There are 10 ways to get from Como to Isernia by train (Trenitalia), bus, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Como S.Giovanni to Milano Centraletrain S11
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Iserniatrain Re
7h 11m€55–132Bus
cheapest- Take the bus from Como to Roma, Autostazione Tiburtinabus 518 / ...
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus Rome Tiburtina
12h 50m€37–105Drive 770.3 km
- Drive from Como to Iserniacar 770.3 km
7h 20m€120–173Fly Milano Malpensa Airport to Naples Airport, train
- Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane MXP - NAP
- Take the train from Napoli Centrale to Iserniatrain
6h 57m€43–176Bus via Bologna
- Take the bus from Como to Bologna Centralebus 1524
- Take the bus from Bologna Centrale to Iserniabus 433
14h 4m€39–105Fly Milan Linate Airport to Naples Airport, train
- Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane LIN - NAP
- Take the train from Napoli Centrale to Iserniatrain
7h 18m€60–196Train, bus to Il Caravaggio International Airport, fly to Naples Airport
- Take the train from Como S. Giovanni to Milano Centraletrain
- Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus
- Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane BGY - NAP
- Take the train from Napoli Centrale to Iserniatrain
7h 29m€76–245Fly Milan Linate Airport to Fiumicino International Airport, train
- Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane LIN - FCO
- Take the train from Roma Termini to Iserniatrain
7h 33m€70–193Fly Milan Linate Airport to Foggia Gino Lisa Airport, bus
- Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane LIN - FOG
- Take the bus from Foggia to Iserniabus
7h 42m€120–395Fly Milano Malpensa Airport to Abruzzo Airport, bus
- Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane MXP - PSR
- Take the bus from Pescara to Iserniabus
8h 14m€44–195
Como to Isernia by train
Questions & Answers
The cheapest way to get from Como to Isernia is to bus which costs €35 - €110 and takes 12h 50m.
The fastest way to get from Como to Isernia is to fly and train which takes 6h 57m and costs €40 - €180.
No, there is no direct bus from Como to Isernia. However, there are services departing from Como and arriving at Isernia via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 12h 50m.
No, there is no direct train from Como to Isernia. However, there are services departing from Como S.Giovanni and arriving at Isernia via Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 7h 11m.
The distance between Como and Isernia is 795 km. The road distance is 770.3 km.
The best way to get from Como to Isernia without a car is to train which takes 7h 11m and costs €55 - €140.
It takes approximately 7h 11m to get from Como to Isernia, including transfers.
Como to Isernia bus services, operated by FlixBus, depart from Como station.
Como to Isernia train services, operated by Trenord, depart from Como S.Giovanni station.
The best way to get from Como to Isernia is to train which takes 7h 11m and costs €55 - €140. Alternatively, you can bus, which costs €35 - €110 and takes 12h 50m.
What companies run services between Como, Italy and Isernia, Italy?
You can take a train from Como S.Giovanni to Isernia via Milano Centrale and Roma Termini in around 7h 11m. Alternatively, you can take a bus from Como to Isernia via Roma, Autostazione Tiburtina in around 12h 50m.
- Website
- ryanair.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €40–150
Flights from Il Caravaggio International Airport to Naples Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- €45–170
Flights from Il Caravaggio International Airport to Naples Airport via Cagliari
- Ave. Duration
- 3h 40m
- When
- Monday and Sunday
- Estimated price
- €45–170
Flights from Milano Malpensa Airport to Abruzzo Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €26–150
- Website
- ita-airways.com
Flights from Milan Linate Airport to Naples Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- €40–170
Flights from Milan Linate Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 3h 3m
- When
- Every day
- Estimated price
- €40–170
Flights from Milan Linate Airport to Fiumicino International Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- €45–150
- Website
- easyjet.com
Flights from Milano Malpensa Airport to Naples Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- €26–140
- Website
- aeroitalia.com
Flights from Milan Linate Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €110–400
Flights from Milan Linate Airport to Foggia Gino Lisa Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €90–800
- Website
- flexflight.dk
Flights from Milan Linate Airport to Fiumicino International Airport via Olbia
- Ave. Duration
- 3h
- When
- Every day
- Estimated price
- €110–400
Flights from Milan Linate Airport to Foggia Gino Lisa Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €90–800
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Como S.Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €40–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €45–110
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €11–17
- Website
- https://www.trenitalia.com/en.html
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- €8–13
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Como S. Giovanni to Milano Centrale
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €22–40
- Website
- https://www.sbb.ch/en
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Como to Roma, Autostazione Tiburtina
- Ave. Duration
- 9h 40m
- Frequency
- Twice daily
- Estimated price
- €29–70
- Website
- https://www.flixbus.co.uk
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- €8–35
- Website
- https://www.flixbus.co.uk
Bus from Como to Bologna Centrale
- Ave. Duration
- 4h 40m
- Frequency
- 6 times a week
- Estimated price
- €16–35
- Website
- https://www.flixbus.co.uk
Bus from Bologna Centrale to Isernia
- Ave. Duration
- 8h 24m
- Frequency
- Twice daily
- Estimated price
- €23–70
- Website
- https://www.flixbus.co.uk
Bus from Foggia to Isernia
- Ave. Duration
- 2h 9m
- Frequency
- Once daily
- Estimated price
- €13–18
- Website
- https://www.flixbus.co.uk
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Twice daily
- Estimated price
- €14–35
- Website
- https://www.flixbus.co.uk
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Como to Roma, Autostazione Tiburtina
- Ave. Duration
- 9h 30m
- Frequency
- Once daily
- Estimated price
- €35–70
- Website
- https://marinobus.it/en/
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
- info@flibco.com
- Website
- flibco.com
Bus from Piazza Luigi di Savoia to Bergamo Airport Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 30 minutes
- Estimated price
- €8–10
- Website
- https://www.flibco.com/en
- Phone
- +39 02 3008 9000
- mail@autostradale.it
- Website
- autostradale.it
Bus from Piazza Luigi di Savoia to Bergamo Airport Bus Station
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €4–17
- Website
- https://autostradale.it/?lang=en-GB
- Standard Rate
- €13–17
Want to know more about travelling around Italy
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More Questions & Answers
Como to Isernia bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Como to Isernia train services, operated by Trenord, arrive at Milano Centrale station.
Yes, the driving distance between Como to Isernia is 770 km. It takes approximately 7h 20m to drive from Como to Isernia.
Book your Como to Isernia bus tickets online with Omio and FlixBus.
There are 394+ hotels available in Isernia.












































