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How to get fromChicago to Gainesvilleby plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

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There are 10 ways to get from Chicago to Gainesville by plane, bus (Greyhound, Flixbus), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Gainesville Regional Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Gainesville Regional Airport (GNV)plane plane ORD - GNV
    7h 26m
    $90–427

  2. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus FlixBus 2512 / ...
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus FlixBus N2401 / ...
    20h 35m
    $165–306

  3. Train, bus

    1. Take the train from Chicago Union Station to Jacksonvilletrain train Floridian
    2. Take the bus from Jacksonville to Gainesvillebus bus FlixBus 2431
    38h 16m
    $519–1,036

  4. Drive 998 mi

    1. Drive from Chicago to Gainesvillecar car 998 mi
    18h
    $183–264

  5. Fly Chicago Midway International Airport to Gainesville Regional Airport

    1. Fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV)plane plane MDW - GNV
    6h 55m
    $114–557

  6. Fly Chicago Midway International Airport to Jacksonville, bus

    1. Fly from Chicago Midway International Airport (MDW) to Jacksonville (JAX)plane plane MDW - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    7h 52m
    $124–626

  7. Fly Chicago O'Hare International Airport to Jacksonville, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Jacksonville (JAX)plane plane ORD - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    8h 16m
    $194–526

  8. Fly Chicago Midway International Airport to Orlando, bus

    1. Fly from Chicago Midway International Airport (MDW) to Orlando (MCO)plane plane MDW - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    7h 46m
    $234–552

  9. Fly Chicago Midway International Airport to Tampa, bus

    1. Fly from Chicago Midway International Airport (MDW) to Tampa (TPA)plane plane MDW - TPA
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    8h 48m
    $146–642

  10. Bus via North Walmart Supercenter

    1. Take the bus from Chicago Train Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus bus Greyhound US0630
    24h 3m
    $166–317

Chicago to Gainesville by bus

Calendar67Weekly Buses
Duration20h 35mAverage Duration
Ticket$165Cheapest Price
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Questions & Answers

Map of how to get from Chicago to Gainesville.ExpandLaunch map view
  • Distance: 930.4 mi
  • Duration: 7h 26m

What companies run services between Chicago, IL, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Chicago O'Hare International Airport (ORD) to Gainesville Regional Airport (GNV) every 3 hours. Alternatively, you can take a bus from Chicago Bus Station to Gainesville via Atlanta Bus Station in around 20h 35m.

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