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How to get fromCharlottesville to St. Louisby plane, bus (Greyhound, Flixbus), train, bus, car or train (Amtrak)

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There are 6 ways to get from Charlottesville to St. Louis by plane, bus (Greyhound, Flixbus), train, bus, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Charlottesville

    best
    1. Fly from Charlottesville (CHO) to Lambert–St. Louis International Airport (STL)plane plane CHO - STL
    5h 27m
    $176–792

  2. Train, bus

    cheapest
    1. Take the train from Charlottesville to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421 / ...
    20h 18m
    $91–133

  3. Bus

    1. Take the bus from Charlottesville Union Station to Nashville Bus Stationbus bus Greyhound US0600
    2. Take the bus from Nashville Bus Station to St Louis Bus Stationbus bus FlixBus N2521
    19h 25m
    $96–267

  4. Drive 743.9 mi

    1. Drive from Charlottesville to St. Louiscar car 743.9 mi
    12h 33m
    $136–197

  5. Train to Ronald Reagan Washington National Airport, fly

    1. Take the train from Charlottesville to Alexandriatrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Lambert–St. Louis International Airport (STL)plane plane DCA - STL
    6h 31m
    $268–1,638

  6. Train (Amtrak)

    1. Take the train from Charlottesville to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    26h 54m
    $150–357

Charlottesville to St. Louis by bus

Calendar7Weekly Buses
Duration19h 25mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

What companies run services between Charlottesville, VA, USA and St. Louis, MO, USA?

United Airlines, Delta, and American Airlines fly from Charlottesville (CHO) to Lambert–St. Louis International Airport (STL) every 3 hours. Alternatively, you can take a bus from Downtown Transit Station to St Louis Bus Station via W Main St at 8th St NW, Charlottesville Union Station, and Nashville Bus Station in around 19h 25m.

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