There are 8 ways to get from Chicago to Missouri by plane, train (Amtrak), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
3h 44m$256–458Fly Chicago O'Hare International Airport to Springfield-Branson National Airport
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)plane ORD - SGF
3h 47m$58–295Train (Amtrak)
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
7h 23m$110–250Drive 506.6 mi
- Drive from Chicago to Kansas Citycar 506.6 mi
8h 37m$93–134Fly Chicago O'Hare International Airport to Columbia Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
3h 30m$88–320Subway to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
3h 29m$106–758Subway to Chicago Midway International Airport, fly to Kansas City
- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane MDW - MCI
4h 41m$88–605Fly Chicago O'Hare International Airport to Kansas City
- Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)plane ORD - MCI
5h 7m$262–555
Chicago to Missouri by train (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Missouri is to drive which costs $90 - $140 and takes 8h 37m.
The fastest way to get from Chicago to Missouri is to subway and fly which takes 3h 29m and costs $100 - $800.
Yes, there is a direct train departing from Chicago Union Station station and arriving at Kansas City. Services depart twice daily, and operate every day. The journey takes approximately 7h 23m.
The distance between Chicago and Missouri is 292 miles. The road distance is 509.6 miles.
The best way to get from Chicago to Missouri without a car is to train which takes 7h 23m and costs $110 - $250.
It takes approximately 3h 44m to get from Chicago to Missouri, including transfers.
Chicago to Missouri train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Missouri is to fly which takes 3h 44m and costs $250 - $460. Alternatively, you can train, which costs $110 - $250 and takes 7h 23m.
Chicago to Missouri train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Chicago to Missouri is 510 miles. It takes approximately 8h 37m to drive from Chicago to Missouri.
What companies run services between Chicago, IL, USA and Missouri, USA?
American Airlines, GoJet Airlines, and United Airlines fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Amtrak operates a train from Chicago Union Station to Kansas City twice daily. Tickets cost $110–250 and the journey takes 7h 23m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $70–490
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $35–250
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $60–390
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 21m
- When
- Every day
- Estimated price
- $70–490
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $35–250
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $40–270
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $60–390
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $100–750
Flights from Chicago Midway International Airport to Kansas City
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $85–600
Flights from Chicago Midway International Airport to Kansas City via Indianapolis
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Chicago Midway International Airport to Kansas City via Milwaukee
- Ave. Duration
- 3h 50m
- When
- Sunday
- Estimated price
- $100–650
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $70–490
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Kansas City via Minneapolis
- Ave. Duration
- 4h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $110–250
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
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