Rome2Rio

How to get fromAmerica to Iserniaby plane, bus, train (Trenitalia), train, night train, car or car train

Find Transport to Isernia

See all options

There are 12 ways to get from America to Isernia by plane, bus, train (Trenitalia), train, night train, car, or car train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Weeze Airport to Abruzzo Airport, bus

    best
    1. Fly from Weeze Airport (NRN) to Abruzzo Airport (PSR)plane plane NRN - PSR
    2. Take the bus from Pescara to Iserniabus bus
    7h 26m
    €65–372

  2. Train

    1. Take the train from Venlo to Duesseldorf Hbftrain train
    2. Take the train from Düsseldorf Hbf to München Hbftrain train 41 / ...
    3. Take the train from München Hbf to Verona Porta Nuovatrain train 89
    4. Take the train from Verona Porta Nuova to Roma Terminitrain train
    5. Take the train from Roma Termini to Iserniatrain train Re
    20h 46m
    €255–678

  3. Train, bus

    1. Take the train from Venlo to Duesseldorf Hbftrain train
    2. Take the train from Düsseldorf Hbf to Basel Bad Bftrain train 43N
    3. Take the bus from Basilea Badisher to Chietibus bus
    4. Take the bus from Chieti Scalo to Iserniabus bus
    28h 38m
    €192–273

  4. Train, night train

    1. Take the train from Venlo to Duesseldorf Hbftrain train
    2. Take the train from Düsseldorf Hbf to München Hbftrain train 41 / ...
    3. Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain night train Nj
    4. Take the train from Roma Tiburtina to Iserniatrain train Re
    25h 1m
    €165–488

  5. Train to Eindhoven Airport, fly to Fiumicino International Airport, train

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Fly from Eindhoven Airport (EIN) to Fiumicino International Airport (FCO)plane plane EIN - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    9h 3m
    €98–277

  6. Train to Düsseldorf International Airport, fly to Naples Airport, train

    1. Take the train from Venlo to Duesseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Naples Airport (NAP)plane plane DUS - NAP
    3. Take the train from Caserta to Iserniatrain train
    10h 4m
    €106–286

  7. Train to Düsseldorf International Airport, fly to Fiumicino International Airport, train

    1. Take the train from Venlo to Duesseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO)plane plane DUS - FCO
    3. Take the train from Roma Termini to Iserniatrain train
    9h 56m
    €121–289

  8. Train to Amsterdam Airport Schiphol, fly to Naples Airport, train

    1. Take the train from Horst-Sevenum to Schiphol Airport Train Stationtrain train
    2. Fly from Amsterdam Airport Schiphol (AMS) to Naples Airport (NAP)plane plane AMS - NAP
    3. Take the train from Caserta to Iserniatrain train
    10h 19m
    €108–285

  9. Train, train to Brussels Airport, fly to Naples Airport

    1. Take the train from Horst-Sevenum to Eindhoventrain train
    2. Take the train from Eindhoven to Bredatrain train
    3. Take the train from Breda to Brussels Airport-Zaventemtrain train
    4. Fly from Brussels Airport (BRU) to Naples Airport (NAP)plane plane BRU - NAP
    5. Take the train from Caserta to Iserniatrain train
    11h 19m
    €123–295

  10. Bus

    1. Take the bus from Mönchengladbach central train station to Mannheim central bus stationbus bus N94
    2. Take the bus from Mannheim central bus station to Roma, Autostazione Tiburtinabus bus N77
    3. Take the bus from Roma, Autostazione Tiburtina to Iserniabus bus
    29h 16m
    €137–240

  11. Drive 1,629.5 km

    1. Drive from America to Iserniacar car 1,629.5 km
    15h 16m
    €285–412

  12. Drive, car train

    1. Drive from America to Düsseldorf Hbfcar car
    2. Take the car train from Düsseldorf Hbf to Villach Hbfcartrain train
    3. Drive from Villach Hbf to Iserniacar car
    16h 14m
    €233–1,209

Weeze Airport (NRN) to Abruzzo Airport (PSR) flights

Calendar3Weekly Planes
Duration2hAverage Duration
Ticket€53Cheapest Price
See schedules

Questions & Answers

What companies run services between America, Netherlands and Isernia, Italy?

You can take a vehicle from America to Isernia via Horst-Sevenum, Venlo, Duesseldorf Hbf, Düsseldorf Hbf, München Hbf, Verona Porta Nuova, and Roma Termini in around 20h 46m. Alternatively, you can take a vehicle from America to Isernia via Sevenum, Berghemweg, Venlo, Mönchengladbach Hbf, Mönchengladbach central train station, Mannheim central bus station, and Roma, Autostazione Tiburtina in around 29h 16m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Trips from America

Trips to Isernia

Popular routes