. Alternatively, you can take a bus from Denver Union Station to Santa Ana Bus Stop via Las Vegas Bus Terminal in around 22h.
- Website
- southwest.com
Flights from Denver to John Wayne Airport Orange County
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $100–600
Flights from Denver to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $100–600
Flights from Denver to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $110–600
Flights from Denver to Los Angeles International Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $65–360
Flights from Denver to Los Angeles International Airport via Las Vegas
- Ave. Duration
- 4h 15m
- When
- Monday to Saturday
- Estimated price
- $65–360
Flights from Denver to Los Angeles International Airport via Phoenix
- Ave. Duration
- 4h 20m
- When
- Sunday
- Estimated price
- $70–370
Flights from Denver to Long Beach Airport
- Ave. Duration
- 2h 38m
- When
- Every day
- Estimated price
- $85–450
Flights from Denver to Long Beach Airport via Phoenix
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $90–470
Flights from Denver to Long Beach Airport via Las Vegas
- Ave. Duration
- 4h 51m
- When
- Thursday to Sunday
- Estimated price
- $85–450
Flights from Denver to Long Beach Airport via Reno
- Ave. Duration
- 4h 55m
- When
- Saturday
- Estimated price
- $100–550
Flights from Denver to Long Beach Airport via Sacramento
- Ave. Duration
- 5h 15m
- When
- Monday to Friday
- Estimated price
- $110–550
- Website
- united.com
Flights from Denver to John Wayne Airport Orange County
- Ave. Duration
- 2h 34m
- When
- Every day
- Estimated price
- $100–600
Flights from Denver to Los Angeles International Airport
- Ave. Duration
- 2h 39m
- When
- Every day
- Estimated price
- $65–360
- Website
- flyfrontier.com
Flights from Denver to John Wayne Airport Orange County
- Ave. Duration
- 2h 37m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Denver to Los Angeles International Airport
- Ave. Duration
- 2h 46m
- When
- Every day
- Estimated price
- $65–360
- Website
- delta.com
Flights from Denver to Los Angeles International Airport
- Ave. Duration
- 2h 50m
- When
- Every day
- Estimated price
- $65–360
- Website
- aa.com
Flights from Denver to Los Angeles International Airport
- Ave. Duration
- 2h 44m
- When
- Every day
- Estimated price
- $65–360
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Las Vegas Amtrak Station to Fullerton Amtrak Station
- Ave. Duration
- 20h 32m
- Frequency
- Twice daily
- Estimated price
- $90–290
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $90–250
- Coach Seat short notice purchase
- $120–290
- Business - advance purchase
- $170–700
- Business Class
- $260–650
- Phone
- (800) 371-LINK (5465)
- Website
- metrolinktrains.com
Train from L.A. Union Station to Santa Ana
- Ave. Duration
- 55 min
- Frequency
- Every 3 hours
- Estimated price
- $7–10
- Website
- https://metrolinktrains.com
- Passenger
- $7–10
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Denver Union Station to Las Vegas Bus Terminal
- Ave. Duration
- 15h 30m
- Frequency
- Once daily
- Estimated price
- $70–160
- Website
- https://www.greyhound.com/
Bus from Las Vegas Bus Terminal to Santa Ana Bus Stop
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Denver to Las Vegas Transportation Center
- Ave. Duration
- 4h 45m
- Frequency
- 3 times a day
- Estimated price
- $70–90
- Schedules at
- omnibusexpress.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Long Beach Downtown Transit Gallery to Santa Ana Bus Stop
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $5–80
- Schedules at
- flixbus.com
- Adult
- $5–80
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Denver to Santa Ana is 1019 miles. It takes approximately 15h 49m to drive from Denver to Santa Ana.
Book your Denver to Santa Ana bus tickets online with FlixBus.
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