There are 12 ways to get from America to Isernia by train, plane, train (Trenitalia), bus, night train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Düsseldorf International Airport, fly to Naples Airport, train
best- Take the train from Venlo to Duesseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Naples Airport (NAP)plane DUS - NAP
- Take the train from Napoli Centrale to Iserniatrain
9h 14m€124–242Fly Weeze Airport to Abruzzo Airport, train, bus
cheapest- Fly from Weeze Airport (NRN) to Abruzzo Airport (PSR)plane NRN - PSR
- Take the train from Pescara Porta Nuova to Montenero-Petacciatotrain
- Take the bus from Montenero Bivio SS16 to Iserniabus
7h 34m€61–214Train
- Take the train from Venlo to Frankfurt(Main)Hbftrain Ice
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Centraletrain S11
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
19h 32m€387–1,020Train, bus
- Take the train from Venlo to Koeln Hbftrain Ice
- Take the train from Köln Hbf to Basel Bad Bftrain
- Take the bus from Basilea Badisher to Chietibus
- Take the bus from Chieti Scalo to Iserniabus
28h 16m€145–246Train, night train
- Take the train from Venlo to Frankfurt(M) Flughafen Fernbftrain Ice
- Take the train from Frankfurt to München Hbftrain 41 / ...
- Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain Nj
- Take the train from Roma Termini to Iserniatrain Re
25h 20m€168–612Train to Amsterdam Airport Schiphol, fly to Naples Airport, train
- Take the train from Horst-Sevenum to Schiphol Airport Train Stationtrain
- Fly from Amsterdam Airport Schiphol (AMS) to Naples Airport (NAP)plane AMS - NAP
- Take the train from Napoli Centrale to Iserniatrain
9h 40m€133–307Fly Eindhoven Airport to Fiumicino International Airport, train
- Fly from Eindhoven Airport (EIN) to Fiumicino International Airport (FCO)plane EIN - FCO
- Take the train from Roma Termini to Iserniatrain
8h 53m€112–297Train to Düsseldorf International Airport, fly to Fiumicino International Airport, train
- Take the train from Venlo to Duesseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO)plane DUS - FCO
- Take the train from Roma Termini to Iserniatrain
9h 35m€124–268Train, train to Brussels Airport, fly to Naples Airport
- Take the train from Eindhoven Centraal to Bredatrain
- Take the train from Breda to Brussels Airport-Zaventemtrain
- Fly from Brussels Airport (BRU) to Naples Airport (NAP)plane BRU - NAP
- Take the train from Napoli Centrale to Iserniatrain
10h 52m€120–284Bus
- Take the bus from Venlo Station to Essen central train stationbus 023
- Take the bus from Essen central train station to Florence Villa Constanza Bus Stationbus
- Take the bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtinabus 510 / ...
- Take the bus from Roma, Autostazione Tiburtina to Iserniabus
29h 29m€132–242Drive 1,629.7 km
- Drive from America to Iserniacar 1,629.7 km
15h 16m€295–425Drive, car train
- Drive from America to Fuldacar
- Take the car train from Fulda to Villach Hbfcartrain
- Drive from Villach Hbf to Iserniacar
22h 14m€287–410
Düsseldorf International Airport (DUS) to Naples Airport (NAP) flights
Questions & Answers
The cheapest way to get from America to Isernia is to fly and train and bus which costs €60 - €220 and takes 7h 34m.
The fastest way to get from America to Isernia is to fly and train and bus which takes 7h 34m and costs €60 - €220.
The distance between America and Isernia is 1511 km. The road distance is 1629.7 km.
The best way to get from America to Isernia without a car is to train which takes 19h 32m and costs €380 - €1100.
It takes approximately 9h 14m to get from America to Isernia, including transfers.
The best way to get from America to Isernia is to train which takes 19h 32m and costs €380 - €1100. Alternatively, you can bus, which costs €130 - €250 and takes 29h 29m.
Yes, the driving distance between America to Isernia is 1630 km. It takes approximately 15h 16m to drive from America to Isernia.
There are 460+ hotels available in Isernia.
What companies run services between America, Netherlands and Isernia, Italy?
You can take a vehicle from America to Isernia via Horst-Sevenum, Venlo, Frankfurt(Main)Hbf, Frankfurt, Chiasso, Milano Centrale, and Roma Termini in around 19h 32m. Alternatively, you can take a vehicle from America to Isernia via Sevenum, Berghemweg, Venlo Station, Essen central train station, Florence Villa Constanza Bus Station, and Roma, Autostazione Tiburtina in around 29h 29m.
- Website
- ita-airways.com
Flights from Düsseldorf International Airport to Naples Airport via Zurich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €90–330
Flights from Düsseldorf International Airport to Naples Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Monday and Sunday
- Estimated price
- €100–370
Flights from Düsseldorf International Airport to Naples Airport via Milan Linate
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–170
Flights from Amsterdam Airport Schiphol to Naples Airport via Milan Linate
- Ave. Duration
- 5h 45m
- When
- Monday to Friday
- Estimated price
- €90–200
Flights from Düsseldorf International Airport to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 45m
- When
- Monday to Friday
- Estimated price
- €75–170
Flights from Brussels Airport to Naples Airport via Milan Linate
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- €65–200
Flights from Brussels Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 4h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–200
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €80–390
Flights from Amsterdam Airport Schiphol to Naples Airport via Milan Linate
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- €80–390
- Website
- lufthansa.com
Flights from Düsseldorf International Airport to Naples Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Monday, Sunday, and Friday
- Estimated price
- €65–370
Flights from Düsseldorf International Airport to Naples Airport via Frankfurt
- Ave. Duration
- 4h 5m
- When
- Wednesday
- Estimated price
- €95–370
Flights from Düsseldorf International Airport to Fiumicino International Airport via Frankfurt
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- €90–340
- Website
- ryanair.com
Flights from Weeze Airport to Abruzzo Airport
- Ave. Duration
- 2h
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €35–180
Flights from Eindhoven Airport to Fiumicino International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €65–200
- Website
- transavia.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €80–390
- Website
- easyjet.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 28m
- When
- Tuesday, Monday, Wednesday, Sunday, and Friday
- Estimated price
- €70–240
- Website
- eurowings.com
Flights from Düsseldorf International Airport to Naples Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €80–170
Flights from Düsseldorf International Airport to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €75–170
- Website
- swiss.com
Flights from Düsseldorf International Airport to Naples Airport via Zurich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €90–330
Flights from Brussels Airport to Naples Airport via Zurich
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €85–320
- Website
- brusselsairlines.com
Flights from Brussels Airport to Naples Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €65–200
Flights from Brussels Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 4h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €65–200
- Website
- lufthansa-city.com
Flights from Düsseldorf International Airport to Naples Airport via Munich
- Ave. Duration
- 4h 5m
- When
- Monday and Friday
- Estimated price
- €65–320
- Website
- tuifly.be
Flights from Brussels Airport to Naples Airport
- Ave. Duration
- 2h 35m
- When
- Monday and Friday
- Estimated price
- €55–180
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 4m
- Frequency
- Every 30 minutes
- Estimated price
- €6–15
- Website
- https://www.ns.nl/en
Train from Venlo to Frankfurt(Main)Hbf
- Ave. Duration
- 2h 53m
- Frequency
- Hourly
- Estimated price
- €29–65
- Website
- https://www.ns.nl/en
Train from Venlo to Koeln Hbf
- Ave. Duration
- 1h 28m
- Frequency
- Hourly
- Estimated price
- €9–21
- Website
- https://www.ns.nl/en
Train from Köln Hbf to Basel Bad Bf
- Ave. Duration
- 6h 18m
- Frequency
- Once daily
- Estimated price
- €60–140
- Website
- https://www.ns.nl/en
Train from Venlo to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €28–65
- Website
- https://www.ns.nl/en
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 19m
- Frequency
- 4 times a day
- Estimated price
- €45–100
- Website
- https://www.ns.nl/en
Train from Horst-Sevenum to Schiphol Airport Train Station
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €18–40
- Website
- https://www.ns.nl/en
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 4m
- Frequency
- Every 30 minutes
- Estimated price
- €6–15
- Website
- https://www.ns.nl/en
Train from Eindhoven Centraal to Breda
- Ave. Duration
- 39 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–14
- Website
- https://www.ns.nl/en
Train from Breda to Brussels Airport-Zaventem
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €10–23
- Website
- https://www.ns.nl/en
- Phone
- 0180 6 9 27 37 27
- info@eurobahn.de
- Website
- eurobahn.de
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- https://www.eurobahn.de/en/
Train from Venlo to Duesseldorf Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- https://www.eurobahn.de/en/
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 5m
- Frequency
- Hourly
- Estimated price
- €16–26
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 5m
- Frequency
- Hourly
- Estimated price
- €16–26
- Website
- https://www.trenitalia.com/en.html
Train from Pescara Porta Nuova to Montenero-Petacciato
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- Hourly
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 5m
- Frequency
- Hourly
- Estimated price
- €16–26
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €230–700
- Website
- https://www.sbb.ch/en
Train from Chiasso to Milano Centrale
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €19–55
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Hourly
- Estimated price
- €70–140
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Venlo to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 37m
- Frequency
- Every 4 hours
- Estimated price
- €45–160
- Website
- https://int.bahn.de/en
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €75–250
- Website
- https://int.bahn.de/en
- Phone
- +49 221 800 20 80
- info@msm-gruppe.de
- Website
- msm-gruppe.de
Train from Frankfurt to München Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Once a week
- Schedules at
- msm-gruppe.de
- Phone
- +43 (0) 51717
- Website
- nightjet.com
Night train from Muenchen Hbf to Roma Tiburtina
- Ave. Duration
- 13h 58m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €110–140
- Couchette Carriage
- €85–100
- Seating Carriage
- €55–65
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Fulda to Villach Hbf
- Ave. Duration
- 9h 1m
- Frequency
- Once a week
- Estimated price
- €95–120
- Website
- https://urlaubs-express.de/?lang=en
- Phone
- +39 0825-26416
- INFORMAZIONI@BARTOLINIPULLMAN.IT
- Website
- bartolinipullman.it
Bus from Basilea Badisher to Chieti
- Ave. Duration
- 14h 15m
- Frequency
- Once a week
- Estimated price
- €50
- Schedules at
- bartolinipullman.it
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Chieti Scalo to Isernia
- Ave. Duration
- 2h 6m
- Frequency
- Twice daily
- Estimated price
- €8–12
- Schedules at
- atm-molise.it
Bus from Montenero Bivio SS16 to Isernia
- Ave. Duration
- 1h 23m
- Frequency
- Once daily
- Estimated price
- €5–8
- Schedules at
- atm-molise.it
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Venlo Station to Essen central train station
- Ave. Duration
- 1h 10m
- Frequency
- Twice daily
- Estimated price
- €4–8
- Website
- https://www.flixbus.co.uk
Bus from Essen central train station to Florence Villa Constanza Bus Station
- Ave. Duration
- 18h 55m
- Frequency
- 4 times a week
- Estimated price
- €90–150
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 15m
- Frequency
- Hourly
- Estimated price
- €20–35
- Website
- https://www.flixbus.co.uk
Bus from Roma, Autostazione Tiburtina to Isernia
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- €12–21
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- €17–35
- Website
- https://www.itabus.it/en/home
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 15m
- Frequency
- 6 times a week
- Estimated price
- €12–18
- Schedules at
- autoservizisalemi.it
- Phone
- +3 318 576 2228
- Website
- blablacar.co.uk
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- €22–40
- Website
- https://www.blablacar.co.uk/bus
- Phone
- +39 0972 24590
- booking@autolineemoretti.it
- Website
- autolineemoretti.it
Bus from Florence Villa Constanza Bus Station to Roma, Autostazione Tiburtina
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a week
- Estimated price
- €19–22
- Schedules at
- autolineemoretti.it
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