There are 9 ways to get from Chicago to Missouri by subway, plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
best- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
3h 24m$106–708Fly Chicago O'Hare International Airport to Springfield-Branson National Airport
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)plane ORD - SGF
3h 49m$58–295Train (Amtrak)
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
7h 35m$120–280Bus
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0155S
- Take the bus from Des Moines to Kansas Citybus Jefferson 803 / ...
12h 55m$80–205Drive 506.6 mi
- Drive from Chicago to Kansas Citycar 506.6 mi
8h 37m$93–134Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
3h 47m$256–498Fly Chicago O'Hare International Airport to Columbia Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
3h 35m$88–320Subway to Chicago Midway International Airport, fly to Kansas City
- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane MDW - MCI
4h 41m$92–605Fly Chicago O'Hare International Airport to Kansas City
- Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)plane ORD - MCI
5h 13m$262–555
Chicago to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Missouri is to drive which costs $90 - $140 and takes 8h 37m.
The fastest way to get from Chicago to Missouri is to subway and fly which takes 3h 24m and costs $100 - $750.
No, there is no direct bus from Chicago station to Missouri. However, there are services departing from Chicago Bus Station and arriving at Kansas City via Des Moines. The journey, including transfers, takes approximately 12h 55m.
No, there is no direct train from Chicago station to Missouri. However, there are services departing from Chicago Union Station and arriving at Metro Center via Union Station. The journey, including transfers, takes approximately 7h 35m.
The distance between Chicago and Missouri is 278 miles. The road distance is 509.6 miles.
The best way to get from Chicago to Missouri without a car is to train which takes 7h 35m and costs $120 - $280.
It takes approximately 3h 24m to get from Chicago to Missouri, including transfers.
Chicago to Missouri bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Chicago to Missouri train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Missouri is to train which takes 7h 35m and costs $120 - $280. Alternatively, you can bus, which costs $80 - $210 and takes 12h 55m, you could also fly, which costs $250 - $500 and takes 3h 47m.
What companies run services between Chicago, IL, USA and Missouri, USA?
Amtrak operates a train from Chicago Union Station to Kansas City twice daily. Tickets cost $120–280 and the journey takes 7h 23m. Alternatively, you can take a bus from Chicago Bus Station to Kansas City via Des Moines in around 12h 55m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $70–490
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $35–250
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $60–390
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $70–490
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $35–250
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 53m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 48m
- When
- Every day
- Estimated price
- $60–390
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $100–700
Flights from Chicago Midway International Airport to Kansas City
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $90–600
Flights from Chicago Midway International Airport to Kansas City via Lambert–St. Louis International Airport
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $100–600
Flights from Chicago Midway International Airport to Kansas City via Indianapolis
- Ave. Duration
- 3h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–650
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $70–490
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $120–280
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $60–120
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Want to know more about travelling around United States
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More Questions & Answers
Chicago to Missouri bus services, operated by Greyhound USA, arrive at Des Moines station.
Chicago to Missouri train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Chicago to Missouri is 510 miles. It takes approximately 8h 37m to drive from Chicago to Missouri.
There are 1165+ hotels available in Missouri.