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How to get fromAppleton to Des Moinesby plane, bus (Flixbus, Greyhound), car, bus, shuttle, or train

Find Transport to Des Moines

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There are 6 ways to get from Appleton to Des Moines by plane, bus (Flixbus, Greyhound), car, bus, shuttle, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Appleton International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Des Moines (DSM)plane plane ATW - DSM
    4h 8m
    $135–693
  2. Drive 378.6 mi

    cheapest
    1. Drive from Appleton to Des Moinescar car 378.6 mi
    7h 5m
    $70–100
  3. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    12h
    $75–141
  4. Fly from Green Bay

    1. Fly from Green Bay (GRB) to Des Moines (DSM)plane plane GRB - DSM
    5h 37m
    $193–913
  5. Bus, shuttle

    1. Take the bus from Appleton Valley Transit to UW-La Crossebus bus
    2. Take the bus from University of Wisconsin - La Crosse to Rochester, MNbus bus
    3. Take a shuttle bus from Rochester Sinclair to Owatonna, MNshuttle bus
    4. Take the bus from Owatonna to Des Moinesbus bus
    14h 10m
    $118–189
  6. Bus, train

    1. Take the bus from Appleton to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    4. Take the bus from Galesburg to Des Moinesbus bus
    14h 40m
    $113–237

Appleton to Des Moines by bus

Calendar5Weekly Buses
Duration12hAverage Duration
Ticket$75Cheapest Price
See schedules

Questions & Answers

What companies run services between Appleton, WI, USA and Des Moines, IA, USA?

United Airlines, Delta, and two other airlines fly from Appleton International Airport (ATW) to Des Moines (DSM) hourly. Alternatively, you can take a bus from Appleton Transit Center to Des Moines via Chicago Bus Station in around 12h.

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