There are 6 ways to get from Appleton to West Lafayette by bus (Flixbus, Greyhound), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Chicago
best- Take the bus from Appleton Transit Center to Chicago Bus Stationbus FlixBus 2550
- Take the bus from Chicago Train Station to Lafayette Bus Stopbus Greyhound US0100
7h 57m$47–84Bus
cheapest- Take the bus from Appleton Transit Center to Chicago Bus Stationbus FlixBus 2550
- Take the bus from Chicago Bus Station to Lafayette Bus Stopbus FlixBus 2511 / ...
8h 10m$42–89Bus, train
- Take the bus from Appleton Amtrak Station to Milwaukeebus
- Take the train from Milwaukee to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Lafayette Amtrak Stationtrain
8h 53m$73–191Drive 309.2 mi
- Drive from Appleton to West Lafayettecar 309.2 mi
5h 35m$57–82Fly from Appleton International Airport
- Fly from Appleton International Airport (ATW) to Purdue University Airport (LAF)plane ATW - LAF
4h 58m$59–313Fly from Green Bay
- Fly from Green Bay (GRB) to Purdue University Airport (LAF)plane GRB - LAF
5h 45m$77–333
Appleton to West Lafayette by bus and foot
Questions & Answers
The cheapest way to get from Appleton to West Lafayette is to bus via Chicago which costs $45 - $85 and takes 7h 57m.
The fastest way to get from Appleton to West Lafayette is to fly which takes 4h 58m and costs $55 - $320.
No, there is no direct bus from Appleton to West Lafayette. However, there are services departing from Appleton Transit Center and arriving at Lafayette Bus Stop via Chicago Train Station. The journey, including transfers, takes approximately 7h 57m.
The distance between Appleton and West Lafayette is 316 miles. The road distance is 311 miles.
The best way to get from Appleton to West Lafayette without a car is to bus via Chicago which takes 7h 57m and costs $45 - $85.
It takes approximately 7h 57m to get from Appleton to West Lafayette, including transfers.
Appleton to West Lafayette bus services, operated by Flixbus USA, depart from Appleton Transit Center station.
The best way to get from Appleton to West Lafayette is to bus via Chicago which takes 7h 57m and costs $45 - $85. Alternatively, you can fly, which costs $55 - $320 and takes 4h 58m.
Appleton to West Lafayette bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
West Lafayette is 1h ahead of Appleton. It is currently 5:26 AM in Appleton and 6:26 AM in West Lafayette.
What companies run services between Appleton, WI, USA and West Lafayette, IN, USA?
You can take a bus from Appleton Transit Center to Lafayette Bus Stop via Chicago Bus Station and Chicago Train Station in around 7h 57m. Alternatively, United Airlines and American Airlines fly from Appleton International Airport (ATW) to Purdue University Airport (LAF) 3 times a day.
- Website
- united.com
Flights from Appleton International Airport to Purdue University Airport via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $40–290
Flights from Green Bay to Purdue University Airport via Chicago O'Hare
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $40–290
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Milwaukee to Chicago Union Station
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $24–55
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Lafayette Amtrak Station
- Ave. Duration
- 3h 1m
- Frequency
- 3 times a week
- Estimated price
- $35–80
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Appleton Transit Center to Chicago Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $25–45
- Schedules at
- flixbus.com
Bus from Appleton Amtrak Station to Milwaukee
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $13–24
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Lafayette Bus Stop
- Ave. Duration
- 2h 40m
- Frequency
- Every 4 hours
- Estimated price
- $16–28
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Train Station to Lafayette Bus Stop
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Lafayette Bus Stop
- Ave. Duration
- 3h 15m
- Frequency
- 3 times a day
- Estimated price
- $22–45
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Appleton Amtrak Station to Milwaukee
- Ave. Duration
- 2h 23m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- https://www.amtrak.com/home.html
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Appleton Amtrak Station to Milwaukee
- Ave. Duration
- 2h 35m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
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More Questions & Answers
Yes, the driving distance between Appleton to West Lafayette is 311 miles. It takes approximately 5h 35m to drive from Appleton to West Lafayette.
Book your Appleton to West Lafayette bus tickets online with Omio and FlixBus.
There are 106+ hotels available in West Lafayette.









