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How to get fromBuffalo to Missouriby plane, train (Amtrak), bus (Greyhound), car or shuttle

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There are 8 ways to get from Buffalo to Missouri by plane, train (Amtrak), bus (Greyhound), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Buffalo Niagara International Airport to Lambert–St. Louis International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL)plane plane BUF - STL
    6h 14m
    $235–1,305

  2. Fly Buffalo Niagara International Airport to Springfield-Branson National Airport

    cheapest
    1. Fly from Buffalo Niagara International Airport (BUF) to Springfield-Branson National Airport (SGF)plane plane BUF - SGF
    6h 43m
    $148–772

  3. Train (Amtrak)

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    20h 25m
    $279–684

  4. Bus

    1. Take the bus from Buffalo, NY to Robert K Pfaff Transit Center - Akronbus bus
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Cambridgebus bus
    3. Take the bus from Cambridge, OH to St Louis Bus Stationbus bus
    4. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    23h 50m
    $160–361

  5. Drive 977.1 mi

    1. Drive from Buffalo to Kansas Citycar car 977.1 mi
    16h 39m
    $179–258

  6. Fly Buffalo Niagara International Airport to Columbia Regional Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Columbia Regional Airport (COU)plane plane BUF - COU
    6h 48m
    $172–767

  7. Fly Buffalo Niagara International Airport to Kansas City

    1. Fly from Buffalo Niagara International Airport (BUF) to Kansas City (MCI)plane plane BUF - MCI
    7h 26m
    $192–1,102

  8. Shuttle to Toronto Pearson International Airport, fly to Lambert–St. Louis International Airport

    1. Take a shuttle bus from Buffalo Airport to Pearson International Airport Terminal 1shuttle bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Lambert–St. Louis International Airport (STL)plane plane YYZ - STL
    8h 4m
    $565–2,025

Buffalo to Missouri by train and tram (Amtrak)

Calendar14Weekly Services
Duration20h 25mAverage Duration
Ticket$279Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Missouri, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a train from Buffalo to Metro Center via Buffalo Depew Station, Chicago Union Station, Kansas City, and Union Station in around 20h 25m.

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