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How to get fromCharlottesville to St. Louisby plane, bus (Greyhound, Flixbus), train, bus, car, taxi, or train (Amtrak)

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There are 7 ways to get from Charlottesville to St. Louis by plane, bus (Greyhound, Flixbus), train, bus, car, taxi, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charlottesville

    best
    1. Fly from Charlottesville (CHO) to Lambert–St. Louis International Airport (STL)plane plane CHO - STL
    5h 26m
    $176–792

  2. Bus

    cheapest
    1. Take the bus from Charlottesville Union Station to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus Greyhound US0186 / ...
    20h
    $121–251

  3. Train, bus

    1. Take the train from Charlottesville to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    20h 18m
    $218–446

  4. Drive 743 mi

    1. Drive from Charlottesville to St. Louiscar car 743 mi
    12h 35m
    $136–196

  5. Taxi to Shenandoah Valley Regional Airport, fly

    1. Take the taxi from Charlottesville to Shenandoah Valley Regional Airport (SHD)taxi taxi
    2. Fly from Shenandoah Valley Regional Airport (SHD) to Lambert–St. Louis International Airport (STL)plane plane SHD - STL
    6h 6m
    $298–925

  6. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Charlottesville to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    6h 12m
    $275–1,370

  7. Train (Amtrak)

    1. Take the train from Charlottesville to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    26h 39m
    $328–677

Charlottesville to St. Louis by bus

Calendar7Weekly Buses
Duration20hAverage Duration
Ticket$121Cheapest Price
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Questions & Answers

Map of how to get from Charlottesville to St. Louis.ExpandLaunch map view
  • Distance: 669.1 mi
  • Duration: 5h 26m

What companies run services between Charlottesville, VA, USA and St. Louis, MO, USA?

United Airlines, American Airlines, and Delta fly from Charlottesville (CHO) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, you can take a bus from Downtown Transit Station to St Louis Bus Station via W Main St at 8th St NW, Charlottesville Union Station, and Nashville Bus Station in around 20h.

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