There are 9 ways to get from Chicago to Missouri by subway, plane, train (Amtrak), bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
best- Take the subway from Roosevelt to Midway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)MDW - STL
3h 24m$86–558Train (Amtrak)
cheapest- Take the train from Chicago Union Station to Kansas CitySouthwest Chief / ...
7h 34m$65–180Bus
- Take the bus from Chicago Bus Station to St Louis Bus StationFlixBus N2521 / ...
- Take the bus from St Louis Bus Station to Kansas City Bus StationGreyhound US1200 / ...
11h 40m$73–154Drive 506.6 mi
- Drive from Chicago to Kansas City506.6 mi
8h 33m$93–134Fly Chicago O'Hare International Airport to Columbia Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)ORD - COU
3h 29m$92–350Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)ORD - STL
3h 50m$186–498Fly Chicago O'Hare International Airport to Springfield-Branson National Airport
- Fly from Chicago O'Hare International Airport (ORD) to Springfield-Branson National Airport (SGF)ORD - SGF
3h 42m$68–325Subway to Chicago Midway International Airport, fly to Kansas City
- Take the subway from Roosevelt to Midway
- Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)MDW - MCI
4h 32m$88–555Fly Chicago O'Hare International Airport to Kansas City
- Fly from Chicago O'Hare International Airport (ORD) to Kansas City (MCI)ORD - MCI
5h 2m$142–655
Chicago to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Missouri is to bus which costs $70 - $160 and takes 11h 40m.
The fastest way to get from Chicago to Missouri is to subway and fly which takes 3h 24m and costs $85 - $600.
No, there is no direct bus from Chicago station to Missouri station. However, there are services departing from Chicago Bus Station and arriving at Kansas City Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 11h 40m.
No, there is no direct train from Chicago station to Missouri. However, there are services departing from Chicago Union Station and arriving at Metro Center via Union Station. The journey, including transfers, takes approximately 7h 34m.
The distance between Chicago and Missouri is 278 miles. The road distance is 509.6 miles.
The best way to get from Chicago to Missouri without a car is to train which takes 7h 34m and costs $65 - $180.
It takes approximately 3h 24m to get from Chicago to Missouri, including transfers.
Chicago to Missouri bus services, operated by Flixbus USA, depart from Chicago Bus Station.
Chicago to Missouri train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Chicago to Missouri is to train which takes 7h 34m and costs $65 - $180. Alternatively, you can bus, which costs $70 - $160 and takes 11h 40m, you could also fly, which costs $90 - $350 and takes 3h 29m.
What companies run services between Chicago, IL, USA and Missouri, USA?
Amtrak operates a train from Chicago Union Station to Kansas City twice daily. Tickets cost $65–180 and the journey takes 7h 23m. Alternatively, you can take a bus from Chicago Bus Station to Kansas City Bus Station via St Louis Bus Station in around 11h 40m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 13m
- When
- Every day
- Estimated price
- $80–550
Flights from Chicago Midway International Airport to Kansas City
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $85–550
Flights from Chicago Midway International Airport to Kansas City via Lambert–St. Louis International Airport
- Ave. Duration
- 3h 18m
- When
- Monday, Tuesday, Friday, Saturday, and Sunday
- Estimated price
- $95–550
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 25m
- When
- Every day
- Estimated price
- $60–420
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $50–300
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $65–420
- Website
- united.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 36m
- When
- Every day
- Estimated price
- $40–280
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $60–420
Flights from Chicago O'Hare International Airport to Springfield-Branson National Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $50–300
Flights from Chicago O'Hare International Airport to Kansas City
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $65–420
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $60–420
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $65–180
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to St Louis Bus Station
- Ave. Duration
- 6h 10m
- Frequency
- 5 times a day
- Estimated price
- $35–75
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Chicago to Missouri bus services, operated by Flixbus USA, arrive at St Louis Bus Station.
Chicago to Missouri train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Chicago to Missouri is 510 miles. It takes approximately 8h 33m to drive from Chicago to Missouri.
Book your Chicago to Missouri bus tickets online with Omio and FlixBus.
There are 335+ hotels available in Missouri.