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How to get fromChicago to Biloxiby plane, train, bus, bus (Flixbus, Greyhound), car or bus (Greyhound)

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There are 9 ways to get from Chicago to Biloxi by plane, train, bus, bus (Flixbus, Greyhound), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Gulfport-Biloxi Regional Airport (GPT)plane plane ORD - GPT
    6h 21m
    $128–520

  2. Fly Chicago O'Hare International Airport to Louis Armstrong New Orleans International Airport, bus

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Louis Armstrong New Orleans International Airport (MSY)plane plane ORD - MSY
    2. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    8h 25m
    $80–377

  3. Train, bus

    1. Take the train from Chicago Union Station to New Orleans Union Passenger Terminaltrain train City of New Orleans
    2. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus Greyhound US0602
    22h 27m
    $220–502

  4. Bus via Newnan

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Washington St at MLK Jr Dr to Newnan Park and Ridebus bus 453
    3. Take the bus from Newnan Park and Ride to Biloxibus bus
    22h 53m
    $163–319

  5. Drive 900.1 mi

    1. Drive from Chicago to Biloxicar car 900.1 mi
    14h 55m
    $165–238

  6. Fly Chicago Midway International Airport to Gulfport-Biloxi Regional Airport

    1. Fly from Chicago Midway International Airport (MDW) to Gulfport-Biloxi Regional Airport (GPT)plane plane MDW - GPT
    6h 11m
    $178–800

  7. Fly Chicago Midway International Airport to Louis Armstrong New Orleans International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Louis Armstrong New Orleans International Airport (MSY)plane plane MDW - MSY
    2. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    8h 1m
    $104–537

  8. Fly Chicago Midway International Airport to Pensacola International Airport, bus

    1. Fly from Chicago Midway International Airport (MDW) to Pensacola International Airport (PNS)plane plane MDW - PNS
    2. Take the bus from Pensacola Airport to Mobile Bus Stationbus bus
    3. Take the bus from Mobile Bus Station to Biloxi Transit Centerbus bus
    8h 1m
    $118–641

  9. Bus (Greyhound)

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Biloxi Transit Centerbus bus Greyhound US0602
    26h 10m
    $188–344

Chicago to Biloxi by train and bus

Calendar7Weekly Services
Duration22h 27mAverage Duration
Ticket$220Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Biloxi, MS, USA?

Delta, American Airlines, and United Airlines fly from Chicago O'Hare International Airport (ORD) to Gulfport-Biloxi Regional Airport (GPT) every 3 hours. Alternatively, you can take a bus from Chicago Bus Station to Biloxi via Atlanta Bus Station, Washington St at MLK Jr Dr, and Newnan Park and Ride in around 22h 53m.

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