There are 14 ways to get from America to Isernia by train, plane, train (Eurostar, Trenitalia), bus, night train, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Amsterdam Airport Schiphol, fly to Naples Airport, train
best- Take the train from Horst-Sevenum to Schiphol Airporttrain
- Fly from Amsterdam Airport Schiphol (AMS) to Naples Airport (NAP)plane AMS - NAP
- Take the train from Napoli Centrale to Iserniatrain
9h 56m€119–296Train to Eindhoven Airport, fly to Fiumicino International Airport, train
cheapest- Take the train from Horst-Sevenum to Eindhoventrain
- Fly from Eindhoven Airport (EIN) to Fiumicino International Airport (FCO)plane EIN - FCO
- Take the train from Roma Termini to Iserniatrain
9h€108–348Train
- Take the train from Horst-Sevenum to Eindhoventrain
- Take the train from Eindhoven to Rotterdam Centraaltrain
- Take the train from Rotterdam Centraal to Chambery Challes Les Eauxtrain
- Take the train from Chambery Challes Les Eaux to Milano Centraletrain Fr
- Take the train from Milano Centrale to Roma Terminitrain Fr / ...
- Take the train from Roma Termini to Iserniatrain Re
19h 20m€349–730Bus
- Take the bus from Venlo Station to Frankfurt central train stationbus
- Take the bus from Frankfurt to Termolibus
- Take the bus from Termoli Terminal Bus to Iserniabus
26h 52m€143–191Train, night train
- Take the train from Venlo to Düsseldorf Hbftrain
- Take the train from Düsseldorf Hbf to München Hbftrain 41 / ...
- Take the night train from Muenchen Hbf to Roma Tiburtinanighttrain Nj
- Take the train from Roma Tiburtina to Iserniatrain Re
25h 7m€153–672Train to Düsseldorf International Airport, fly to Fiumicino International Airport, train
- Take the train from Venlo to Düsseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Fiumicino International Airport (FCO)plane DUS - FCO
- Take the train from Roma Termini to Iserniatrain
10h 3m€124–325Train, train to Cologne Bonn Airport, fly to Fiumicino International Airport
- Take the train from Venlo to Neuss Hbftrain
- Take the train from Neuss Hbf to Koeln/Bonn Flughafentrain
- Fly from Cologne Bonn Airport (CGN) to Fiumicino International Airport (FCO)plane CGN - FCO
- Take the train from Roma Termini to Iserniatrain
10h 33m€113–343Train, train to Brussels Airport, fly to Naples Airport
- Take the train from Horst-Sevenum to Eindhoventrain
- Take the train from Eindhoven to Bredatrain
- Take the train from Breda to Brussels Airport-Zaventemtrain
- Fly from Brussels Airport (BRU) to Naples Airport (NAP)plane BRU - NAP
- Take the train from Napoli Centrale to Iserniatrain
11h 7m€136–375Train, train to Brussels Airport, fly to Fiumicino International Airport
- Take the train from Horst-Sevenum to Eindhoventrain
- Take the train from Eindhoven to Bredatrain
- Take the train from Breda to Brussels Airport-Zaventemtrain
- Fly from Brussels Airport (BRU) to Fiumicino International Airport (FCO)plane BRU - FCO
- Take the train from Roma Termini to Iserniatrain
11h 18m€118–424Train, bus to Brussels South Charleroi Airport, fly to Naples Airport
- Take the train from Horst-Sevenum to Eindhoventrain
- Take the train from Eindhoven to Maastrichttrain
- Take the bus from Maastricht Meerssenerweg 231 to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Naples Airport (NAP)plane CRL - NAP
- Take the train from Napoli Centrale to Iserniatrain
12h 17m€129–299Train, bus to Brussels South Charleroi Airport, fly to Roma Ciampino Airport
- Take the train from Horst-Sevenum to Eindhoventrain
- Take the train from Eindhoven to Maastrichttrain
- Take the bus from Maastricht Meerssenerweg 231 to Charleroi Airportbus
- Fly from Brussels South Charleroi Airport (CRL) to Roma Ciampino Airport (CIA)plane CRL - CIA
- Take the train from Ciampino to Iserniatrain
12h 28m€119–307Train, bus
- Take the train from Venlo to Frankfurt(Main)Hbftrain Ice
- Take the bus from Frankfurt central train station to Pescarabus
- Take the bus from Pescara to Iserniabus
27h 28m€121–308Drive 1,629.4 km
- Drive from America to Iserniacar 1,629.4 km
15h 16m€283–409Drive, car train
- Drive from America to Düsseldorf Hbfcar
- Take the car train from Düsseldorf Hbf to Villach Hbfcartrain
- Drive from Villach Hbf to Iserniacar
16h 14m€233–1,209
Amsterdam Airport Schiphol (AMS) to Naples Airport (NAP) flights
Questions & Answers
The cheapest way to get from America to Isernia is to train and bus and fly which costs €110 - €310 and takes 12h 28m.
The fastest way to get from America to Isernia is to train and fly which takes 9h and costs €100 - €350.
The distance between America and Isernia is 1761 km. The road distance is 1629.4 km.
The best way to get from America to Isernia without a car is to train which takes 19h 20m and costs €340 - €750.
It takes approximately 9h 56m to get from America to Isernia, including transfers.
The best way to get from America to Isernia is to train which takes 19h 20m and costs €340 - €750. Alternatively, you can bus, which costs €140 - €200 and takes 26h 52m.
Yes, the driving distance between America to Isernia is 1629 km. It takes approximately 15h 16m to drive from America to Isernia.
There are 423+ hotels available in Isernia.
What companies run services between America, Netherlands and Isernia, Italy?
You can take a vehicle from America to Isernia via Horst-Sevenum, Eindhoven, Rotterdam Centraal, Chambery Challes Les Eaux, Milano Centrale, and Roma Termini in around 19h 20m. Alternatively, you can take a vehicle from America to Isernia via Sevenum, Berghemweg, Venlo Station, Frankfurt central train station, Frankfurt, and Termoli Terminal Bus in around 26h 52m.
- Website
- ryanair.com
Flights from Eindhoven Airport to Fiumicino International Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Wednesday, Saturday, and Sunday
- Estimated price
- €55–230
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 2h
- When
- Monday, Thursday, Saturday, and Sunday
- Estimated price
- €50–190
Flights from Brussels Airport to Fiumicino International Airport
- Ave. Duration
- 2h 10m
- When
- Monday, Friday, and Sunday
- Estimated price
- €40–140
Flights from Brussels South Charleroi Airport to Naples Airport
- Ave. Duration
- 2h 15m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- €60–240
Flights from Brussels South Charleroi Airport to Naples Airport via Milan Bergamo
- Ave. Duration
- 4h 21m
- When
- Monday, Tuesday, and Friday
- Estimated price
- €60–240
Flights from Brussels South Charleroi Airport to Roma Ciampino Airport
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €40–220
Flights from Brussels South Charleroi Airport to Roma Ciampino Airport via Bratislava
- Ave. Duration
- 4h 25m
- When
- Monday, Friday, and Sunday
- Estimated price
- €40–220
Flights from Brussels South Charleroi Airport to Roma Ciampino Airport via Cagliari
- Ave. Duration
- 5h 5m
- When
- Monday
- Estimated price
- €40–220
- Website
- ita-airways.com
Flights from Amsterdam Airport Schiphol to Naples Airport via Milan Linate
- Ave. Duration
- 4h 15m
- When
- Monday to Friday
- Estimated price
- €65–230
Flights from Düsseldorf International Airport to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 4h 10m
- When
- Monday to Saturday
- Estimated price
- €70–190
Flights from Düsseldorf International Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- €70–300
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 1h 55m
- When
- Friday
- Estimated price
- €65–190
Flights from Brussels Airport to Naples Airport via Milan Linate
- Ave. Duration
- 4h 27m
- When
- Monday to Saturday
- Estimated price
- €60–230
Flights from Brussels Airport to Fiumicino International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- €55–270
Flights from Brussels Airport to Fiumicino International Airport via Milan Linate
- Ave. Duration
- 4h 25m
- When
- Monday to Saturday
- Estimated price
- €55–270
- Website
- lufthansa.com
Flights from Düsseldorf International Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- €70–300
Flights from Cologne Bonn Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- €85–140
Flights from Brussels Airport to Naples Airport via Munich
- Ave. Duration
- 4h 40m
- When
- Friday and Sunday
- Estimated price
- €55–290
Flights from Brussels Airport to Fiumicino International Airport via Munich
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- €170–210
- Website
- brusselsairlines.com
Flights from Brussels Airport to Naples Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Thursday, and Sunday
- Estimated price
- €60–230
Flights from Brussels Airport to Fiumicino International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- €55–270
- Website
- klm.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 27m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- €70–380
Flights from Amsterdam Airport Schiphol to Naples Airport via Milan Linate
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €70–380
- Website
- easyjet.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €60–220
Flights from Brussels Airport to Naples Airport via Geneva
- Ave. Duration
- 4h
- When
- Friday
- Estimated price
- €75–180
Flights from Brussels Airport to Fiumicino International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- €35–160
- Website
- eurowings.com
Flights from Düsseldorf International Airport to Fiumicino International Airport
- Ave. Duration
- 2h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- €65–190
Flights from Cologne Bonn Airport to Fiumicino International Airport
- Ave. Duration
- 1h 55m
- When
- Friday
- Estimated price
- €65–190
- Website
- swiss.com
Flights from Brussels Airport to Fiumicino International Airport via Zurich
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- €60–250
- Website
- transavia.com
Flights from Amsterdam Airport Schiphol to Naples Airport
- Ave. Duration
- 2h 25m
- When
- Monday, Friday, and Sunday
- Estimated price
- €70–380
- Website
- tuifly.be
Flights from Brussels Airport to Naples Airport
- Ave. Duration
- 2h 35m
- When
- Friday
- Estimated price
- €80–270
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Horst-Sevenum to Schiphol Airport
- Ave. Duration
- 2h
- Frequency
- Hourly
- Estimated price
- €31
- Website
- https://www.ns.nl/en
Train from Horst-Sevenum to Eindhoven
- Ave. Duration
- 28 min
- Frequency
- Hourly
- Estimated price
- €10
- Website
- https://www.ns.nl/en
Train from Eindhoven to Rotterdam Centraal
- Ave. Duration
- 1h
- Frequency
- Every 30 minutes
- Estimated price
- €22–24
- Website
- https://www.ns.nl/en
Train from Venlo to Düsseldorf Hbf
- Ave. Duration
- 1h 4m
- Frequency
- Hourly
- Estimated price
- €11–35
- Website
- https://www.ns.nl/en
- 2nd Class
- €11–16
- 1st Class
- €18–35
Train from Düsseldorf Hbf to München Hbf
- Ave. Duration
- 4h 53m
- Frequency
- 3 times a day
- Estimated price
- €90–320
- Website
- https://www.ns.nl/en
- 2nd Class
- €90–140
- 1st Class
- €190–320
Train from Venlo to Neuss Hbf
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- €9–26
- Website
- https://www.ns.nl/en
- 2nd Class
- €9–14
- 1st Class
- €15–26
Train from Eindhoven to Breda
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €10–30
- Website
- https://www.ns.nl/en
- 2nd Class
- €10–16
- 1st Class
- €18–30
Train from Breda to Brussels Airport-Zaventem
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- €28–120
- Website
- https://www.ns.nl/en
Train from Eindhoven to Maastricht
- Ave. Duration
- 1h 3m
- Frequency
- Every 30 minutes
- Estimated price
- €20–23
- Website
- https://www.ns.nl/en
Train from Venlo to Frankfurt(Main)Hbf
- Ave. Duration
- 2h 53m
- Frequency
- Every 4 hours
- Estimated price
- €40–140
- Website
- https://www.ns.nl/en
- 2nd Class
- €40–60
- 1st Class
- €80–140
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Napoli Centrale to Isernia
- Ave. Duration
- 2h 3m
- Frequency
- 4 times a day
- Estimated price
- €8–14
- Website
- https://www.trenitalia.com/en.html
Train from Chambery Challes Les Eaux to Milano Centrale
- Ave. Duration
- 3h 21m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Isernia
- Ave. Duration
- 2h 8m
- Frequency
- 5 times a day
- Estimated price
- €13–60
- Website
- https://www.trenitalia.com/en.html
Train from Roma Tiburtina to Isernia
- Ave. Duration
- 2h 14m
- Frequency
- 6 times a week
- Estimated price
- €14
- Website
- https://www.trenitalia.com/en.html
Train from Ciampino to Isernia
- Ave. Duration
- 2h 6m
- Frequency
- Once a week
- Estimated price
- €13–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +44 343 218 6186
- Website
- eurostar.com
Train from Rotterdam Centraal to Chambery Challes Les Eaux
- Ave. Duration
- 5h 42m
- Frequency
- 3 times a week
- Estimated price
- €190–370
- Website
- https://www.eurostar.com/rw-en
- Standard
- €190–270
- Comfort
- €220–310
- Premium
- €280–370
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €45–110
- Schedules at
- trenitalia.com
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Roma Termini
- Ave. Duration
- 3h 39m
- Frequency
- Hourly
- Estimated price
- €45–100
- Website
- https://www.italotreno.it/en
- Phone
- 0180 6 9 27 37 27
- info@eurobahn.de
- Website
- eurobahn.de
Train from Venlo to Düsseldorf Hbf
- Ave. Duration
- 1h 5m
- Frequency
- Hourly
- Estimated price
- €13–18
- Website
- https://www.eurobahn.de/en/
Train from Venlo to Neuss Hbf
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- https://www.eurobahn.de/en/
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Düsseldorf Hbf to München Hbf
- Ave. Duration
- 4h 50m
- Frequency
- Hourly
- Estimated price
- €35–130
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Night train from Muenchen Hbf to Roma Tiburtina
- Ave. Duration
- 13h 58m
- Frequency
- Once daily
- Estimated price
- €75–280
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €260–280
- Couchette Carriage
- €160–190
- Seating Carriage
- €75–100
- Phone
- 0221 13 999 444
- Website
- nationalexpress.de
Train from Neuss Hbf to Koeln/Bonn Flughafen
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- €10–16
- Schedules at
- nationalexpress.de
- Phone
- 0800-0232 545
- Website
- arriva.nl
Train from Eindhoven to Maastricht
- Ave. Duration
- 1h 1m
- Frequency
- Once a week
- Estimated price
- €21–24
- Website
- https://www.arriva.nl/en/
- 2nd Class
- €21–24
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from Düsseldorf Hbf to Villach Hbf
- Ave. Duration
- 5h 53m
- Frequency
- Once a week
- Estimated price
- €100–1,000
- Website
- https://urlaubs-express.de/?lang=en
- Car Single Bed
- €270–550
- Car Compartment
- €550–1,000
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Venlo Station to Frankfurt central train station
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- €20–40
- Website
- https://www.flixbus.co.uk
Bus from Frankfurt central train station to Pescara
- Ave. Duration
- 18h 40m
- Frequency
- Twice daily
- Estimated price
- €55–110
- Website
- https://www.flixbus.co.uk
Bus from Pescara to Isernia
- Ave. Duration
- 2h 29m
- Frequency
- Twice daily
- Estimated price
- €13–35
- Website
- https://www.flixbus.co.uk
- Phone
- +39 098 3520 315
- info@fsbusitaliafast.it
- Website
- simetbus.it
Bus from Frankfurt to Termoli
- Ave. Duration
- 15h 57m
- Frequency
- Once a week
- Estimated price
- €100–120
- Schedules at
- simetbus.it
- Phone
- +39 0874 64744
- info@atm-molise.it
- Website
- atm-molise.it
Bus from Termoli Terminal Bus to Isernia
- Ave. Duration
- 1h 35m
- Frequency
- Once a week
- Estimated price
- €5–8
- Schedules at
- atm-molise.it
Bus from Pescara to Isernia
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- €8–13
- Schedules at
- atm-molise.it
- info@flibco.com
- Website
- flibco.com
Bus from Maastricht Meerssenerweg 231 to Charleroi Airport
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- €16–20
- Website
- https://www.flibco.com/en
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