There are 10 ways to get from Chicago to Missouri by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Chicago O'Hare to Columbia  •  3 h 10 min

  1. Fly from Chicago O'Hare (ORD) to Columbia (COU) ORD - COU

$177 - $390

Cheapest option

Bus Greyhound USA  •  10 h 31 min

  1. Take the bus from Chicago, Il to St Louis, Mo 1353
  2. Take the bus from St Louis, Mo to Kansas City, Mo 1683 / ...

$64 - $153

8 alternative options

Fly Chicago O'Hare to Springfield  •  3 h 27 min

  1. Fly from Chicago O'Hare (ORD) to Springfield (SGF) ORD - SGF

$178 - $385

Fly Chicago Midway to St. Louis, line 34 bus  •  3 h 30 min

  1. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL
  2. Take the line 34 bus from North Hanley Transit Center to Earth City Expy @ Pattonville Fire Station Nb

$127 - $309

Fly Chicago O'Hare to St. Louis, line 34 bus  •  3 h 45 min

  1. Fly from Chicago O'Hare (ORD) to St. Louis (STL) ORD - STL
  2. Take the line 34 bus from North Hanley Transit Center to Earth City Expy @ Pattonville Fire Station Nb

$92 - $250

Fly Chicago Midway to Kansas City  •  4 h 21 min

  1. Fly from Chicago Midway (MDW) to Kansas City (MCI) MDW - MCI

$114 - $286

Fly Chicago O'Hare to Kansas City  •  4 h 36 min

  1. Fly from Chicago O'Hare (ORD) to Kansas City (MCI) ORD - MCI

$114 - $267

Train  •  7 h 23 min

  1. Take the train from Chicago Union Station Amtrak to Kansas City Amtrak Southwest Chief

$65 - $190

Bus Burlington Trailways  •  10 h 26 min

  1. Take the bus from Chicago, IL to Des Moines, IA 1202 / ...
  2. Take the bus from Des Moines, IA to Kansas City, MO 803 / ...

$96 - $133

Drive  •  8 h 38 min

  1. Drive from Chicago to Kansas City 528.5 miles

$50 - $75

Questions & Answers

The cheapest way to get from Chicago to Missouri is to drive which costs $50 - $75 and takes 8 h 38 min.

More details

The quickest way to get from Chicago to Missouri is to fly which costs $170 - $390 and takes 3 h 10 min.

More details

The distance between Chicago and Missouri is 339 miles. The road distance is 528.5 miles.

Get driving directions

It takes approximately 3 h 10 min to get from Chicago to Missouri, including transfers.

More details

No, there is no direct bus from Chicago to Missouri. However, there are services departing from Chicago, IL and arriving at Kansas City, MO via Des Moines, IA. The journey, including transfers, takes approximately 10 h 26 min.

More details

Yes, there is a direct train departing from Chicago Union Station Amtrak station and arriving at Kansas City Amtrak. Services depart once daily, and operate every day. The journey takes approximately 7 h 23 min.

More details

What companies run services between Chicago, IL, USA and Missouri, USA?

American Airlines and United Airlines fly from Chicago to Columbia 4 times a day. Alternatively, Amtrak operates a train from Chicago to Kansas City once daily. Tickets cost $65 - $190 and the journey takes 7 h 23 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$160 - $550
Flights from Chicago Midway to Kansas City
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$140 - $600
Flights from Chicago Midway to Kansas City via St. Louis
Ave. Duration
2 h 57 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$140 - $600
United Airlines
Website
united.com
Flights from Chicago O'Hare to Columbia
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$190 - $950
Flights from Chicago O'Hare to Springfield
Ave. Duration
1 h 48 min
When
Every day
Estimated price
$320 - $750
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$120 - $650
Flights from Chicago O'Hare to Kansas City
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$110 - $550
American Airlines
Website
aa.com
Flights from Chicago O'Hare to Columbia
Ave. Duration
1 h 13 min
When
Every day
Estimated price
$290 - $650
Flights from Chicago O'Hare to Springfield
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$330 - $700
Flights from Chicago O'Hare to St. Louis
Ave. Duration
1 h 6 min
When
Every day
Estimated price
$120 - $550
Flights from Chicago O'Hare to Kansas City
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$110 - $480
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Chicago Union Station Amtrak to Kansas City Amtrak
Ave. Duration
7 h 23 min
Frequency
Once daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Bus operators
Metro St. Louis
Phone
+1 314-982-1400
Website
metrostlouis.org
Bus from North Hanley Transit Center to Earth City Expy @ Pattonville Fire Station Nb
Ave. Duration
17 min
Frequency
Hourly
Estimated price
$2
Schedules at
metrostlouis.org
Burlington Trailways
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Des Moines, IA to Kansas City, MO
Ave. Duration
3 h 10 min
Frequency
Hourly
Estimated price
$40 - $55
Schedules at
jeffersonlines.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Chicago, Il to St Louis, Mo
Ave. Duration
5 h 45 min
Frequency
Hourly
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Bus from St Louis, Mo to Kansas City, Mo
Ave. Duration
4 h 25 min
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70

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