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How to get fromChicago to Gainesvilleby plane, bus (Flixbus, Greyhound), train, bus, car or bus (Greyhound)

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There are 9 ways to get from Chicago to Gainesville by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Gainesville Regional Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Gainesville Regional Airport (GNV)planeORD - GNV
    7h 52m
    $74–387
  2. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus StationbusFlixBus 2512 / ...
    2. Take the bus from Atlanta Bus Station to GainesvillebusFlixBus 2415 / ...
    21h 20m
    $118–288
  3. Train, bus

    1. Take the train from Chicago Union Station to JacksonvilletrainFloridian
    2. Take the bus from Jacksonville to GainesvillebusFlixBus 2431
    38h 9m
    $206–674
  4. Drive 998 mi

    1. Drive from Chicago to Gainesvillecar998 mi
    17h 49m
    $183–264
  5. Fly Chicago Midway International Airport to Gainesville Regional Airport

    1. Fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV)planeMDW - GNV
    7h 3m
    $94–477
  6. Fly Chicago Midway International Airport to Jacksonville, bus

    1. Fly from Chicago Midway International Airport (MDW) to Jacksonville (JAX)planeMDW - JAX
    2. Take the bus from Jacksonville to Gainesvillebus
    7h 49m
    $140–682
  7. Fly Chicago O'Hare International Airport to Jacksonville, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Jacksonville (JAX)planeORD - JAX
    2. Take the bus from Jacksonville to Gainesvillebus
    8h 15m
    $116–532
  8. Fly Chicago Midway International Airport to Orlando, bus

    1. Fly from Chicago Midway International Airport (MDW) to Orlando (MCO)planeMDW - MCO
    2. Take the bus from Orlando RedCoach Station to Gainesvillebus
    7h 21m
    $94–487
  9. Bus via North Walmart Supercenter (Greyhound)

    1. Take the bus from Chicago Train Station to Atlanta Bus StationbusGreyhound US0100
    2. Take the bus from Atlanta Bus Station to Gainesville Bus StopbusGreyhound US0630
    23h 53m
    $125–283

Chicago to Gainesville by bus

Calendar29Weekly Buses
Duration21h 20mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Gainesville, FL, USA?

American Airlines and Delta fly from Chicago O'Hare International Airport (ORD) to Gainesville Regional Airport (GNV) hourly. Alternatively, you can take a bus from Chicago Bus Station to Gainesville via Atlanta Bus Station in around 21h 20m.

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