Rome2Rio

How to get fromAppleton to Des Moinesby plane, bus (Flixbus, Greyhound), car, bus, train or bus (Amtrak)

Find Transport to Des Moines

See all options

There are 6 ways to get from Appleton to Des Moines by plane, bus (Flixbus, Greyhound), car, bus, train, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Appleton International Airport

    best
    1. Fly from Appleton International Airport (ATW) to Des Moines (DSM)plane plane ATW - DSM
    3h 49m
    $85–373
  2. Drive 378.6 mi

    cheapest
    1. Drive from Appleton to Des Moinescar car 378.6 mi
    7h 5m
    $70–100
  3. Bus

    1. Take the bus from Appleton Transit Center to Chicago Bus Stationbus bus FlixBus 2550
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123 / ...
    12h 4m
    $71–122
  4. Fly from Green Bay

    1. Fly from Green Bay (GRB) to Des Moines (DSM)plane plane GRB - DSM
    5h 39m
    $108–393
  5. Bus, train

    1. Take the bus from Appleton Amtrak Station to Milwaukeebus bus
    2. Take the train from Milwaukee to Chicago Union Stationtrain train
    3. Take the bus from Chicago Bus Station to Des Moinesbus bus
    12h 35m
    $76–203
  6. Bus via Saint Paul

    1. Take the bus from Appleton to Wausau Transit Centerbus bus
    2. Take the bus from Wausau Amtrak Bus Stop to St. Paul-Minneapolisbus bus
    3. Take the bus from MSP Airport to Des Moinesbus bus
    14h 45m

Appleton to Des Moines by bus

Calendar5Weekly Buses
Duration12h 4mAverage Duration
Ticket$71Cheapest Price
See schedules

Questions & Answers

What companies run services between Appleton, WI, USA and Des Moines, IA, USA?

Delta, American Airlines, and United Airlines fly from Appleton International Airport (ATW) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from Appleton Transit Center to Des Moines via Chicago Bus Station in around 12h 4m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers