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How to get fromChicago to Gainesvilleby plane, bus (Flixbus, Greyhound), train, bus, car or bus (Greyhound)

Find Transport to Gainesville

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There are 9 ways to get from Chicago to Gainesville by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Gainesville Regional Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV)plane plane MDW - GNV
    7h 3m
    $144–757
  2. Fly Chicago Midway International Airport to Orlando, bus

    cheapest
    1. Fly from Chicago Midway International Airport (MDW) to Orlando (MCO)plane plane MDW - MCO
    2. Take the bus from Orlando RedCoach Station to Gainesvillebus bus
    7h 26m
    $108–507
  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus FlixBus 2512 / ...
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus FlixBus 2415 / ...
    21h 20m
    $118–288
  4. Train, bus

    1. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Gainesvillebus bus FlixBus 2431
    38h 9m
    $206–674
  5. Drive 998 mi

    1. Drive from Chicago to Gainesvillecar car 998 mi
    17h 49m
    $183–264
  6. Fly Chicago O'Hare International Airport to Gainesville Regional Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Gainesville Regional Airport (GNV)plane plane ORD - GNV
    7h 52m
    $114–607
  7. Fly Chicago Midway International Airport to Jacksonville, bus

    1. Fly from Chicago Midway International Airport (MDW) to Jacksonville (JAX)plane plane MDW - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    7h 49m
    $140–682
  8. Fly Chicago O'Hare International Airport to Jacksonville, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Jacksonville (JAX)plane plane ORD - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    8h 19m
    $116–522
  9. Bus via North Walmart Supercenter (Greyhound)

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus Greyhound US0630
    23h 53m
    $125–283

Chicago to Gainesville by bus

Calendar29Weekly Buses
Duration21h 20mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Gainesville, FL, USA?

Delta, Frontier Airlines, and two other airlines fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV) 4 times a day. Alternatively, you can take a bus from Chicago Bus Station to Gainesville via Atlanta Bus Station in around 21h 20m.

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