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How to get fromBuffalo to Missouriby plane, train (Amtrak), bus (Greyhound), car or bus (Flixbus, Greyhound)

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There are 8 ways to get from Buffalo to Missouri by plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Lambert–St. Louis International Airport

    best
    1. Fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL)plane plane BUF - STL
    5h 50m
    $239–1,431

  2. Bus via Toledo

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus
    2. Take the bus from Cleveland Bus Station to Toledo Bus Stopbus bus
    3. Take the bus from Toledo to Indianapolis, INbus bus
    4. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus
    23h
    $143–317

  3. Train

    1. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Napervilletrain train
    3. Take the train from Naperville Amtrak Station to Kansas Citytrain train
    21h 3m
    $224–581

  4. Drive 977.1 mi

    1. Drive from Buffalo to Kansas Citycar car 977.1 mi
    16h 39m
    $179–258

  5. Fly to Columbia Regional Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Columbia Regional Airport (COU)plane plane BUF - COU
    6h 13m
    $176–793

  6. Fly to Springfield-Branson National Airport

    1. Fly from Buffalo Niagara International Airport (BUF) to Springfield-Branson National Airport (SGF)plane plane BUF - SGF
    6h 22m
    $162–798

  7. Fly to Kansas City

    1. Fly from Buffalo Niagara International Airport (BUF) to Kansas City (MCI)plane plane BUF - MCI
    7h 15m
    $206–1,128

  8. Bus

    1. Take the bus from Buffalo to Pittsburghbus bus
    2. Take the bus from Pittsburgh Intermodal Station to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus bus
    27h 19m
    $164–400

Buffalo to Missouri by train

Calendar13Weekly Trains
Duration21h 3mAverage Duration
Ticket$224Cheapest Price
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Questions & Answers

What companies run services between Buffalo, NY, USA and Missouri, USA?

Delta, Southwest Airlines, and two other airlines fly from Buffalo Niagara International Airport (BUF) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a train from Buffalo to Kansas City via Buffalo Depew Station, Chicago Union Station, and Naperville Amtrak Station in around 21h 3m.

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