What is the cheapest way to get from Appleton to Des Moines?

The cheapest way to get from Appleton to Des Moines is to drive which costs $65 - $100 and takes 7h 5m.

What is the fastest way to get from Appleton to Des Moines?

The fastest way to get from Appleton to Des Moines is to fly which takes 4h 12m and costs $130 - $700.

Is there a direct bus between Appleton and Des Moines?

No, there is no direct bus from Appleton to Des Moines. However, there are services departing from Appleton Transit Center and arriving at Des Moines via Chicago Bus Station. The journey, including transfers, takes approximately 12h.

How far is it from Appleton to Des Moines?

The distance between Appleton and Des Moines is 334 miles. The road distance is 380.8 miles.

How do I travel from Appleton to Des Moines without a car?

The best way to get from Appleton to Des Moines without a car is to bus which takes 12h and costs $80 - $160.

How long does it take to get from Appleton to Des Moines?

It takes approximately 4h 12m to get from Appleton to Des Moines, including transfers.

Where do I catch the Appleton to Des Moines bus from?

Appleton to Des Moines bus services, operated by Flixbus USA, depart from Appleton Transit Center station.

Bus or fly from Appleton to Des Moines?

The best way to get from Appleton to Des Moines is to fly which takes 4h 12m and costs $130 - $700. Alternatively, you can bus, which costs $80 - $160 and takes 12h.

Where does the Appleton to Des Moines bus arrive?

Appleton to Des Moines bus services, operated by Flixbus USA, arrive at Chicago Bus Station.

Can I drive from Appleton to Des Moines?

Yes, the driving distance between Appleton to Des Moines is 381 miles. It takes approximately 7h 5m to drive from Appleton to Des Moines.

How do I get a bus ticket from Appleton to Des Moines?

Book your Appleton to Des Moines bus tickets online with Omio and FlixBus.

Where can I stay near Des Moines?

There are 257+ hotels available in Des Moines.

Appleton to Des Moines - 6 ways to travel via train, plane, bus, and car

There are 6 ways to get from Appleton to Des Moines by plane, bus (Flixbus, Greyhound), car, bus, train, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly from Appleton International Airport
best
1. Fly from Appleton International Airport (ATW) to Des Moines (DSM)plane ATW - DSM
4h 12m
$135–693
Drive 378.6 mi
cheapest
1. Drive from Appleton to Des Moinescar 378.6 mi
7h 5m
$70–100
Bus
1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus FlixBus 2550
2. Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
12h
$81–153
Fly from Green Bay
1. Fly from Green Bay (GRB) to Des Moines (DSM)plane GRB - DSM
5h 41m
$153–713
Bus, train
1. Take the bus from Appleton to Milwaukeebus
2. Take the train from Milwaukee to Chicago Union Stationtrain
3. Take the bus from Chicago Bus Station to Des Moinesbus
12h 43m
$93–188
Bus, shuttle
1. Take the bus from Appleton Valley Transit to La Crosse Grand River Stationbus
2. Take the bus from La Crosse to Rochester, MNbus
3. Take a shuttle bus from Rochester Sinclair to Owatonna, MNshuttle
4. Take the bus from Owatonna to Des Moinesbus
13h 35m
$118–189

Appleton to Des Moines by bus

5Weekly Buses

12hAverage Duration

$81Cheapest Price

See schedules

Questions & Answers

Map of how to get from Appleton to Des Moines.

Launch map view

Distance: 332.4 mi
Duration: 4h 12m

What companies run services between Appleton, WI, USA and Des Moines, IA, USA?

Delta, United Airlines, and American Airlines fly from Appleton International Airport (ATW) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Appleton Transit Center to Des Moines via Chicago Bus Station in around 12h.

Airlines

Train operators

Bus operators

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