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How to get fromBuffalo to Missouriby plane, train (Amtrak), bus (Greyhound), car, shuttle or bus (Flixbus, Greyhound)

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There are 9 ways to get from Buffalo to Missouri by plane, train (Amtrak), bus (Greyhound), car, shuttle, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Lambert–St. Louis International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL)plane plane BUF - STL
    6h 15m
    $257–1,483

  2. Bus via Toledo

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Indianapolis, INbus bus
    4. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus
    23h
    $117–298

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    20h 25m
    $129–395

  4. Drive 977.1 mi

    1. Drive from Buffalo to Kansas Citycar car 977.1 mi
    16h 39m
    $179–258

  5. Fly Buffalo Niagara International Airport to Columbia Regional Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Columbia Regional Airport (COU)plane plane BUF - COU
    6h 4m
    $184–895

  6. Fly Buffalo Niagara International Airport to Springfield-Branson National Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Springfield-Branson National Airport (SGF)plane plane BUF - SGF
    6h 54m
    $310–1,600

  7. Fly Buffalo Niagara International Airport to Kansas City

    1. Fly from Buffalo Niagara International Airport (BUF) to Kansas City (MCI)plane plane BUF - MCI
    7h 31m
    $214–1,180

  8. Shuttle to Toronto Pearson International Airport, fly to Lambert–St. Louis International Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Lambert–St. Louis International Airport (STL)plane plane YYZ - STL
    7h 57m
    $407–903

  9. Bus

    1. Take the bus from Buffalo to Pittsburghbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus
    27h 19m
    $149–390

Buffalo to Missouri by train and tram (Amtrak)

Calendar14Weekly Services
Duration20h 25mAverage Duration
Ticket$129Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Missouri, USA?

Delta, American Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a train from Buffalo to Metro Center via Buffalo Depew Station, Chicago Union Station, Kansas City, and Union Station in around 20h 25m.

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