There are 9 ways to get from Chicago to Missouri by plane, train (Amtrak), bus (Greyhound), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
3h 44m$246–558Bus
cheapest- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123 / ...
- Take the bus from Des Moines to Kansas Citybus Jefferson 803 / ...
11h 4m$62–170Train (Amtrak)
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
7h 35m$65–150Drive 506.6 mi
- Drive from Chicago to Kansas Citycar 506.6 mi
8h 37m$93–134Subway to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
3h 24m$106–758Fly Chicago O'Hare International Airport to Columbia Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
3h 32m$92–340Fly Chicago O'Hare International Airport to Springfield-Branson National Airport
- Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)plane ORD - SGF
3h 47m$108–625Subway to Chicago Midway International Airport, fly to Kansas City
- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane MDW - MCI
4h 37m$92–605Fly Chicago O'Hare International Airport to Kansas City
- Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)plane ORD - MCI
5h 4m$132–605
Chicago to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Missouri is to train which costs $65 - $150 and takes 7h 35m.
The fastest way to get from Chicago to Missouri is to subway and fly which takes 3h 24m and costs $100 - $800.
No, there is no direct bus from Chicago station to Missouri. However, there are services departing from Chicago Bus Station and arriving at Kansas City via Des Moines. The journey, including transfers, takes approximately 11h 4m.
No, there is no direct train from Chicago station to Missouri. However, there are services departing from Chicago Union Station and arriving at Metro Center via Union Station. The journey, including transfers, takes approximately 7h 35m.
The distance between Chicago and Missouri is 292 miles. The road distance is 509.6 miles.
The best way to get from Chicago to Missouri without a car is to train which takes 7h 35m and costs $65 - $150.
It takes approximately 3h 44m to get from Chicago to Missouri, including transfers.
Chicago to Missouri bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Missouri train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Missouri is to fly which takes 3h 44m and costs $240 - $600. Alternatively, you can train, which costs $65 - $150 and takes 7h 35m, you could also bus, which costs $60 - $170 and takes 11h 4m.
What companies run services between Chicago, IL, USA and Missouri, USA?
American Airlines, GoJet Airlines, and United Airlines fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Amtrak operates a train from Chicago Union Station to Kansas City twice daily. Tickets cost $65–150 and the journey takes 7h 23m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $100–750
Flights from Chicago Midway International Airport to Kansas City
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $90–600
Flights from Chicago Midway International Airport to Kansas City via Lambert–St. Louis International Airport
- Ave. Duration
- 3h 15m
- When
- Tuesday
- Estimated price
- $100–600
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $70–550
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $90–600
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $65–410
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $70–550
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $90–600
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 47m
- When
- Every day
- Estimated price
- $65–410
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $70–550
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Kansas City via Minneapolis
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $85–480
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $65–150
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 34m
- Frequency
- 3 times a day
- Estimated price
- $40–80
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Want to know more about travelling around United States
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More Questions & Answers
Chicago to Missouri bus services, operated by Greyhound USA, arrive at Des Moines station.
Chicago to Missouri train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Chicago to Missouri is 510 miles. It takes approximately 8h 37m to drive from Chicago to Missouri.
There are 342+ hotels available in Missouri.