There are 9 ways to get from Chicago to Gainesville by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago Midway International Airport to Gainesville Regional Airport
best- Fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV)plane MDW - GNV
7h 8m$100–557Fly Chicago O'Hare International Airport to Gainesville Regional Airport
cheapest- Fly from Chicago O'Hare International Airport (ORD) to Gainesville Regional Airport (GNV)plane ORD - GNV
7h 50m$70–377Bus
- Take the bus from Chicago Bus Station to Atlanta Bus Stationbus FlixBus 2512 / ...
- Take the bus from Atlanta Bus Station to Gainesvillebus FlixBus N2401 / ...
21h$118–215Train, bus
- Take the train from Chicago Union Station to Jacksonvilletrain Floridian
- Take the bus from Jacksonville to Gainesvillebus FlixBus 2431
38h 9m$207–420Drive 998.1 mi
- Drive from Chicago to Gainesvillecar 998.1 mi
17h 59m$183–264Fly Chicago Midway International Airport to Jacksonville, bus
- Fly from Chicago Midway International Airport (MDW) to Jacksonville (JAX)plane MDW - JAX
- Take the bus from Jacksonville to Gainesvillebus
7h 49m$140–730Fly Chicago O'Hare International Airport to Jacksonville, bus
- Fly from Chicago O'Hare International Airport (ORD) to Jacksonville (JAX)plane ORD - JAX
- Take the bus from Jacksonville to Gainesvillebus
8h 15m$110–520Fly Chicago Midway International Airport to Orlando, bus
- Fly from Chicago Midway International Airport (MDW) to Orlando (MCO)plane MDW - MCO
- Take the bus from Orlando RedCoach Station to Gainesvillebus
7h 25m$116–617Bus via North Walmart Supercenter (Greyhound)
- Take the bus from Chicago Train Station to Atlanta Bus Stationbus Greyhound US0100
- Take the bus from Atlanta Bus Station to Gainesville Bus Stopbus Greyhound US0630
25h 13m$120–223
Chicago to Gainesville by bus
Questions & Answers
The cheapest way to get from Chicago to Gainesville is to bus which costs $110 - $220 and takes 21h.
The fastest way to get from Chicago to Gainesville is to fly which takes 7h 8m and costs $95 - $600.
No, there is no direct bus from Chicago station to Gainesville. However, there are services departing from Chicago Bus Station and arriving at Gainesville via Atlanta Bus Station. The journey, including transfers, takes approximately 21h.
The distance between Chicago and Gainesville is 913 miles. The road distance is 1003.9 miles.
The best way to get from Chicago to Gainesville without a car is to bus which takes 21h and costs $110 - $220.
It takes approximately 7h 8m to get from Chicago to Gainesville, including transfers.
Chicago to Gainesville bus services, operated by Flixbus USA, depart from Chicago Bus Station.
The best way to get from Chicago to Gainesville is to fly which takes 7h 8m and costs $95 - $600. Alternatively, you can bus, which costs $110 - $220 and takes 21h.
Chicago to Gainesville bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Gainesville is 1h ahead of Chicago. It is currently 12:15 AM in Chicago and 1:15 AM in Gainesville.
What companies run services between Chicago, IL, USA and Gainesville, FL, USA?
Delta, Southwest Airlines, and two other airlines fly from Chicago Midway International Airport (MDW) to Gainesville Regional Airport (GNV) 5 times a day. Alternatively, you can take a bus from Chicago Bus Station to Gainesville via Atlanta Bus Station in around 21h.
- Website
- aa.com
Flights from Chicago Midway International Airport to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 4h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Chicago O'Hare International Airport to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $70–380
Flights from Chicago O'Hare International Airport to Gainesville Regional Airport via Miami
- Ave. Duration
- 5h 25m
- When
- Thursday and Saturday
- Estimated price
- $95–460
Flights from Chicago O'Hare International Airport to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 24m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
Flights from Chicago O'Hare International Airport to Jacksonville
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $90–490
- Website
- southwest.com
Flights from Chicago Midway International Airport to Jacksonville
- Ave. Duration
- 2h 15m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–700
Flights from Chicago Midway International Airport to Jacksonville via Nashville
- Ave. Duration
- 3h 57m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $130–700
Flights from Chicago Midway International Airport to Jacksonville via St. Louis
- Ave. Duration
- 4h 20m
- When
- Saturday
- Estimated price
- $140–750
Flights from Chicago O'Hare International Airport to Jacksonville via Nashville
- Ave. Duration
- 4h 45m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $90–490
Flights from Chicago Midway International Airport to Orlando
- Ave. Duration
- 2h 39m
- When
- Every day
- Estimated price
- $90–470
Flights from Chicago Midway International Airport to Orlando via Nashville
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–480
- Website
- delta.com
Flights from Chicago Midway International Airport to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 4h 51m
- When
- Every day
- Estimated price
- $95–550
Flights from Chicago O'Hare International Airport to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 5h 38m
- When
- Every day
- Estimated price
- $65–370
Flights from Chicago Midway International Airport to Jacksonville via Atlanta
- Ave. Duration
- 4h 34m
- When
- Every day
- Estimated price
- $130–700
Flights from Chicago O'Hare International Airport to Jacksonville via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $90–490
- Website
- united.com
Flights from Chicago O'Hare International Airport to Jacksonville
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- $90–490
- Website
- flyfrontier.com
Flights from Chicago Midway International Airport to Orlando
- Ave. Duration
- 2h 49m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–470
- Website
- allegiantair.com
Flights from Chicago Midway International Airport to Jacksonville via Knoxville
- Ave. Duration
- 5h 10m
- When
- Thursday
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Jacksonville
- Ave. Duration
- 34h 45m
- Frequency
- Once daily
- Estimated price
- $190–400
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 14h 25m
- Frequency
- 3 times a day
- Estimated price
- $75–150
- Schedules at
- flixbus.com
Bus from Atlanta Bus Station to Gainesville
- Ave. Duration
- 5h 35m
- Frequency
- 4 times a day
- Estimated price
- $40–65
- Schedules at
- flixbus.com
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $16–22
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Atlanta Bus Station
- Ave. Duration
- 16h 25m
- Frequency
- 4 times a day
- Estimated price
- $75–140
- Website
- https://www.greyhound.com/
Bus from Chicago Train Station to Atlanta Bus Station
- Ave. Duration
- 16h 5m
- Frequency
- Twice daily
- Estimated price
- $75–150
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Gainesville Bus Stop
- Ave. Duration
- 6h 45m
- Frequency
- Once daily
- Estimated price
- $40–75
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Orlando RedCoach Station to Gainesville
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
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More Questions & Answers
Yes, the driving distance between Chicago to Gainesville is 1004 miles. It takes approximately 17h 59m to drive from Chicago to Gainesville.
Book your Chicago to Gainesville bus tickets online with Omio and FlixBus.
There are 249+ hotels available in Gainesville.










