There are 12 ways to get from America to Isernia by plane, bus, train (Trenitalia), train, night train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Weeze Airport to Abruzzo Airport, bus
best- Fly from Weeze Airport (NRN) to Abruzzo Airport (PSR)plane NRN - PSR
- Take the bus from Pescara to Iserniabus
7h 26m€65–244Train
- Take the train from Venlo to Frankfurt(Main)Hbftrain Ice
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Centraletrain S11
- Take the train from Milano Centrale to Roma Terminitrain
- Take the train from Roma Termini to Iserniatrain Re
19h 54m€389–1,033Bus
- Take the bus from Venlo Station to Düsseldorf Airportbus
- Take the bus from Duesseldorf Worringer Straße to Casello - A1 Ingresso Caianellobus
- Take the bus from Casello - A1 Ingresso Caianello to Iserniabus 6
27h 3mTrain, night train
- Take the train from Venlo to Frankfurt(M) Flughafen Fernbftrain Ice
- Take the train from Frankfurt to München Hbftrain 41 / ...
- Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain Nj
- Take the train from Roma Tiburtina to Iserniatrain Re
25h 41m€169–673Train to Düsseldorf International Airport, fly to Naples Airport, train
- Take the train from Venlo to Düsseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Naples Airport (NAP)plane DUS - NAP
- Take the train from Caserta to Iserniatrain
9h 58m€118–247Fly Eindhoven Airport to Fiumicino International Airport, train
- Fly from Eindhoven Airport (EIN) to Fiumicino International Airport (FCO)plane EIN - FCO
- Take the train from Roma Termini to Iserniatrain
9h 3m€112–310Train to Düsseldorf International Airport, fly to Fiumicino International Airport, train
- Take the train from Venlo to Düsseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO)plane DUS - FCO
- Take the train from Roma Termini to Iserniatrain
9h 56m€126–261Train to Amsterdam Airport Schiphol, fly to Naples Airport, train
- Take the train from Horst-Sevenum to Schiphol Airport Train Stationtrain
- Fly from Amsterdam Airport Schiphol (AMS) to Naples Airport (NAP)plane AMS - NAP
- Take the train from Caserta to Iserniatrain
10h 13m€127–311Train, train to Brussels Airport, fly to Naples Airport
- Take the train from Eindhoven Centraal to Bredatrain
- Take the train from Breda to Brussels Airport-Zaventemtrain
- Fly from Brussels Airport (BRU) to Naples Airport (NAP)plane BRU - NAP
- Take the train from Caserta to Iserniatrain
11h 23m€114–276Train, bus
- Take the train from Venlo to Frankfurt(Main)Hbftrain Ice
- Take the bus from Frankfurt central train station to Pescarabus
- Take the bus from Pescara to Iserniabus
27h 11m€155–286Drive 1,629.7 km
- Drive from America to Iserniacar 1,629.7 km
15h 16m€292–421Drive, car train
- Drive from America to Fuldacar
- Take the car train from Fulda to Villach Hbfcartrain
- Drive from Villach Hbf to Iserniacar
22h 14m€287–399
Weeze Airport (NRN) to Abruzzo Airport (PSR) flights
Questions & Answers
The cheapest way to get from America to Isernia is to fly and bus which costs €65 - €250 and takes 7h 26m.
The fastest way to get from America to Isernia is to fly and bus which takes 7h 26m and costs €65 - €250.
No, there is no direct bus from America to Isernia. However, there are services departing from Sevenum, Berghemweg and arriving at Isernia via Venlo Station, D-Flughafen Term. A/B/C, Duesseldorf Worringer Straße and Casello - A1 Ingresso Caianello. The journey, including transfers, takes approximately 27h 3m.
No, there is no direct train from America to Isernia. However, there are services departing from Horst-Sevenum and arriving at Isernia via Venlo, Frankfurt, Chiasso, Milano Centrale and Roma Termini. The journey, including transfers, takes approximately 19h 54m.
The distance between America and Isernia is 1402 km. The road distance is 1629.7 km.
The best way to get from America to Isernia without a car is to train which takes 19h 54m and costs €380 - €1100.
It takes approximately 7h 26m to get from America to Isernia, including transfers.
America to Isernia bus services, operated by FlixBus, depart from Venlo Station.
America to Isernia train services, operated by Nederlandse Spoorwegen (NS), depart from Venlo station.
The best way to get from America to Isernia is to train which takes 19h 54m and costs €380 - €1100. Alternatively, you can bus, which costs and takes 27h 3m.
What companies run services between America, Netherlands and Isernia, Italy?
You can take a vehicle from America to Isernia via Horst-Sevenum, Venlo, Frankfurt(Main)Hbf, Frankfurt, Chiasso, Milano Centrale, and Roma Termini in around 19h 54m. Alternatively, you can take a vehicle from America to Isernia via Sevenum, Berghemweg, Venlo Station, Düsseldorf Airport, D-Flughafen Term. A/B/C, Düsseldorf Hbf, Duesseldorf Worringer Straße, and Casello - A1 Ingresso Caianello in around 27h 3m.
- Website
- ita-airways.com
Flights from Düsseldorf International Airport to Naples Airport via Zurich
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €90–320
Flights from Düsseldorf International Airport to Naples Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Monday and Sunday
- Estimated price
- €95–350
Flights from Düsseldorf International Airport to Naples Airport via Milan Linate
- Ave. Duration
- 4h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €80–180
Flights from Düsseldorf International Airport to Fiumicino International Airport via Frankfurt
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €70–320
Flights from Düsseldorf International Airport to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 3h 45m
- When
- Monday to Friday
- Estimated price
- €70–170
Flights from Amsterdam Airport Schiphol to Naples Airport via Milan Linate
- Ave. Duration
- 5h 45m
- When
- Monday to Friday
- Estimated price
- €95–190
Flights from Brussels Airport to Naples Airport via Milan Linate
- Ave. Duration
- 3h 55m
- When
- Friday
- Estimated price
- €70–180
Flights from Brussels Airport to Naples Airport via Fiumicino International Airport
- Ave. Duration
- 4h 35m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- €75–200
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €80–390
Flights from Amsterdam Airport Schiphol to Naples Airport via Milan Linate
- Ave. Duration
- 4h 51m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €80–390
- Website
- lufthansa.com
Flights from Düsseldorf International Airport to Naples Airport via Munich
- Ave. Duration
- 3h 45m
- When
- Monday and Sunday
- Estimated price
- €95–350
Flights from Düsseldorf International Airport to Naples Airport via Frankfurt
- Ave. Duration
- 4h 5m
- When
- Wednesday
- Estimated price
- €95–350
Flights from Düsseldorf International Airport to Fiumicino International Airport via Frankfurt
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- €70–320
- Website
- ryanair.com
Flights from Weeze Airport to Abruzzo Airport
- Ave. Duration
- 2h
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- €50–200
Flights from Eindhoven Airport to Fiumicino International Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €60–210
- Website
- transavia.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- €80–390
- Website
- easyjet.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 27m
- When
- Tuesday, Monday, Wednesday, Sunday, and Friday
- Estimated price
- €70–230
- Website
- eurowings.com
Flights from Düsseldorf International Airport to Naples Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €80–180
Flights from Düsseldorf International Airport to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- €70–170
- Website
- swiss.com
Flights from Düsseldorf International Airport to Naples Airport via Zurich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €90–320
Flights from Brussels Airport to Naples Airport via Zurich
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- €85–300
- Website
- brusselsairlines.com
Flights from Brussels Airport to Naples Airport
- Ave. Duration
- 2h 20m
- When
- Every day
- Estimated price
- €75–200
- Website
- tuifly.be
Flights from Brussels Airport to Naples Airport
- Ave. Duration
- 2h 35m
- When
- Monday and Friday
- Estimated price
- €55–170
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Venlo to Frankfurt(Main)Hbf
- Ave. Duration
- 2h 53m
- Frequency
- Every 2 hours
- Estimated price
- €29–60
- Website
- https://www.ns.nl/en
Train from Venlo to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €28–60
- Website
- https://www.ns.nl/en
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 19m
- Frequency
- Twice daily
- Estimated price
- €45–95
- Website
- https://www.ns.nl/en
Train from Venlo to Düsseldorf Hbf
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €6–14
- Website
- https://www.ns.nl/en
Train from Venlo to Düsseldorf Hbf
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €6–14
- Website
- https://www.ns.nl/en
Train from Horst-Sevenum to Schiphol Airport Train Station
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €18–40
- Website
- https://www.ns.nl/en
Train from Eindhoven Centraal to Breda
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €6–14
- Website
- https://www.ns.nl/en
Train from Breda to Brussels Airport-Zaventem
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €10–22
- Website
- https://www.ns.nl/en
Train from Venlo to Frankfurt(Main)Hbf
- Ave. Duration
- 2h 53m
- Frequency
- Every 2 hours
- Estimated price
- €29–60
- Website
- https://www.ns.nl/en
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €230–700
- Website
- https://www.sbb.ch/en
Train from Chiasso to Milano Centrale
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €19–60
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 5m
- Frequency
- Every 30 minutes
- Estimated price
- €70–150
- Website
- https://www.italotreno.it/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Roma Tiburtina to Isernia
- Ave. Duration
- 2h 14m
- Frequency
- 6 times a week
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- 5 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €23–40
- Website
- https://www.trenitalia.com/en.html
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- 5 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Caserta to Isernia
- Ave. Duration
- 1h 17m
- Frequency
- 5 times a day
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Venlo to Frankfurt(M) Flughafen Fernbf
- Ave. Duration
- 2h 37m
- Frequency
- Every 4 hours
- Estimated price
- €45–180
- Website
- https://int.bahn.de/en
Train from Frankfurt to München Hbf
- Ave. Duration
- 3h 31m
- Frequency
- Hourly
- Estimated price
- €75–290
- Website
- https://int.bahn.de/en
- Phone
- +49 221 800 20 80
- info@msm-gruppe.de
- Website
- msm-gruppe.de
Train from Frankfurt to München Hbf
- Ave. Duration
- 4h 12m
- Frequency
- Once a week
- Schedules at
- msm-gruppe.de
- Phone
- +43 (0) 51717
- Website
- nightjet.com
Night train from Muenchen Hbf to Roma Tiburtina
- Ave. Duration
- 14h 6m
- Frequency
- 6 times a week
- Estimated price
- €55–140
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €110–140
- Couchette Carriage
- €85–100
- Seating Carriage
- €55–65
- Phone
- 0180 6 9 27 37 27
- info@eurobahn.de
- Website
- eurobahn.de
Train from Venlo to Düsseldorf Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- https://www.eurobahn.de/en/
Train from Venlo to Düsseldorf Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- https://www.eurobahn.de/en/
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Fulda to Villach Hbf
- Ave. Duration
- 9h 1m
- Frequency
- Once a week
- Estimated price
- €95–120
- Website
- https://urlaubs-express.de/?lang=en
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €14–23
- Website
- https://www.flixbus.co.uk
Bus from Venlo Station to Düsseldorf Airport
- Ave. Duration
- 50 min
- Frequency
- 6 times a week
- Estimated price
- €4–8
- Website
- https://www.flixbus.co.uk
Bus from Frankfurt central train station to Pescara
- Ave. Duration
- 18h 40m
- Frequency
- Once daily
- Estimated price
- €100–180
- Website
- https://www.flixbus.co.uk
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Once daily
- Estimated price
- €14–23
- Website
- https://www.flixbus.co.uk
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- onebus.it
Bus from Duesseldorf Worringer Straße to Casello - A1 Ingresso Caianello
- Ave. Duration
- 21h 5m
- Frequency
- Once a week
- Website
- https://onebus.it/
- Phone
- 0865.221788
- info@satiautobus.com
- Website
- satiautobus.com
Bus from Casello - A1 Ingresso Caianello to Isernia
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- €2–3
- Schedules at
- satiautobus.com
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More Questions & Answers
America to Isernia bus services, operated by FlixBus, arrive at Düsseldorf Airport station.
America to Isernia train services, operated by Nederlandse Spoorwegen (NS), arrive at Frankfurt(Main)Hbf station.
Yes, the driving distance between America to Isernia is 1630 km. It takes approximately 15h 16m to drive from America to Isernia.
There are 476+ hotels available in Isernia.









































