Travel options for:
Chicago to Louisville
  • Bus Greyhound USA

    $29 - $85
    1. Chicago, IL

      5 h 43 min - once daily

      $29 - $85

  • Train, bus

    $59 - $143
    1. Chicago Union Station Amtrak

      4 h 54 min - 4 times a week

      $40 - $100

    2. Indianapolis, IN

      2 h 15 min - once daily

      $18 - $45

  • Train, bus via Indianapolis, IN

    $53 - $121
    1. Chicago Union Station Amtrak

      4 h 54 min - 4 times a week

      $40 - $100

    2. Indianapolis Amtrak

      14 min - 3985 feet

    3. Indianapolis, IN

      2 h 24 min - twice daily

      $12 - $23

  • Bus Hoosier Ride

    $67 - $104
    1. Chicago, IL

      45 min - once daily - line 0358

      $17 - $25

    2. Hammond, IN

      8 h 15 min - once daily

      $50 - $80

  • Drive

    $29 - $45
    1. Chicago

      4 h 52 min - 296.7 miles

      $29 - $45

  • Fly Chicago Midway to Louisville

    $153 - $247
    1. Chicago

      23 min - every 15 minutes

      $2 - $4

    2. Chicago Midway (MDW)

      1 h 5 min - non-stop

      $150 - $240

    3. Louisville (SDF)

      28 min - hourly - line 02

      $1 - $3

  • Fly Chicago O'Hare to Louisville

    $103 - $238
    1. Chicago

      43 min - every 10 minutes

      $2 - $5

    2. Chicago O'Hare (ORD)

      1 h 11 min - non-stop

      $100 - $230

    3. Louisville (SDF)

      28 min - hourly - line 02

      $1 - $3

  • Fly Chicago O'Hare to Lexington, bus

    $224 - $675
    1. Chicago

      43 min - every 10 minutes

      $2 - $5

    2. Chicago O'Hare (ORD)

      1 h 17 min - non-stop

      $170 - $600

    3. Lexington (LEX)

      11 min - 8.2 miles

      $28 - $35

    4. Lexington, KY

      1 h 40 min - once daily

      $24 - $35

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From Chicago, IL bus to Louisville, KY. 5 h 43 min $51. From Chicago Union Station Amtrak train to Indianapolis, IN then bus to Louisville, KY. 8 h 9 min $100. From Chicago Union Station Amtrak train to Indianapolis Amtrak, walk to Indianapolis, IN, then bus to Louisville, KY. 8 h 32 min $89. From Chicago, IL line 0358 bus to Hammond, IN then bus to Louisville, KY. 10 h $76. From Chicago drive to Louisville. 4 h 52 min $35. From Adams/Wabash subway to Chicago Midway airport, fly to Louisville airport, then line 02 bus to Louisville. 3 h 33 min $236. From Jackson-Blue subway to Chicago O'Hare airport, fly to Louisville airport, then line 02 bus to Louisville. 3 h 59 min $217. From Jackson-Blue subway to Chicago O'Hare airport, fly to Lexington airport, taxi to Lexington, KY, then bus to Louisville. 5 h 51 min $369.