There are 6 ways to get from Chicago to Louisville by subway, plane, bus (Amtrak), train, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly to Louisville International Airport
best- Take the subway from Roosevelt to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane MDW - SDF
3h 53m$88–608Bus (Amtrak)
cheapest- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
7h$50–60Train, bus (Amtrak)
- Take the train from Chicago Union Station to Indianapolistrain Cardinal
- Take the bus from Indianapolis Union Station to Louisville, KYbus Chicago
8h 19m$66–144Drive 293.6 mi
- Drive from Chicago to Louisvillecar 293.6 mi
5h 4m$54–78Fly Chicago O'Hare International Airport to Louisville International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
4h 23m$244–458Fly Chicago O'Hare International Airport to Blue Grass Airport, drive
- Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane ORD - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
4h 30m$100–624
Chicago to Louisville by bus (Amtrak)
Questions & Answers
The cheapest way to get from Chicago to Louisville is to bus which costs $50 - $60 and takes 7h.
The fastest way to get from Chicago to Louisville is to subway and fly which takes 3h 53m and costs $85 - $650.
Yes, there is a direct bus departing from Chicago Union Station station and arriving at Louisville, KY. Services depart twice daily, and operate every day. The journey takes approximately 7h.
The distance between Chicago and Louisville is 288 miles. The road distance is 295.3 miles.
The best way to get from Chicago to Louisville without a car is to bus which takes 7h and costs $50 - $60.
It takes approximately 3h 53m to get from Chicago to Louisville, including transfers.
Chicago to Louisville bus services, operated by Amtrak Thruway, depart from Chicago Union Station.
The best way to get from Chicago to Louisville is to bus which takes 7h and costs $50 - $60. Alternatively, you can fly, which costs $240 - $460 and takes 4h 23m.
Chicago to Louisville bus services, operated by Amtrak Thruway, arrive at Louisville, KY station.
Louisville is 1h ahead of Chicago. It is currently 5:40 AM in Chicago and 6:40 AM in Louisville.
What companies run services between Chicago, IL, USA and Louisville, KY, USA?
Amtrak Thruway operates a bus from Chicago Union Station to Louisville, KY twice daily. Tickets cost $50–60 and the journey takes 7h. Alternatively, American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF) every 3 hours.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $55–380
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 24m
- When
- Every day
- Estimated price
- $85–600
- Website
- united.com
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $55–380
Flights from Chicago O'Hare International Airport to Blue Grass Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $85–600
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 14m
- When
- Every day
- Estimated price
- $85–600
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Roosevelt to Midway
- Ave. Duration
- 20 min
- Frequency
- Every 10 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $40–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 7h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- https://www.amtrak.com/home.html
- Adult
- $50–60
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Chicago to Louisville is 295 miles. It takes approximately 5h 4m to drive from Chicago to Louisville.
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