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How to get fromComo to Iserniaby train (Trenitalia), bus, car, plane or train

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There are 10 ways to get from Como to Isernia by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Como S.Giovanni to Milano Centraletrain train S11
    2. Take the train from Milano Centrale to Roma Terminitrain train Fr / ...
    3. Take the train from Roma Termini to Iserniatrain train Re
    7h 11m
    €55–132
  2. Bus

    cheapest
    1. Take the bus from Como to Roma, Autostazione Tiburtinabus bus 518 / ...
    2. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus Rome Tiburtina
    12h 50m
    €37–105
  3. Drive 770.3 km

    1. Drive from Como to Iserniacar car 770.3 km
    7h 20m
    €120–173
  4. Fly Milano Malpensa Airport to Naples Airport, train

    1. Fly from Milano Malpensa Airport (MXP) to Naples Airport (NAP)plane plane MXP - NAP
    2. Take the train from Napoli Centrale to Iserniatrain train
    6h 57m
    €43–176
  5. Bus via Bologna

    1. Take the bus from Como to Bologna Centralebus bus 1524
    2. Take the bus from Bologna Centrale to Iserniabus bus 433
    14h 4m
    €39–105
  6. Fly Milan Linate Airport to Naples Airport, train

    1. Fly from Milan Linate Airport (LIN) to Naples Airport (NAP)plane plane LIN - NAP
    2. Take the train from Napoli Centrale to Iserniatrain train
    7h 18m
    €60–196
  7. Train, bus to Il Caravaggio International Airport, fly to Naples Airport

    1. Take the train from Como S. Giovanni to Milano Centraletrain train
    2. Take the bus from Piazza Luigi di Savoia to Bergamo Airport Bus Stationbus bus
    3. Fly from Il Caravaggio International Airport (BGY) to Naples Airport (NAP)plane plane BGY - NAP
    4. Take the train from Napoli Centrale to Iserniatrain train
    7h 29m
    €76–245
  8. Fly Milan Linate Airport to Fiumicino International Airport, train

    1. Fly from Milan Linate Airport (LIN) to Fiumicino International Airport (FCO)plane plane LIN - FCO
    2. Take the train from Roma Termini to Iserniatrain train
    7h 33m
    €70–193
  9. Fly Milan Linate Airport to Foggia Gino Lisa Airport, bus

    1. Fly from Milan Linate Airport (LIN) to Foggia Gino Lisa Airport (FOG)plane plane LIN - FOG
    2. Take the bus from Foggia to Iserniabus bus
    7h 42m
    €120–395
  10. Fly Milano Malpensa Airport to Abruzzo Airport, bus

    1. Fly from Milano Malpensa Airport (MXP) to Abruzzo Airport (PSR)plane plane MXP - PSR
    2. Take the bus from Pescara to Iserniabus bus
    8h 14m
    €44–195

Como to Isernia by train

Calendar35Weekly Trains
Duration7h 11mAverage Duration
Ticket€55Cheapest Price
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Questions & Answers

What companies run services between Como, Italy and Isernia, Italy?

You can take a train from Como S.Giovanni to Isernia via Milano Centrale and Roma Termini in around 7h 11m. Alternatively, you can take a bus from Como to Isernia via Roma, Autostazione Tiburtina in around 12h 50m.

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Bus operators

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